Based on the characteristics of wireless communication technology and Wireless Sensor Network, this paper studies the well site environmental monitoring system. The relevant hardware and software of the system are des...Based on the characteristics of wireless communication technology and Wireless Sensor Network, this paper studies the well site environmental monitoring system. The relevant hardware and software of the system are designed to monitor the well site environment, thus preventing downhole accidents. The system uses the wireless ZigBee technology as the transmission mode, and combines the virtual instrument technology to design the upper machine interface. The test results show that the system can monitor the outdoor environment in real time. When the environmental parameters exceed the set value, the corresponding location of the LabVIEW interface will send an alarm.展开更多
With the continuous development of industrial technology, the weak current plays an increasingly important role in all fields of life. In order to facilitate the user to carry, the study of contactless weak current me...With the continuous development of industrial technology, the weak current plays an increasingly important role in all fields of life. In order to facilitate the user to carry, the study of contactless weak current measurement technology is also emerging. This article’s design idea is based on two-dimensional reluctance sensor device built non-contact weak current detection system. The system uses the reluctance sensor HMC1002 to collect the current signal and the temperature sensor DS18B20 to compensate the temperature. The signals collected by the reluctance sensor and the temperature sensor are extremely weak. After being amplified by the amplifying circuit, the signal is conducive to subsequent detection and processing. Filter circuit can filter out interference signals to achieve the goal of improving accuracy. After the corresponding algorithm of the microcontroller will convert the signal voltage, easy to read and store, thus designing a non-contact current measurement capable of detecting weak currents and achieving higher accuracy.展开更多
Diet and nutrition have a substantial impact on the human microbiome,and interact with the microbiome,especially gut microbiome,to modulate various diseases and health status.Microbiome research has also guided the nu...Diet and nutrition have a substantial impact on the human microbiome,and interact with the microbiome,especially gut microbiome,to modulate various diseases and health status.Microbiome research has also guided the nutrition field to a more integrative direction,becoming an essential component of the rising area of precision nutrition.In this review,we provide a broad insight into the interplay among diet,nutrition,microbiome,and microbial metabolites for their roles in the human health.Among the microbiome epidemiological studies regarding the associations of diet and nutrition with microbiome and its derived metabolites,we summarize those most reliable findings and highlight evidence for the relationships between diet and disease-associated microbiome and its functional readout.Then,the latest advances of the microbiome-based precision nutrition research and multidisciplinary integration are described.Finally,we discuss several outstanding challenges and opportunities in the field of nutri-microbiome epidemiology.展开更多
Background:Although congenital hypothyroidism(CH)has been widely studied in Western countries,CH incidence at different administrative levels in China during the past decade remains unknown.This study aimed to update ...Background:Although congenital hypothyroidism(CH)has been widely studied in Western countries,CH incidence at different administrative levels in China during the past decade remains unknown.This study aimed to update the incidence and revealed the spatial pattern of CH incidence in the mainland of China,which could be helpful in the planning and implementation of preventative measures.Methods:The data used in our study were derived from 245 newborns screening centers that cover 30 provinces of the Chinese Newborn Screening Information System.Spatial auto-correlation was analyzed by Global Moran I and Getis-Ord Gi statistics at the provincial level.Kriging interpolation methods were applied to estimate a further detailed spatial distribution of CH incidence at city level throughout the mainland of China,and Kulldorff space scanning statistical methods were used to identify the spatial clusters of CH cases at the city level.Results:A total of 91,921,334 neonates were screened from 2013 to 2018 and 42,861 cases of primary CH were identified,yielding an incidence of 4.66 per 10,000 newborns screened(95%confidence interval[CI]:4.62–4.71).Neonates in central(risk ratio[RR]=0.84,95%CI:0.82–0.85)and western districts(RR=0.71,95%CI:0.69–0.73)had lower probability of CH cases compared with the eastern region.The CH incidence indicated a moderate positive global spatial autocorrelation(Global Moran I value=0.394,P<0.05),and the CH cases were significantly clustered in spatial distribution.A most likely city-cluster(log-likelihood ratio[LLR]=588.82,RR=2.36,P<0.01)and 25 secondary city-clusters of high incidence were scanned.The incidence of each province and each city in the mainland of China was estimated by kriging interpolation,revealing the most affected province and city to be Zhejiang Province and Hangzhou city,respectively.Conclusion:This study offers an insight into the space clustering of CH incidence at provincial and city scales.Future work on environmental factors need to focus on the effects of CH occurrence.展开更多
文摘Based on the characteristics of wireless communication technology and Wireless Sensor Network, this paper studies the well site environmental monitoring system. The relevant hardware and software of the system are designed to monitor the well site environment, thus preventing downhole accidents. The system uses the wireless ZigBee technology as the transmission mode, and combines the virtual instrument technology to design the upper machine interface. The test results show that the system can monitor the outdoor environment in real time. When the environmental parameters exceed the set value, the corresponding location of the LabVIEW interface will send an alarm.
