Structures of membrane protein in solution are different from that in crystal phase. We present the primary results of small angle x-ray scattering （SAXS） resolved topological structures of a light harvesting antenn...Structures of membrane protein in solution are different from that in crystal phase. We present the primary results of small angle x-ray scattering （SAXS） resolved topological structures of a light harvesting antenna membrane protein complex LH2 from photosynthetic bacteria Rhodopseudomonas acidophila in detergent solution for the first time. Our results show that the elliptical shape of the LH2 complex in solution clearly deviates from its circular structure in crystal phase determined by x-ray diffraction. This result provides an insight into the structure and function interplay in LH2.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 10375075, 60321003, and 60438020, the National Key Basic Research and Development Programme of China under Grant No G1998010102, and the Knowledge Innovation Project of Chinese Academy of Sciences under Grant No KJCX2-SW-W14.
文摘Structures of membrane protein in solution are different from that in crystal phase. We present the primary results of small angle x-ray scattering （SAXS） resolved topological structures of a light harvesting antenna membrane protein complex LH2 from photosynthetic bacteria Rhodopseudomonas acidophila in detergent solution for the first time. Our results show that the elliptical shape of the LH2 complex in solution clearly deviates from its circular structure in crystal phase determined by x-ray diffraction. This result provides an insight into the structure and function interplay in LH2.
