富血小板血浆对表面多孔性种植体周骨再生的作用

目的:研究钛合金颗粒熔附表面多孔性种植体在植入时应用富血小板血浆(PlateletRichPlasma,PRP),对种植体周围骨再生的影响。方法:钛合金颗粒熔附表面多孔性种植体30枚分别植入5条狗的双侧下颌骨,左侧种植体在植入时局部应用PRP,右侧为对照组。术后3天、1、3、6及12周分别将动物处死,进行组织学和组织形态学分析。结果:术后3天和1周时,两组的组织学表现及骨-种植体接触率(Bone-implantcontact,BIC)均相似。术后3周时,实验组可观察到骨单位已开始形成,两组的骨-种植体接触率具有显著性差异(PRP组为68.11±17.63%,对照组为44.26±31.79%)。术后6周及12周时两组无明显区别。结论:表面多孔性种植体局部应用PRP可更有利于种植体周围早期骨再生,但PRP加快种植体周围骨再生的机制还有待于进一步的研究。

The Stability Analysis of Implants Installed in Osteotomies with Different Types of Controlled Bone Defects

The stability parameters of implants （ITV, ISQ ＆ PTV） according to different sizes of controlled bone defects made in implant osteotomies were analyzed and the correlation among the three kinds of implant stability parameters was tested in this study. 45 tapped screw-type dental implants were inserted in three types of implant osteotomies made in 8 fresh-frozen pig femoral bones： Typel - without coronal bone defect, Type2 - with 3 mm coronal bone defects, and Type3 - with 6 mm coronal bone defects. The insertion torque values, ISQ ＆ PTV of implants were measured and analyzed statistically. It is concluded that the circumferential coronal bone defects statistically influence the primary stability of implants; ITV, ISQ and PTV are suitable and available to detect the peri-implant coronal bone defects in 3 mm increments, and ITV and PTV are more sensitive to coronal cortical bone loss. There was a strong correlation between ITV and ISQ.