文摘With the continuous development of industrial technology, the weak current plays an increasingly important role in all fields of life. In order to facilitate the user to carry, the study of contactless weak current measurement technology is also emerging. This article’s design idea is based on two-dimensional reluctance sensor device built non-contact weak current detection system. The system uses the reluctance sensor HMC1002 to collect the current signal and the temperature sensor DS18B20 to compensate the temperature. The signals collected by the reluctance sensor and the temperature sensor are extremely weak. After being amplified by the amplifying circuit, the signal is conducive to subsequent detection and processing. Filter circuit can filter out interference signals to achieve the goal of improving accuracy. After the corresponding algorithm of the microcontroller will convert the signal voltage, easy to read and store, thus designing a non-contact current measurement capable of detecting weak currents and achieving higher accuracy.
基金This study was funded by the National Key R&D Program of China(No.2022YFA1303900)National Natural Science Foundation of China(Nos.82204161,82073529)+1 种基金the Research Program(No.202208012)of Westlake Laboratory of Life Sciences and BiomedicineChina Postdoctoral Science Foundation(2022M722833,2022M710131).
文摘Diet and nutrition have a substantial impact on the human microbiome,and interact with the microbiome,especially gut microbiome,to modulate various diseases and health status.Microbiome research has also guided the nutrition field to a more integrative direction,becoming an essential component of the rising area of precision nutrition.In this review,we provide a broad insight into the interplay among diet,nutrition,microbiome,and microbial metabolites for their roles in the human health.Among the microbiome epidemiological studies regarding the associations of diet and nutrition with microbiome and its derived metabolites,we summarize those most reliable findings and highlight evidence for the relationships between diet and disease-associated microbiome and its functional readout.Then,the latest advances of the microbiome-based precision nutrition research and multidisciplinary integration are described.Finally,we discuss several outstanding challenges and opportunities in the field of nutri-microbiome epidemiology.
基金supported by a grant from the National Key Research and Development Program of China(No.2017YFC1001700).
文摘Background:Although congenital hypothyroidism(CH)has been widely studied in Western countries,CH incidence at different administrative levels in China during the past decade remains unknown.This study aimed to update the incidence and revealed the spatial pattern of CH incidence in the mainland of China,which could be helpful in the planning and implementation of preventative measures.Methods:The data used in our study were derived from 245 newborns screening centers that cover 30 provinces of the Chinese Newborn Screening Information System.Spatial auto-correlation was analyzed by Global Moran I and Getis-Ord Gi statistics at the provincial level.Kriging interpolation methods were applied to estimate a further detailed spatial distribution of CH incidence at city level throughout the mainland of China,and Kulldorff space scanning statistical methods were used to identify the spatial clusters of CH cases at the city level.Results:A total of 91,921,334 neonates were screened from 2013 to 2018 and 42,861 cases of primary CH were identified,yielding an incidence of 4.66 per 10,000 newborns screened(95%confidence interval[CI]:4.62–4.71).Neonates in central(risk ratio[RR]=0.84,95%CI:0.82–0.85)and western districts(RR=0.71,95%CI:0.69–0.73)had lower probability of CH cases compared with the eastern region.The CH incidence indicated a moderate positive global spatial autocorrelation(Global Moran I value=0.394,P<0.05),and the CH cases were significantly clustered in spatial distribution.A most likely city-cluster(log-likelihood ratio[LLR]=588.82,RR=2.36,P<0.01)and 25 secondary city-clusters of high incidence were scanned.The incidence of each province and each city in the mainland of China was estimated by kriging interpolation,revealing the most affected province and city to be Zhejiang Province and Hangzhou city,respectively.Conclusion:This study offers an insight into the space clustering of CH incidence at provincial and city scales.Future work on environmental factors need to focus on the effects of CH occurrence.
