期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
新型织物表面摩擦性能测试系统 被引量:4
1
作者 李莎 赵岩 +3 位作者 左召光 高禄 李大川 刘皓 《天津工业大学学报》 CAS 北大核心 2020年第1期43-47,56,共6页
针对现有织物表面摩擦性能测试仪器的进口设备价格昂贵、国内外仪器不能反映正压力变化和不能多方向测试的现状,依据力学测试法原理开发了一种高稳定性、高精度和低成本的新型织物表面摩擦性能测试系统;通过测试摩擦力与正压力,计算得... 针对现有织物表面摩擦性能测试仪器的进口设备价格昂贵、国内外仪器不能反映正压力变化和不能多方向测试的现状,依据力学测试法原理开发了一种高稳定性、高精度和低成本的新型织物表面摩擦性能测试系统;通过测试摩擦力与正压力,计算得出摩擦因数,能够实现动态的正压力的变化测试和多方向的测试。结果表明:使用纯棉、涤棉和涤纶织物经过5次重复性测试,其摩擦因数的平均值依次在0.23、0.17、0.16附近微小波动,仪器具有良好的稳定性和可重复性;与KES-FB4织物风格仪测试系统的对比试验中,2种仪器测得的纯棉织物的摩擦因数曲线几乎重合,其平均值围绕0.23附近微小波动。本仪器测试了正压力的变化,摩擦因数值比KES-FB4测试得到的摩擦因数值趋于更稳定。 展开更多
关键词 织物 摩擦因数 稳定性 重复性 精确性
下载PDF
智能服装的应用及发展 被引量:3
2
作者 李莎 高禄 +2 位作者 赵岩 李大川 钱晓明 《纺织科学与工程学报》 CAS 2020年第4期81-87,共7页
为了促进智能服装的发展,介绍了近年国内外智能服装的功能和应用领域,探讨了目前智能服装存在的一些问题,并展望了智能服装未来的发展趋势。
关键词 智能服装 功能 应用
下载PDF
Baicalin Antagonizes Prostate Cancer Stemness via Inhibiting Notch1/NF-κB Signaling Pathway 被引量:2
3
作者 WU Ming-hui WU Kun +3 位作者 ZHU Yuan-bing li da-chuan YANG Huan ZENG Hong 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2023年第10期914-923,共10页
Objective To investigate the molecular mechanisms underlying the effect of baicalin on prostate cancer(PCa)progression both in vivo and in vitro.Methods The in situ PCa stem cells(PCSCs)-injected xenograft tumor model... Objective To investigate the molecular mechanisms underlying the effect of baicalin on prostate cancer(PCa)progression both in vivo and in vitro.Methods The in situ PCa stem cells(PCSCs)-injected xenograft tumor models were established in BALB/c nude mice.Tumor volume and weight were respectively checked after baicalin(100 mg/kg)treatment.Hematoxylin-eosin(HE)staining was used to observe the growth arrest and cell necrosis.mRNA expression levels of acetaldehyde dehydrogenase 1(ALDH1),CD44,CD133 and Notch1 were determined by reverse transcription-polymerase chain reaction.Protein expression levels of ALDH1,CD44,CD133,Notch1,nuclear factorκB(NF-κB)P65 and NF-κB p-P65 were detected by Western blot.Expression and subcellular location of ALDH1,CD44,CD133,Notch1 and NF-κB p65 were detected by immunofluorescence analysis.In vitro,cell cycle distribution and cell apoptosis of PC3 PCSCs was assessed by flow cytometry after baicalin(125µmol/L)treatment.The migration and invasion abilities of PCSCs were assessed using Transwell assays.Transmission electron microscopy scanning was utilized to observe the structure and autophagosome formation of baicalin-treated PCSCs.In addition,PCSCs were infected with lentiviruses expressing human Notch1.Results Compared with the control group,the tumor volume and weight were notably reduced in mice treated with 100 mg/kg baicalin(P<0.05 or P<0.01).Histopathological analysis showed that baicalin treatment significantly inhibited cell proliferation and promoted cell apoptosis.Furthermore,baicalin treatment reduced mRNA and protein expression levels of CD44,CD133,ALDH1,and Notch1 as well as the protein expression of NF-κB p-P65 in the xenograft tumor(P<0.01).In vitro,the cell proliferation of PCSCs was significantly attenuated after treatment with 125µmol/L baicalin for 72 h(P<0.01).The cell migration and invasion rates were decreased following treatment with baicalin for 48 and 72 h(P<0.01).Baicalin notably induced cell apoptosis and seriously damaged the structure of PCSCs.The mRNA and protein expressions of CD133,CD44,ALDH1 and Notch1 in PCSCs were significantly downregulated following baicalin treatment(P<0.01).Importantly,the inhibitory effects of baicalin on PCa progression and stemness were reversed by Notch1 overexpression(P<0.05 or P<0.01).Conclusion Mechanistically,baicalin exhibited a potential therapeutic effect on PCa via inhibiting the Notch1/NF-κB signaling pathway and its mediated cancer stemness. 展开更多
关键词 BAICALIN prostate cancer cancer stemness Notch1/nuclear factorκB signaling
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部