Dear Editor,Dendritic cells(DCs)are the most efficient professional antigen presenting cells that act as sentinels of the immune system and conduct vital functions in the initiation and regulation of innate and adapti...Dear Editor,Dendritic cells(DCs)are the most efficient professional antigen presenting cells that act as sentinels of the immune system and conduct vital functions in the initiation and regulation of innate and adaptive immunities(Wculek et al.,2020).In addition to being critical cellular components in pathogen clearance,DCs are promising targets for improved tumor immunotherapy,vaccine design,and intervention of autoimmune diseases(Nutt and Chopin,2020).DCs can be classified as plasmacytoid DCs(pDCs)and conventional DCs(cDCs)in both mouse and human(Anderson et al.,2018;Nutt and Chopin,2020).展开更多
文摘Dear Editor,Dendritic cells(DCs)are the most efficient professional antigen presenting cells that act as sentinels of the immune system and conduct vital functions in the initiation and regulation of innate and adaptive immunities(Wculek et al.,2020).In addition to being critical cellular components in pathogen clearance,DCs are promising targets for improved tumor immunotherapy,vaccine design,and intervention of autoimmune diseases(Nutt and Chopin,2020).DCs can be classified as plasmacytoid DCs(pDCs)and conventional DCs(cDCs)in both mouse and human(Anderson et al.,2018;Nutt and Chopin,2020).