A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethyl- benzoic acid, 4,4′-bipyridine and cobalt perchlorate anhydrous has been synthesized and characterized in the mixture solvent of water an...A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethyl- benzoic acid, 4,4′-bipyridine and cobalt perchlorate anhydrous has been synthesized and characterized in the mixture solvent of water and alcohol. Crystal data for this complex： monoclinic, space group C2/c, a = 2.3805（8）, b = 1.1464（4）, c = 1.5807（5） nm, y = 128.435（4）°, V= 3.3791（18） nm^3, Dc = 1.246 g/cm^3, Z = 4, F（000） = 1340, final GooF = 1.009, R = 0.0504 and wR = 0.1287. Structural analysis shows that the cobalt ion is coordinated with two nitrogen atoms of one 4,4′- bipyridine molecule and four oxygen atoms from two 2,4,6-trimethylbenzoic acid molecules and two alcohol molecules, giving a distorted octahedral coordination geometry. The result of TG analysis indicates that the title complex is stable till 200 ℃.展开更多
A new copper(Ⅱ)coordination polymer[Cu5(Hpt)5(H2O)2(2,3-PCA)2]n·12nH2O(1)has been successfully synthesized under hydrothermal conditions with copper hydroxide,3-(pyridin-2-yl)-1,2,4-triazole(Hpt)and 2,3-pyridine...A new copper(Ⅱ)coordination polymer[Cu5(Hpt)5(H2O)2(2,3-PCA)2]n·12nH2O(1)has been successfully synthesized under hydrothermal conditions with copper hydroxide,3-(pyridin-2-yl)-1,2,4-triazole(Hpt)and 2,3-pyridinedi-carboxylic acid(2,3-PCA).The structure of the title compound was determined by X-ray diffraction analyses,elemental analyses and IR spectrum.The architecture of 1 consists of one-dimensional sandwich-like chains which are connected by extensive hydrogen bonding interactions.The solid-state photoluminescence displays an obvious emission band at 384 nm upon excitation at 340 nm.In addition,electrochemistry property has also been studied.展开更多
A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethylbenzoic acid, 1,10-phenanthroline and cobalt perchlorate anhydrous has been synthesized in the solvent mixture of water/methanol and charac...A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethylbenzoic acid, 1,10-phenanthroline and cobalt perchlorate anhydrous has been synthesized in the solvent mixture of water/methanol and characterized. Crystal data for this complex： tetragonal, space group I41, a = 2.0356（2）, c = 1.3779（3） nm, V= 5.7096（15） nm^3, Mr= 581.51,μ（MoKa） = 0.644, Dc = 1.353 g/cm^3, Z = 8, F（000） = 2424, final S = 1.005, R = 0.0404 and wR = 0.0865. The crystal structure shows that the cobalt ion is coordinated with two nitrogen atoms of one 1,10-phenanthroline molecule, three oxygen atoms from three 2,4,6-trimethylbenzoic acid molecules and one water molecule, giving a distorted octahedral coordination geometry. The result of TG analysis indicates that the title complex is stable till 200 ℃.展开更多
A new dinuclear manganese complex [Mn2（L）2（2,2＇-bipy）2（H2O）512·3H2O has been synthesized with MnSO4·H2O, 2,2＇-bibenzoic acid （H2L） and 2,2＇-bipyridine（2,2＇-bipy） in the mixed solvent ethanol an...A new dinuclear manganese complex [Mn2（L）2（2,2＇-bipy）2（H2O）512·3H2O has been synthesized with MnSO4·H2O, 2,2＇-bibenzoic acid （H2L） and 2,2＇-bipyridine（2,2＇-bipy） in the mixed solvent ethanol and water. It crystallizes in monoclinic, space group Pi with a = 9.9944（10）, b = 21.939（2）, c = 25.628（3） A, a = 108.429（3）, β = 100.613（4）, 7 = 102.821（3）°, V = 4997.9（9） A3, Dc= 1.355 g/cm^3, Z = 2, F（000） = 2108, GOOF = 1.074, the R= 0.0626 and wR= 0.1531. The structure of the complex contains two [Mn2（L）2（2,2＇-bipy）2] units, ten coordinated H2O molecules and three uncoordinated H2O molecules. The fluorescence, thermal stability and magnetic properties of the complex were investigated.展开更多
