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Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse model 被引量:6
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作者 SungYiHong MyunHeeLee +5 位作者 WooJinHyung SungHoonNoh SeungHoChoi kyung sup kim HyunCheolJung JaekyungRoh 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第8期1191-1197,共7页
rAAV mediated endostatin gene therapy has beenexamined as a new method for treating cancer. However,a sustained and high protein delivery is required to achievethe desired therapeutic effects. We evaluated the impacto... rAAV mediated endostatin gene therapy has beenexamined as a new method for treating cancer. However,a sustained and high protein delivery is required to achievethe desired therapeutic effects. We evaluated the impactof topoisomerase inhibitors in rAAV delivered endostatingene therapy in a liver tumor model. 展开更多
关键词 腺相关病毒 拓扑异构酶 肝癌 动物模型 基因疗法 免疫印迹法
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