We report the detailed information of a purely elastic instability and its mixing enhancement effect in a viscoelastic fluid flow driven by a constant pressure gradient along a curvilinear channel obtained for the fir...We report the detailed information of a purely elastic instability and its mixing enhancement effect in a viscoelastic fluid flow driven by a constant pressure gradient along a curvilinear channel obtained for the first time from the three-dimensional direct numerical simulations(DNSs)of this kind of flow geometry.Three-dimensional unstable flow structures similar to those visualized in experiments are realized through the DNSs.The inception of elastic instability,conformation of microstructures,statistical and dynamic information of velocity field and the mixing enhancement effect caused by elastic instability are then discussed.展开更多
目的:对比结肠癌患者接受单孔加一腹腔镜手术(Single-Incision Plus One Port Laparoscopic Surgery,SILS+1)与常规5孔腹腔镜手术的治疗效果。方法:收集2021年3月~2022年2月在本院胃肠外科接受结肠癌根治术患者为研究对象,根据手术方式...目的:对比结肠癌患者接受单孔加一腹腔镜手术(Single-Incision Plus One Port Laparoscopic Surgery,SILS+1)与常规5孔腹腔镜手术的治疗效果。方法:收集2021年3月~2022年2月在本院胃肠外科接受结肠癌根治术患者为研究对象,根据手术方式将其分为观察组(接受SILS+1,n=53)和对照组(接受5孔腹腔镜手术,n=55);首先分析比较两种手术方法围手术期指标和实验室如白蛋白、总蛋白、C-反应蛋白(C-reactive protein,CRP)等;再比较两组术后数字疼痛强度量表(numerical rating scale,NRS)评分,并发症和随访结果。结果:两组术中出血量、淋巴结清扫数量和pTNM分期、首次进食时间无差异(P>0.05);接受SILS+1患者首次下床、排气、住院时间均低于对照组,手术时间长于对照组(P<0.05);两组患者术前总蛋白、白蛋白、去甲肾上腺素(Norepinephrine,NE)、CRP、白细胞介素-6(Interleukin-6,IL-6)水平无差异(P>0.05),术后总蛋白、白蛋白较术前下降,CRP、IL-6、NE较术前升高(P<0.05),组间差异显著(P<0.05);术后第12、24、48h的NRS评分,观察组均低于对照组(P<0.05);观察组和对照组并发症发生率(3.77%,5.45%)、2年总生存率(94.33%,92.72%)和复发率(21.56%,23.63%),相比无统计学差异(P>0.05)。结论:与常规5孔腹腔镜手术相比,SILS+1在结肠癌根治术中具备术后康复快、痛感低、炎症反应轻和住院时间短等优势,长期疗效与传统腹腔镜手术(CLS)相比无差异。展开更多
基金Supported by National Natural Science Foundation of China under Grant No 51076036the Foundation for Innovative Research Groups of the National Natural Science Foundation of China under Grant No 51121004+1 种基金the Fundamental Research Funds for the Central Universities under Grant No HIT.BRET1.2010008the Japan Society for the Promotion of Science(JSPS)Research Fellowship.
文摘We report the detailed information of a purely elastic instability and its mixing enhancement effect in a viscoelastic fluid flow driven by a constant pressure gradient along a curvilinear channel obtained for the first time from the three-dimensional direct numerical simulations(DNSs)of this kind of flow geometry.Three-dimensional unstable flow structures similar to those visualized in experiments are realized through the DNSs.The inception of elastic instability,conformation of microstructures,statistical and dynamic information of velocity field and the mixing enhancement effect caused by elastic instability are then discussed.
文摘目的:对比结肠癌患者接受单孔加一腹腔镜手术(Single-Incision Plus One Port Laparoscopic Surgery,SILS+1)与常规5孔腹腔镜手术的治疗效果。方法:收集2021年3月~2022年2月在本院胃肠外科接受结肠癌根治术患者为研究对象,根据手术方式将其分为观察组(接受SILS+1,n=53)和对照组(接受5孔腹腔镜手术,n=55);首先分析比较两种手术方法围手术期指标和实验室如白蛋白、总蛋白、C-反应蛋白(C-reactive protein,CRP)等;再比较两组术后数字疼痛强度量表(numerical rating scale,NRS)评分,并发症和随访结果。结果:两组术中出血量、淋巴结清扫数量和pTNM分期、首次进食时间无差异(P>0.05);接受SILS+1患者首次下床、排气、住院时间均低于对照组,手术时间长于对照组(P<0.05);两组患者术前总蛋白、白蛋白、去甲肾上腺素(Norepinephrine,NE)、CRP、白细胞介素-6(Interleukin-6,IL-6)水平无差异(P>0.05),术后总蛋白、白蛋白较术前下降,CRP、IL-6、NE较术前升高(P<0.05),组间差异显著(P<0.05);术后第12、24、48h的NRS评分,观察组均低于对照组(P<0.05);观察组和对照组并发症发生率(3.77%,5.45%)、2年总生存率(94.33%,92.72%)和复发率(21.56%,23.63%),相比无统计学差异(P>0.05)。结论:与常规5孔腹腔镜手术相比,SILS+1在结肠癌根治术中具备术后康复快、痛感低、炎症反应轻和住院时间短等优势,长期疗效与传统腹腔镜手术(CLS)相比无差异。
