Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal plants.Methods:Antioxidant activity of extracts was evaluated in terms of radical scavengi...Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal plants.Methods:Antioxidant activity of extracts was evaluated in terms of radical scavenging potential(2,2-diphenyl-1-picrylhydrazyl)and β-carotene bleaching assay.Total phenolic contents and flavonoid contents were also measured.Antimicrobial activity of these plants was examined against Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans.Results:The values of IC_(50) ranged from 4.30μg/mL to 486.6μg/mL for the DPPH method,while total antioxidant activity using β-carotene/linoleic acid bleaching assay ranged from 17.03%to 86.13%.It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay(IC_(50)=4.30μg/mL),while Populus trimula,Origanum glandulosum,Centaurea calcitrapa,Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in β-carotene/linoleic acid bleaching assay.Total phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract,respectively.The most interesting antimicrobial activity was obtained from Sysimbrium officinalis,Rhamnus alaternus,Origanum glandulosum,Cupressus sempervirens,Pinus halipensis and Centaurea calcitrapa.Conclusions:The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.展开更多
基金Supported by Algerian Ministry of Higher Education and Scientific Research.
文摘Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal plants.Methods:Antioxidant activity of extracts was evaluated in terms of radical scavenging potential(2,2-diphenyl-1-picrylhydrazyl)and β-carotene bleaching assay.Total phenolic contents and flavonoid contents were also measured.Antimicrobial activity of these plants was examined against Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans.Results:The values of IC_(50) ranged from 4.30μg/mL to 486.6μg/mL for the DPPH method,while total antioxidant activity using β-carotene/linoleic acid bleaching assay ranged from 17.03%to 86.13%.It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay(IC_(50)=4.30μg/mL),while Populus trimula,Origanum glandulosum,Centaurea calcitrapa,Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in β-carotene/linoleic acid bleaching assay.Total phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract,respectively.The most interesting antimicrobial activity was obtained from Sysimbrium officinalis,Rhamnus alaternus,Origanum glandulosum,Cupressus sempervirens,Pinus halipensis and Centaurea calcitrapa.Conclusions:The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.
