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CK-MB、hs-CRP和cTnI联合检测病毒性心肌炎患儿的临床价值研究 被引量:15
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作者 赖玉姝 赵衍江 +2 位作者 刘甲辰 王连喜 李素娥 《现代生物医学进展》 CAS 2018年第20期3937-3940,共4页
目的:探讨肌酸激酶同工酶(CK-MB)、超敏C反应蛋白(hs-CRP)和心肌肌钙蛋白I(cTnI)联合检测病毒性心肌炎(VMC)患儿的临床价值。方法:选取2015年7月-2017年3月在本院确诊的70例VMC患儿为观察组,选取同期在本院体检的70例健康儿童为对照组,... 目的:探讨肌酸激酶同工酶(CK-MB)、超敏C反应蛋白(hs-CRP)和心肌肌钙蛋白I(cTnI)联合检测病毒性心肌炎(VMC)患儿的临床价值。方法:选取2015年7月-2017年3月在本院确诊的70例VMC患儿为观察组,选取同期在本院体检的70例健康儿童为对照组,在入院后第2d、第3d、第5d、第7d、第9d和第11d分别测定所有儿童血清CK-MB、cTnI和hs-CRP水平,分析比较三项指标联合检测和单独检测的灵敏度、特异性和准确性。结果:观察组患儿血清CK-MB、cTnI、hs-CRP水平均高于对照组,差异有统计学意义(P<0.05)。观察组患儿CK-MB、cTnI和hs-CRP联合检测的灵敏度和准确性分别为90.12%、93.62%,均高于单独检测,差异有统计学意义(P<0.05),三项指标联合检测的特异性高于hs-CRP单独检测,差异有统计学意义(P<0.05)。检测结果显示,hs-CRP阳性率最高,但在血清中也最先消失,CK-MB次之,cTnI最慢。差异有统计学意义(P<0.05)。结论:采用CK-MB、cTnI和hs-CRP的联合检测,可提高检测VMC患儿的灵敏度和准确性,更具有临床诊断价值。 展开更多
关键词 病毒性心肌炎 心肌肌钙蛋白I 肌酸激酶同工酶 超敏C反应蛋白 临床价值
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Biomechanical comparisons between a new avascular necrosis of femaral head stem based on Chinese patients with avascular necrosis and two other designs 被引量:5
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作者 ZHANG Qiang CHENG Cheng-kung +4 位作者 WEI Hung-wen DONG Xiang CHEN Yi-ting lai yu-shu WANG Yan 《Chinese Medical Journal》 SCIE CAS CSCD 2013年第10期1918-1924,共7页
Background There is a relatively high failure rate of the femoral component in patients with avascular necrosis at the intermediate-term follow-up. Improving the geometrical fit of the femoral stem against the medulla... Background There is a relatively high failure rate of the femoral component in patients with avascular necrosis at the intermediate-term follow-up. Improving the geometrical fit of the femoral stem against the medullary canal may help to provide long-term survivorship of the hip replacement for patients with avascular necrosis. Methods We designed a specific stem, based on morphometric studies of proximal femoral canals in Chinese avascular necrosis patients and evaluated the stem by finite element analyses, comparing the novel stem with two commercially available and commonly used stems. Results The morphometric data from avascular necrosis patients showed specific geometric differences in the proximal femoral canal, including profile curves in both the sagittal and coronary planes than the patients with femoral neck fracture. The shorter stemmed prostheses (FitmoreR and our stem) performed better than the longer stemmed prosthesis (VerSysR). Conclusions This is the first study to investigate the femoral geometries of Chinese avascular necrosis patients. Our stem provides better stability and is theoretically beneficial to bone ingrowth, which may increase the long-term stability and fixation of the implant. 展开更多
关键词 avascular necrosis of femoral head canal shape short-stem femoral prosthesis finite element analysis
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