A new copper（Ⅱ） complex [Cu2（MNA）2（2,2‘-bipy）2]·2.5H2 O with methy-5-norbornene-2,3-dicarboxylic acid（MNA） and 2,2’-bipyridine as ligands has been synthesized in the mixed solvents of DMF and water.It ...A new copper（Ⅱ） complex [Cu2（MNA）2（2,2‘-bipy）2]·2.5H2 O with methy-5-norbornene-2,3-dicarboxylic acid（MNA） and 2,2’-bipyridine as ligands has been synthesized in the mixed solvents of DMF and water.It crystallizes in monoclinic,space group P 1,with a = 10.4191（11）,b = 12.8883（13）,c = 16.1114（16） A,α = 70.8090（10）,β = 80.568（2）,γ = 77.440（2）o,V = 1984.3（4） A^3,Dc = 1.551 g/cm^3,Z = 2,F（000） = 962,the final GOOF = 1.051,R = 0.0431 and w R= 0.0980.The crystal structure shows that the whole molecule consists of two independent dinuclear units,in which two copper ions are bridged by two μ2-η^1：η^0 3-carboxylate groups of MNA^2-.The coordination environment of Cu（Ⅱ） ion is Cu O3N2,giving a distorted square pyramidal geometry.The spectroscopic characterization,thermal stability and magnetic properties of the complex were investigated.展开更多
目的:现有研究显示,原发性痛风和高尿酸血症是一类多基因遗传性疾病,是遗传因素和环境因素共同作用的结果。但目前对痛风和高尿酸血症的遗传易感性研究尚不完善,还不能预测哪些人群易患痛风和高尿酸血症。全基因组关联分析(Genome-wide ...目的:现有研究显示,原发性痛风和高尿酸血症是一类多基因遗传性疾病,是遗传因素和环境因素共同作用的结果。但目前对痛风和高尿酸血症的遗传易感性研究尚不完善,还不能预测哪些人群易患痛风和高尿酸血症。全基因组关联分析(Genome-wide association study,GWAS)是近年来发展起来的用于识别、鉴定复杂性疾病致病易感基因的手段,通过对病人和正常对照人群的筛查,结合计算机技术和统计分析手段,可从整个基因组变异来识别、鉴定微效基因及其与相关疾病的相互作用。笔者对近几年发现的尿酸相关基因进行总结分类,为进一步认识痛风和高尿酸血症的分子机制提供依据,为进一步深入研究痛风和高尿酸血症的病因提供有益参考。展开更多
基金Project supported by the Natural Science Foundation of Hunan Province (No. 05JJ30016), Foundation of Education Committee of Hunan Province (05C001), Foundation of Hengyang Sci. & Tech. Bureau (2005Cg10-23) and Fund for Distinguished Young Cadreman of Hengyang Normal University(2006)
文摘A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethyl- benzoic acid, 4,4′-bipyridine and cobalt perchlorate anhydrous has been synthesized and characterized in the mixture solvent of water and alcohol. Crystal data for this complex： monoclinic, space group C2/c, a = 2.3805（8）, b = 1.1464（4）, c = 1.5807（5） nm, y = 128.435（4）°, V= 3.3791（18） nm^3, Dc = 1.246 g/cm^3, Z = 4, F（000） = 1340, final GooF = 1.009, R = 0.0504 and wR = 0.1287. Structural analysis shows that the cobalt ion is coordinated with two nitrogen atoms of one 4,4′- bipyridine molecule and four oxygen atoms from two 2,4,6-trimethylbenzoic acid molecules and two alcohol molecules, giving a distorted octahedral coordination geometry. The result of TG analysis indicates that the title complex is stable till 200 ℃.
基金Supported by the Natural Science Foundation of Hunan Province(2019JJ60021,2019JJ50013)the Scientific Research Found of Education Department of Hunan Province(17A049)Industry and Research Key Project of Hengyang City(2018KJ016,HXKJ201942,2017KJ193)
文摘A new copper(Ⅱ)coordination polymer[Cu5(Hpt)5(H2O)2(2,3-PCA)2]n·12nH2O(1)has been successfully synthesized under hydrothermal conditions with copper hydroxide,3-(pyridin-2-yl)-1,2,4-triazole(Hpt)and 2,3-pyridinedi-carboxylic acid(2,3-PCA).The structure of the title compound was determined by X-ray diffraction analyses,elemental analyses and IR spectrum.The architecture of 1 consists of one-dimensional sandwich-like chains which are connected by extensive hydrogen bonding interactions.The solid-state photoluminescence displays an obvious emission band at 384 nm upon excitation at 340 nm.In addition,electrochemistry property has also been studied.
