Purpose:To investigate the effect o f refraction error and axial length on retinal nerve fiber l ayer(RNFL)measure-ments as obtained by scanning laser p olarimetry(SLP).Methods:Besides ophthalmological standard examin...Purpose:To investigate the effect o f refraction error and axial length on retinal nerve fiber l ayer(RNFL)measure-ments as obtained by scanning laser p olarimetry(SLP).Methods:Besides ophthalmological standard examination(refractive error,keratometry,vis ual acuity,slit-lamp examination,applanation tonometr y,funduscopy),perimetry,axial length measuremen t by means of ultra-sound,and SLP were performed.Seven ty-five myopic eyes(between-0.75D and -8.5D ),24hyperopic eyes(0.75D -6.5D )and 40emmetropic eyes were investigated.SLP parameters were c ompared in the dif-ferent groups.Results:The statistical analysis of the ab-solute thickness values of SLP revealed highly significant (P<0.01)reductions in average thickness,ellipse av-erage,superior average,inferior a verage,and superior integral in both myopic and hyperopi c eyes in comparison with the emmetropic control eyes.The amount of reduction was between 12.9%(inferior average;myopia)and30.2%(superior integral;hyperopia).There were no significant differences between my opes and hyperopes.A significant linear correlation for many of the SLP parameters with the refractive error(spherical equivalent )but not with axial length was found in both the hyp eropic and the myopic group.Conclusions:Despite a wide i nterindividual range,SLP measurement values decrease with increasing myopia and hyperopia.In clinical practice,such reduced RNFL thickness values should be viewed wi th the necessary cau-tion and additional polarimetric signs for glaucomatous damage should be taken into consideration.展开更多
文摘Purpose:To investigate the effect o f refraction error and axial length on retinal nerve fiber l ayer(RNFL)measure-ments as obtained by scanning laser p olarimetry(SLP).Methods:Besides ophthalmological standard examination(refractive error,keratometry,vis ual acuity,slit-lamp examination,applanation tonometr y,funduscopy),perimetry,axial length measuremen t by means of ultra-sound,and SLP were performed.Seven ty-five myopic eyes(between-0.75D and -8.5D ),24hyperopic eyes(0.75D -6.5D )and 40emmetropic eyes were investigated.SLP parameters were c ompared in the dif-ferent groups.Results:The statistical analysis of the ab-solute thickness values of SLP revealed highly significant (P<0.01)reductions in average thickness,ellipse av-erage,superior average,inferior a verage,and superior integral in both myopic and hyperopi c eyes in comparison with the emmetropic control eyes.The amount of reduction was between 12.9%(inferior average;myopia)and30.2%(superior integral;hyperopia).There were no significant differences between my opes and hyperopes.A significant linear correlation for many of the SLP parameters with the refractive error(spherical equivalent )but not with axial length was found in both the hyp eropic and the myopic group.Conclusions:Despite a wide i nterindividual range,SLP measurement values decrease with increasing myopia and hyperopia.In clinical practice,such reduced RNFL thickness values should be viewed wi th the necessary cau-tion and additional polarimetric signs for glaucomatous damage should be taken into consideration.
