Cytomegalovirus(CMV)has been increasingly recognized as an important common pathogen in an immunocompromised state.The colon and stomach are the most common sites of its gastrointestinal infection. Symptoms of CMV gas...Cytomegalovirus(CMV)has been increasingly recognized as an important common pathogen in an immunocompromised state.The colon and stomach are the most common sites of its gastrointestinal infection. Symptoms of CMV gastritis are usually nonspecific and include epigastric pain,fever,nausea and bleeding. Endoscopic features are quite variable and include macroscopically normal mucosa,diffuse erythema, nodules,pseudotumors,erosions and ulcers.The bioptic detection of intranuclear inclusions is the hallmark of CMV infection.Most gastrointestinal CMV infection responds well to ganciclovir.We present endoscopic and histopathological features of CMV gastritis in a 71 year old woman receiving long-term prednisolone for pemphigus vulgaris.展开更多
Esophagitis dissecans superficialis(EDS)is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining.Although EDS has been reported in association with serious ill...Esophagitis dissecans superficialis(EDS)is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining.Although EDS has been reported in association with serious illnesses and certain medications,the pathophysiological association of autoimmune bullous dermatoses with EDS has gained remarkable attention.Among these dermatoses,pemphigus vulgaris and pemphigoid frequently present with various types of esophageal involvement including EDS.We review the pathophysiology and clinical features of this involvement with the presentation of our experiences.The importance of endoscopic evaluation of this entity is discussed.展开更多
文摘Cytomegalovirus(CMV)has been increasingly recognized as an important common pathogen in an immunocompromised state.The colon and stomach are the most common sites of its gastrointestinal infection. Symptoms of CMV gastritis are usually nonspecific and include epigastric pain,fever,nausea and bleeding. Endoscopic features are quite variable and include macroscopically normal mucosa,diffuse erythema, nodules,pseudotumors,erosions and ulcers.The bioptic detection of intranuclear inclusions is the hallmark of CMV infection.Most gastrointestinal CMV infection responds well to ganciclovir.We present endoscopic and histopathological features of CMV gastritis in a 71 year old woman receiving long-term prednisolone for pemphigus vulgaris.
文摘Esophagitis dissecans superficialis(EDS)is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining.Although EDS has been reported in association with serious illnesses and certain medications,the pathophysiological association of autoimmune bullous dermatoses with EDS has gained remarkable attention.Among these dermatoses,pemphigus vulgaris and pemphigoid frequently present with various types of esophageal involvement including EDS.We review the pathophysiology and clinical features of this involvement with the presentation of our experiences.The importance of endoscopic evaluation of this entity is discussed.
