Introduction: The clinical manifestations of many diseases vary with age, and older people often do not show typical symptoms of the disease. The present study aims to compare the epidemiological, clinical, therapeuti...Introduction: The clinical manifestations of many diseases vary with age, and older people often do not show typical symptoms of the disease. The present study aims to compare the epidemiological, clinical, therapeutic and evolutionary aspects of elderly patients with COVID-19 compared to young adult patients and to identify risk factors for mortality. Patients and Methods: This was a retrospective single-center analytical study conducted from January 27, 2021 to January 27, 2022 at the COVID-19 Care Center of the Infectious and Tropical Diseases Department of the Bouaké University Teaching Hospital. The study population consisted of all patients aged at least 18 years seen in consultation and/or hospitalized with a positive COVID-19 RT-PCR. The patients were divided into two groups: younger patients (Results: Of a total of 779 patients, 644 (82.7%) were young. The median age of all patients was 41 years (IQR 32 - 54, extreme 18 and 96). Of all the patients 38.5% had a comorbidity. Compared to younger patients, chronic heart disease (61.7% vs 21.5%;p Conclusion: Elderly people with COVID-19 have a different clinical presentation from younger, characterized by more atypical symptoms. Mortality risk factors are age, dyspnoea, impaired consciousness and fever. It is therefore necessary to act on its various factors to improve the prognosis of COVID-19 in this age group.展开更多
Introduction: With the eradication of smallpox in 1980, vaccination against smallpox ceased and there was an upsurge in cases of monkeypox. The objective of this observation is to describe the characteristics of monke...Introduction: With the eradication of smallpox in 1980, vaccination against smallpox ceased and there was an upsurge in cases of monkeypox. The objective of this observation is to describe the characteristics of monkeypox in the vaccinated subject. Case Report: A 45-year-old, heterosexual, rural resident was referred for a rash. The history of the disease revealed signs of acute course marked by headache, asthenia, diffuse myalgia, chest pain, fever and pruritic rash. His background is marked by vaccination against smallpox in 1977, cohabitation with game hunters and domestic animals as well as a notion of contact with a person who presented similar but more generalized signs. The physical examination revealed a conscious patient with good general state, feverish, tachycardic, eupneic presenting skin lesions in the type of striated vesicles more or less umbilical, on the scalp, face, neck, trunk and the upper limbs associated with cervical lymphadenopathy. RT-PCR was performed on a dry swab by rubbing several vesicles and a throat swab proved positive for Monkeypox Virus (MPXV). Management consisted of isolation and symptomatic treatment. The evolution has been favorable. Conclusion: The symptomatology of monkeypox is similar to that of smallpox. Without widely available treatment or prophylaxis, rapid identification of cases is essential. Vaccination of people at risk is an alternative to curb the epidemic. However, the main prevention strategy is to raise awareness of the risk factors.展开更多
文摘Introduction: The clinical manifestations of many diseases vary with age, and older people often do not show typical symptoms of the disease. The present study aims to compare the epidemiological, clinical, therapeutic and evolutionary aspects of elderly patients with COVID-19 compared to young adult patients and to identify risk factors for mortality. Patients and Methods: This was a retrospective single-center analytical study conducted from January 27, 2021 to January 27, 2022 at the COVID-19 Care Center of the Infectious and Tropical Diseases Department of the Bouaké University Teaching Hospital. The study population consisted of all patients aged at least 18 years seen in consultation and/or hospitalized with a positive COVID-19 RT-PCR. The patients were divided into two groups: younger patients (Results: Of a total of 779 patients, 644 (82.7%) were young. The median age of all patients was 41 years (IQR 32 - 54, extreme 18 and 96). Of all the patients 38.5% had a comorbidity. Compared to younger patients, chronic heart disease (61.7% vs 21.5%;p Conclusion: Elderly people with COVID-19 have a different clinical presentation from younger, characterized by more atypical symptoms. Mortality risk factors are age, dyspnoea, impaired consciousness and fever. It is therefore necessary to act on its various factors to improve the prognosis of COVID-19 in this age group.
文摘Introduction: With the eradication of smallpox in 1980, vaccination against smallpox ceased and there was an upsurge in cases of monkeypox. The objective of this observation is to describe the characteristics of monkeypox in the vaccinated subject. Case Report: A 45-year-old, heterosexual, rural resident was referred for a rash. The history of the disease revealed signs of acute course marked by headache, asthenia, diffuse myalgia, chest pain, fever and pruritic rash. His background is marked by vaccination against smallpox in 1977, cohabitation with game hunters and domestic animals as well as a notion of contact with a person who presented similar but more generalized signs. The physical examination revealed a conscious patient with good general state, feverish, tachycardic, eupneic presenting skin lesions in the type of striated vesicles more or less umbilical, on the scalp, face, neck, trunk and the upper limbs associated with cervical lymphadenopathy. RT-PCR was performed on a dry swab by rubbing several vesicles and a throat swab proved positive for Monkeypox Virus (MPXV). Management consisted of isolation and symptomatic treatment. The evolution has been favorable. Conclusion: The symptomatology of monkeypox is similar to that of smallpox. Without widely available treatment or prophylaxis, rapid identification of cases is essential. Vaccination of people at risk is an alternative to curb the epidemic. However, the main prevention strategy is to raise awareness of the risk factors.