基金Project supported by the Natural Science Foundation of Hunan Province (No. 05JJ30016), Foundation of Education Committee of Hunan Province (05C001), Foundation of Hengyang Sci. & Tech. Bureau (2005Cg10-23) and Fund for Distinguished Young Scholars of Hengyang Normal University (No. 2003C16)
文摘A one-dimensional chain cobalt（Ⅱ） coordination polymer with 2,4,6-trimethylbenzoic acid, 1,10-phenanthroline and cobalt perchlorate anhydrous has been synthesized in the solvent mixture of water/methanol and characterized. Crystal data for this complex： tetragonal, space group I41, a = 2.0356（2）, c = 1.3779（3） nm, V= 5.7096（15） nm^3, Mr= 581.51,μ（MoKa） = 0.644, Dc = 1.353 g/cm^3, Z = 8, F（000） = 2424, final S = 1.005, R = 0.0404 and wR = 0.0865. The crystal structure shows that the cobalt ion is coordinated with two nitrogen atoms of one 1,10-phenanthroline molecule, three oxygen atoms from three 2,4,6-trimethylbenzoic acid molecules and one water molecule, giving a distorted octahedral coordination geometry. The result of TG analysis indicates that the title complex is stable till 200 ℃.
基金Supported by the Key Project of Science and Technology Plan of Hunan Province(2012FJ2002)Science and Technology Committee of Hengyang(2013KG77)the Construct Program of the Key Discipline in Hunan Province
文摘A new dinuclear manganese complex [Mn2（L）2（2,2＇-bipy）2（H2O）512·3H2O has been synthesized with MnSO4·H2O, 2,2＇-bibenzoic acid （H2L） and 2,2＇-bipyridine（2,2＇-bipy） in the mixed solvent ethanol and water. It crystallizes in monoclinic, space group Pi with a = 9.9944（10）, b = 21.939（2）, c = 25.628（3） A, a = 108.429（3）, β = 100.613（4）, 7 = 102.821（3）°, V = 4997.9（9） A3, Dc= 1.355 g/cm^3, Z = 2, F（000） = 2108, GOOF = 1.074, the R= 0.0626 and wR= 0.1531. The structure of the complex contains two [Mn2（L）2（2,2＇-bipy）2] units, ten coordinated H2O molecules and three uncoordinated H2O molecules. The fluorescence, thermal stability and magnetic properties of the complex were investigated.
基金Supported by the Natural Science Foundation of Hunan Province(No.11JJ9006)Key Project of Science and Technology Plan of Hunan Province(2012FJ2002)the Construct Program of the Key Discipline in Hunan Province
文摘A new copper（Ⅱ） complex [Cu2（MNA）2（2,2‘-bipy）2]·2.5H2 O with methy-5-norbornene-2,3-dicarboxylic acid（MNA） and 2,2’-bipyridine as ligands has been synthesized in the mixed solvents of DMF and water.It crystallizes in monoclinic,space group P 1,with a = 10.4191（11）,b = 12.8883（13）,c = 16.1114（16） A,α = 70.8090（10）,β = 80.568（2）,γ = 77.440（2）o,V = 1984.3（4） A^3,Dc = 1.551 g/cm^3,Z = 2,F（000） = 962,the final GOOF = 1.051,R = 0.0431 and w R= 0.0980.The crystal structure shows that the whole molecule consists of two independent dinuclear units,in which two copper ions are bridged by two μ2-η^1：η^0 3-carboxylate groups of MNA^2-.The coordination environment of Cu（Ⅱ） ion is Cu O3N2,giving a distorted square pyramidal geometry.The spectroscopic characterization,thermal stability and magnetic properties of the complex were investigated.
文摘目的:现有研究显示,原发性痛风和高尿酸血症是一类多基因遗传性疾病,是遗传因素和环境因素共同作用的结果。但目前对痛风和高尿酸血症的遗传易感性研究尚不完善,还不能预测哪些人群易患痛风和高尿酸血症。全基因组关联分析(Genome-wide association study,GWAS)是近年来发展起来的用于识别、鉴定复杂性疾病致病易感基因的手段,通过对病人和正常对照人群的筛查,结合计算机技术和统计分析手段,可从整个基因组变异来识别、鉴定微效基因及其与相关疾病的相互作用。笔者对近几年发现的尿酸相关基因进行总结分类,为进一步认识痛风和高尿酸血症的分子机制提供依据,为进一步深入研究痛风和高尿酸血症的病因提供有益参考。
