Brains of 41 residents without neurodegenerative diseases in the high-incid ence area of ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii Peninsula of Japan were neuropathologically examined. Neurofibrillary tan...Brains of 41 residents without neurodegenerative diseases in the high-incid ence area of ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii Peninsula of Japan were neuropathologically examined. Neurofibrillary tangles (NFTs) in th e hippocampal area were present in 11 of the 41 cases, but the frequency of NFT -positive cases in each age group was similar to that of the normal Japanese p opulation and far less than that of Guamanians without ALS/PDC.展开更多
文摘Brains of 41 residents without neurodegenerative diseases in the high-incid ence area of ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii Peninsula of Japan were neuropathologically examined. Neurofibrillary tangles (NFTs) in th e hippocampal area were present in 11 of the 41 cases, but the frequency of NFT -positive cases in each age group was similar to that of the normal Japanese p opulation and far less than that of Guamanians without ALS/PDC.
