中西医结合疗法联合护理干预治疗下肢深静脉血栓形成临床研究

目的:观察中西医结合疗法联合护理干预治疗下肢深静脉血栓形成的效果。方法:选取下肢深静脉血栓形成患者56例,按随机数字表法分为对照组和观察组各28例。对照组采用西医治疗,观察组采用中西医结合治疗并配合护理干预。比较2组治疗前后凝血功能、患肢平面周径、血管再通情况及并发症发生情况。结果:治疗前,2组活化部分凝血活酶时间(PT)、活化部分凝血酶原时间(APTT)、D二聚体(D-D)水平比较,差异无统计学意义(P>0.05)。治疗后,2组PT、APTT水平较治疗前升高,D-D水平较治疗前降低;且观察组PT、APTT水平高于对照组,而D-D水平低于对照组;差异均有统计学意义(P<0.05)。治疗前,2组患肢大腿、小腿平面周径比较,差异无统计学意义(P>0.05)。治疗后,2组患肢大腿、小腿平面周径均较治疗前降低,且观察组患肢大腿、小腿平面周径均低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组血管再通率高于对照组,而并发症发生率低于对照组,差异均有统计学意义(P<0.05)。结论:中西医结合疗法联合护理干预治疗下肢深静脉血栓形成,可有效改善患者凝血功能,缩小患肢平面周径,提高血管再通率,减少并发症。

Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis

Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (Ria) for training samples is 99.8% and Ria by leave one out cross validation is 99.5%. Both Ria of 99.8% for training samples and Ria of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external Ria for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.

支气管扩张合并慢性阻塞性肺疾病的研究进展

支气管扩张和慢性阻塞性肺疾病是呼吸系统常见的两种疾病，两者可单独出现，也可同时存在。当合并存在时即支气管扩张症一慢性阻塞性肺疾病重叠综合征（BCOS）。目前国内外对该疾病研究还比较欠缺，其发病机制、流行病学、危险因素及诊疗方案等尚不明确，临床上缺乏统一诊疗指南，本文就BCOS目前的研究进展进行综述，为临床提供参考。