Objectives:To determine COVID-19 mortality and its risk factors in hospitalized patients at of a tertiary care center in north India.Methods:A retrospective observational study was conducted of patients who were hospi...Objectives:To determine COVID-19 mortality and its risk factors in hospitalized patients at of a tertiary care center in north India.Methods:A retrospective observational study was conducted of patients who were hospitalized from May 2020 to January 2021.The in-hospital mortality was assessed,and demographic variables and comorbidities between COVID-19 deaths and survivors were compared.Results:A total of 24000 patients were admitted during the study period,among which 17000 had shown positive results of the RT-PCR test for COVID-19.The total mortality was 329 patients(1.37%),among which 232(70.52%)succumbed due to COVID-19,and 97(29.48%)died due to other illnesses.The mean age of the patients was(64.09依16.99)years.The mean age was significantly higher in COVID-19 related deaths[(67.63±13.78)years]as compared to that of the survivors[(60.52±19.5)years](P<0.001).Compared to COVID-19 survivors,there were more males(72.41%v.s.61.5%)and less females(27.59%v.s.38.5%)in COVID-19 related deaths(P=0.001).Comorbidities such as hypertension,diabetes mellitus,and chronic kidney disease showed a significant correlation with COVID-19 mortality with an adjusted odds ratio of 2.389(95%CI:1.465-2.982),3.891(95%CI:2.059-5.392),and 6.358(95%CI:5.675-10.564),respectively.Conclusions:Elderly males with comorbidities have higher risk for mortality related to COVID-19.Ongoing vaccination drive is rightfully prioritised to serve the high-risk category first.展开更多
文摘Objectives:To determine COVID-19 mortality and its risk factors in hospitalized patients at of a tertiary care center in north India.Methods:A retrospective observational study was conducted of patients who were hospitalized from May 2020 to January 2021.The in-hospital mortality was assessed,and demographic variables and comorbidities between COVID-19 deaths and survivors were compared.Results:A total of 24000 patients were admitted during the study period,among which 17000 had shown positive results of the RT-PCR test for COVID-19.The total mortality was 329 patients(1.37%),among which 232(70.52%)succumbed due to COVID-19,and 97(29.48%)died due to other illnesses.The mean age of the patients was(64.09依16.99)years.The mean age was significantly higher in COVID-19 related deaths[(67.63±13.78)years]as compared to that of the survivors[(60.52±19.5)years](P<0.001).Compared to COVID-19 survivors,there were more males(72.41%v.s.61.5%)and less females(27.59%v.s.38.5%)in COVID-19 related deaths(P=0.001).Comorbidities such as hypertension,diabetes mellitus,and chronic kidney disease showed a significant correlation with COVID-19 mortality with an adjusted odds ratio of 2.389(95%CI:1.465-2.982),3.891(95%CI:2.059-5.392),and 6.358(95%CI:5.675-10.564),respectively.Conclusions:Elderly males with comorbidities have higher risk for mortality related to COVID-19.Ongoing vaccination drive is rightfully prioritised to serve the high-risk category first.
