Four binol based pyrrole carboxamide chiral receptors has been synthesized and effectively used as a Chirality Conversion Reagent (CCR) for underivatized amino acids. Three points of interactions take place for the co...Four binol based pyrrole carboxamide chiral receptors has been synthesized and effectively used as a Chirality Conversion Reagent (CCR) for underivatized amino acids. Three points of interactions take place for the conversion process. They are the reversible imine formation, the internal resonance assisted Hydrogen Bonding (RAHB) and the additional hydrogen bonds between the amino acids and the heterocylic moiety of the pendant groups. The conversion efficiency of all the receptors was found to be comparable with those of the receptors reported earlier.展开更多
A novel auxillary chiral dimeric binol has been designed,synthesized,and used to enantioselectively recognize 1,2-amino alcohols through the three point of interactions,the reversible imine bond,resonance assisted hyd...A novel auxillary chiral dimeric binol has been designed,synthesized,and used to enantioselectively recognize 1,2-amino alcohols through the three point of interactions,the reversible imine bond,resonance assisted hydrogen bonding and the hydrogen bonding by the additional chiral moiety introduced at the receptor.The enantioselectivities were comparable to those of the previous reported receptors.展开更多
文摘Four binol based pyrrole carboxamide chiral receptors has been synthesized and effectively used as a Chirality Conversion Reagent (CCR) for underivatized amino acids. Three points of interactions take place for the conversion process. They are the reversible imine formation, the internal resonance assisted Hydrogen Bonding (RAHB) and the additional hydrogen bonds between the amino acids and the heterocylic moiety of the pendant groups. The conversion efficiency of all the receptors was found to be comparable with those of the receptors reported earlier.
基金This work is supported by the Fast Track Programme for the Young Scientists of the DST(No.SR/FT/CS-95/2010).
文摘A novel auxillary chiral dimeric binol has been designed,synthesized,and used to enantioselectively recognize 1,2-amino alcohols through the three point of interactions,the reversible imine bond,resonance assisted hydrogen bonding and the hydrogen bonding by the additional chiral moiety introduced at the receptor.The enantioselectivities were comparable to those of the previous reported receptors.
