Background: Coronary artery disease (CAD) is frequently observed in aging end-stage liver disease (ESLD) patients who require orthotopic liver transplantation (OLT). This situation is challenging for both the pa- tien...Background: Coronary artery disease (CAD) is frequently observed in aging end-stage liver disease (ESLD) patients who require orthotopic liver transplantation (OLT). This situation is challenging for both the pa- tients and the medical staff. Methods: We retrospectively studied the case records of 26 ESLD patients with CAD who underwent OLT with total clamping of the inferior vena cava between 2014 and 2018. We analyzed the details of the pre-operative evaluation, intraoperative anesthetic management and post-operative prognosis of these patients. Results: All patients tolerated the anhepatic stage well. Post-reperfusion syndrome (PRS) was observed in 13 patients (50%) and 2 of them were severe but corrected well. ST-segment depression was frequently observed during the anhepatic stage and reperfusion stage. No mortality due to cardiac-related events occurred among the patients during hospitalization. OLT with the modi ed piggyback technique could successfully be performed in ESLD patients with mild and moderate CAD. Conclusions: A thorough evaluation and optimization of recipients, strict monitoring and optimized man-agement of circulation, knowledge of the complicated changes during OLT procedures, and strategies to ameliorate post-reperfusion syndrome favorite the outcomes.展开更多
目的:机器人辅助前列腺癌根治术中需要头低位和气腹,这将严重干扰呼吸顺应性(Crs)。本研究比较机器人辅助腹腔镜前列腺癌根治术在相同气腹压力下不同程度的神经肌肉阻滞对Crs的影响。创新点:不同深度神经肌肉阻滞对机器人辅助前列腺癌...目的:机器人辅助前列腺癌根治术中需要头低位和气腹,这将严重干扰呼吸顺应性(Crs)。本研究比较机器人辅助腹腔镜前列腺癌根治术在相同气腹压力下不同程度的神经肌肉阻滞对Crs的影响。创新点:不同深度神经肌肉阻滞对机器人辅助前列腺癌根治术Crs的观察。方法:将100例接受机器人辅助腹腔镜前列腺癌根治术的患者随机分配到中度神经肌肉阻滞组和深度神经肌肉阻滞组,每组50例。应用罗库溴铵维持神经肌肉阻滞。保持对4个成串刺激1~2个反应为中度神经肌肉阻滞组;对4个成串刺激无反应,而对强直后刺激1~2个反应为深度神经肌肉阻滞组。两组气腹压力均为10 mm Hg。记录麻醉诱导后及气腹0、30、60和90 min的吸气峰值压力、平均压力、Crs和气道阻力。手术结束时对手术条件进行评估。结论:在机器人辅助腹腔镜前列腺癌根治术中,相同的气腹压力下,深度神经肌肉阻滞不能改善Crs和手术条件,但能显著降低术中体动。展开更多
文摘Background: Coronary artery disease (CAD) is frequently observed in aging end-stage liver disease (ESLD) patients who require orthotopic liver transplantation (OLT). This situation is challenging for both the pa- tients and the medical staff. Methods: We retrospectively studied the case records of 26 ESLD patients with CAD who underwent OLT with total clamping of the inferior vena cava between 2014 and 2018. We analyzed the details of the pre-operative evaluation, intraoperative anesthetic management and post-operative prognosis of these patients. Results: All patients tolerated the anhepatic stage well. Post-reperfusion syndrome (PRS) was observed in 13 patients (50%) and 2 of them were severe but corrected well. ST-segment depression was frequently observed during the anhepatic stage and reperfusion stage. No mortality due to cardiac-related events occurred among the patients during hospitalization. OLT with the modi ed piggyback technique could successfully be performed in ESLD patients with mild and moderate CAD. Conclusions: A thorough evaluation and optimization of recipients, strict monitoring and optimized man-agement of circulation, knowledge of the complicated changes during OLT procedures, and strategies to ameliorate post-reperfusion syndrome favorite the outcomes.
基金Project supported by the Zhejiang Province Public Welfare Technology Application Research Project(No.LGF20H010006),China。
文摘目的:机器人辅助前列腺癌根治术中需要头低位和气腹,这将严重干扰呼吸顺应性(Crs)。本研究比较机器人辅助腹腔镜前列腺癌根治术在相同气腹压力下不同程度的神经肌肉阻滞对Crs的影响。创新点:不同深度神经肌肉阻滞对机器人辅助前列腺癌根治术Crs的观察。方法:将100例接受机器人辅助腹腔镜前列腺癌根治术的患者随机分配到中度神经肌肉阻滞组和深度神经肌肉阻滞组,每组50例。应用罗库溴铵维持神经肌肉阻滞。保持对4个成串刺激1~2个反应为中度神经肌肉阻滞组;对4个成串刺激无反应,而对强直后刺激1~2个反应为深度神经肌肉阻滞组。两组气腹压力均为10 mm Hg。记录麻醉诱导后及气腹0、30、60和90 min的吸气峰值压力、平均压力、Crs和气道阻力。手术结束时对手术条件进行评估。结论:在机器人辅助腹腔镜前列腺癌根治术中,相同的气腹压力下,深度神经肌肉阻滞不能改善Crs和手术条件,但能显著降低术中体动。
