Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending o...Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending on the spine morphology(flexibility).Using X-ray to characterize AIS curves remains the clinical gold standard whilecompromising the risks of radiation exposure.In previous works,3D ultrasound imaging had proved the reli-ability of the coronal spinal curvature measurement This research aimed at developing a mild AIs clasificationscheme through examining spine flexibility using 3D ultrasound imaging.For the preliminary study,90 mild AIS subjects(21 M and 69 F;Age:14.5±1.7 years old;Cobb:18.2±6.4°)underwent both 3D ultrasound and X-ray scanning on the same day.For each case,a clinician measured Cobbs and denoted major curve as ground truth.Bending Asymmetry Index(BAl)was developed to indicate the presence of a possible structural curve.The curve classification was coded to a modfied Lenke classification for mild cases(m-Lenke).The results of 3D ultrasound classification were evaluated with the X-ray.It was shown that 70.1%of the subjects had identical curve clssification results and 72.0%had the correct major curve detection.Lumbar-dominated curves had distinctive performance(p=0.91,r=0.91)against others.The study demonstrated the possibility of a 3D ultrasound-based method for mild AIS curve classification.Thediscrepancies could be partially explained by the limitations of the ultrasound scanning in proximal thoracicreg ion.Subsequent studies will validate the proposed method with a larger cohort.展开更多
基金This study is partially supported by Research Impact Fund of Hong Kong Research Grant Council(R5017-18)Health and Medical Research Fund of the Hong Kong(04152896).
文摘Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending on the spine morphology(flexibility).Using X-ray to characterize AIS curves remains the clinical gold standard whilecompromising the risks of radiation exposure.In previous works,3D ultrasound imaging had proved the reli-ability of the coronal spinal curvature measurement This research aimed at developing a mild AIs clasificationscheme through examining spine flexibility using 3D ultrasound imaging.For the preliminary study,90 mild AIS subjects(21 M and 69 F;Age:14.5±1.7 years old;Cobb:18.2±6.4°)underwent both 3D ultrasound and X-ray scanning on the same day.For each case,a clinician measured Cobbs and denoted major curve as ground truth.Bending Asymmetry Index(BAl)was developed to indicate the presence of a possible structural curve.The curve classification was coded to a modfied Lenke classification for mild cases(m-Lenke).The results of 3D ultrasound classification were evaluated with the X-ray.It was shown that 70.1%of the subjects had identical curve clssification results and 72.0%had the correct major curve detection.Lumbar-dominated curves had distinctive performance(p=0.91,r=0.91)against others.The study demonstrated the possibility of a 3D ultrasound-based method for mild AIS curve classification.Thediscrepancies could be partially explained by the limitations of the ultrasound scanning in proximal thoracicreg ion.Subsequent studies will validate the proposed method with a larger cohort.
