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Antioxidants as effective remedies at hepatotoxic action of carbon tetrachloride
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作者 Karlen Hovnanyan Vardan Mamikonyan +4 位作者 Anahit Margaryan kristine sargsyan Margarita Hovnanyan Maria Karagyozyan Konstantin Karageuzyan 《Journal of Biophysical Chemistry》 2014年第1期1-4,共4页
The liver, as the central metabolic organ, plays an important role in metabolism of carbohydrates, lipids and proteins. In the environment, there are many hepatotoxic xenobiotics. CCl4 is a free radical toxic for orga... The liver, as the central metabolic organ, plays an important role in metabolism of carbohydrates, lipids and proteins. In the environment, there are many hepatotoxic xenobiotics. CCl4 is a free radical toxic for organelles of hepatocytes. The presented work was studying the character of ultrastructural changes in CCl4-intoxicated hepatocytes as well as the tissue after treatment by grape seed extract (GSE), α-tocopherol (α-T). As a result of cell bioremediation effect and reactions against corruptive factors, the liver has a high regeneration ability. 展开更多
关键词 CCl4 GSE Α-TOCOPHEROL Ultrastructural Changes Intoxicated HEPATOCYTES Electron Microscopy
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