Dynaminrelated proteins （DRPs） are key components of the organelle division machineries, functioning as molecular scissors during the fission process. In Arabidopsis, DRP3A and DRP3B are shared by peroxisomal and mi...Dynaminrelated proteins （DRPs） are key components of the organelle division machineries, functioning as molecular scissors during the fission process. In Arabidopsis, DRP3A and DRP3B are shared by peroxisomal and mitochondrial division, whereas the structurallydistinct DRP5B （ARC5） protein is involved in the division of chloroplasts and peroxisomes. Here, we further investigated the roles of DRP3A, DRP3B, and DRP5B in organelle division and plant development. Despite DRP5B＇s lack of stable association with mitochondria, drp5B mutants show defects in mitochondrial division.展开更多
基金supported by grants from the National Science Foundation Arabidopsis 2010 program (MCB 0618335)the Chemical Sciences,Geo sciences and Biosciences Division,Office of Basic Energy Sciences,Office of Science,U.S. Department of Energy (DE-FG02-91ER20021) to J.H
文摘Dynaminrelated proteins （DRPs） are key components of the organelle division machineries, functioning as molecular scissors during the fission process. In Arabidopsis, DRP3A and DRP3B are shared by peroxisomal and mitochondrial division, whereas the structurallydistinct DRP5B （ARC5） protein is involved in the division of chloroplasts and peroxisomes. Here, we further investigated the roles of DRP3A, DRP3B, and DRP5B in organelle division and plant development. Despite DRP5B＇s lack of stable association with mitochondria, drp5B mutants show defects in mitochondrial division.
