Intratumor heterogeneity describes phenomena that cancer cells from a single focal population can be highly diverse in morphology,gene expression,metabolism,motility,proliferation,metastatic potential,and drug sensiti...Intratumor heterogeneity describes phenomena that cancer cells from a single focal population can be highly diverse in morphology,gene expression,metabolism,motility,proliferation,metastatic potential,and drug sensitivity(McGranahan and Swanton,2017).展开更多
基金the National Natural Science Foundation of China(81402582)the Natural Science Foundation of Shanghai(14YF1400600 and 18ZR1404500).
文摘Intratumor heterogeneity describes phenomena that cancer cells from a single focal population can be highly diverse in morphology,gene expression,metabolism,motility,proliferation,metastatic potential,and drug sensitivity(McGranahan and Swanton,2017).