The effects of cadmium stress on the growth, antioxidative enzymes and lipid peroxidation in two kenaf plants, Fuhong 991 and ZM412, were analysed under control （0.5-strength Hoagland＇s nutrient solution） or five l...The effects of cadmium stress on the growth, antioxidative enzymes and lipid peroxidation in two kenaf plants, Fuhong 991 and ZM412, were analysed under control （0.5-strength Hoagland＇s nutrient solution） or five levels of cadmium stress （0.5- strength Hoagland＇s nutrient solution containing different concentrations of Cd2＋）. The leaves and roots of control and cadmium-stressed plants were harvested after 3 wk. At the same Cd concentration, the Cd tolerance index of Fuhong 991 was higher than that of ZM412, indicating that Fuhong 991 may be more tolerant to Cd than ZM412. The superoxide dismutase （SOD）, catalase activity （CAT） and peroxidase （POD） activities fluctuated in the leaves of the Cd-stressed plants compared to the control, whereas the glutathione reductase activity （GR） was much larger than the control for Fuhong 991, ensuring that sufficient quantities of GSH were available to respond to the cadmium stress. In comparison to the control, the dynamic tendency of the SOD, CAT and POD activities in roots of the Cd-stressed plants all increased and then declined, but the POD activity of Fuhong 991 remained nearly unchanged at all of the stress levels. The increase in the enzyme activities demonstrated that Fuhong 991 was more tolerant to cadmium than ZM 412. The lipid peroxidation was enhanced only in the leaves of Cd-stressed ZM 412. These findings indicated that antioxidative activities may play important roles in Cd-stressed Fuhong 991 and ZM 412 and that the leaf and root cell membranes of Fuhong 991 have a greater stability than those of ZM 412. For pollution monitoring purposes, the GR activity in the roots and leaves may serve as a biomarker of Cd for Fuhong 991, whereas lipid peroxidation may serve as biomarker for ZM 412.展开更多
目的:观察枳实薤白桂枝汤治疗稳定性冠状动脉粥样硬化性心脏病(简称冠心病)痰阻心脉证的临床疗效。方法:将68例稳定性冠心病患者按照随机数字表法分为对照组和观察组,每组各34例。对照组给予常规西药治疗,观察组在对照组的基础上加用枳...目的:观察枳实薤白桂枝汤治疗稳定性冠状动脉粥样硬化性心脏病(简称冠心病)痰阻心脉证的临床疗效。方法:将68例稳定性冠心病患者按照随机数字表法分为对照组和观察组,每组各34例。对照组给予常规西药治疗,观察组在对照组的基础上加用枳实薤白桂枝汤治疗。比较两组患者的临床疗效及治疗前后中医证候评分、西雅图心绞痛量表(seattle anginaquestionnaire,SAQ)评分、简明健康状况调查表(the mos item short from health survey,SF-36)评分、超敏C反应蛋白(hs-C reactive protein,hs-CRP)、超氧化物歧化酶(superoxide dismutase,SOD)、同型半胱氨酸(homocysteine,Hcy)、血浆致动脉硬化指数(plasma atherogenic index,AIP)变化情况。结果:观察组有效率为94.12%,对照组有效率为76.47%,两组有效率比较,差异具有统计学意义(P<0.05)。两组治疗后中医证候评分低于本组治疗前,且观察组治疗后低于对照组治疗后,差异具有统计学意义(P<0.05)。两组治疗后SAQ评分、SF-36评分均高于本组治疗前,且观察组治疗后高于对照组治疗后,差异具有统计学意义(P<0.05)。两组治疗后hs-CRP、Hcy、AIP低于本组治疗前,SOD高于本组治疗前;观察组治疗后hs-CRP、Hcy、AIP均低于对照组,SOD高于对照组,差异具有统计学意义(P<0.05)。结论:枳实薤白桂枝汤治疗稳定性冠心病痰阻心脉证,可有效缓解患者慢性炎症反应,抑制动脉粥样硬化进程,增强机体对氧化物的清除能力,提高患者生活质量。展开更多
目的:观察桂姜枳实汤加味联合常规西药治疗冠状动脉粥样硬化性心脏病(简称冠心病)合并慢性心力衰竭的临床疗效。方法:将62例冠心病合并慢性心力衰竭患者按照随机数字表法分为对照组和观察组,每组各31例。对照组给予常规西药治疗,观察组...目的:观察桂姜枳实汤加味联合常规西药治疗冠状动脉粥样硬化性心脏病(简称冠心病)合并慢性心力衰竭的临床疗效。方法:将62例冠心病合并慢性心力衰竭患者按照随机数字表法分为对照组和观察组,每组各31例。对照组给予常规西药治疗,观察组在对照组治疗的基础上联合桂姜枳实汤加味治疗。比较两组患者的临床疗效及治疗前后中医证候评分、超声心动图指标[左室舒张末期内径(left ventricular end diastolic diameter,LVEDD)、左室收缩末期内径(Left ventricular end systolic diameter,LVESD)、左心室射血分数(left ventricular ejection fraction,LVEF)]、心率变异性指标、6分钟步行试验距离、明尼苏达心力衰竭生活质量问卷(minnesota living with heart failure questionnaire,MLHFQ)评分的变化情况。结果:观察组有效率为90.32%,对照组有效率为70.97%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后中医证候评分均低于本组治疗前,且观察组治疗后中医证候评分均低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后LVEDD、LVESD低于本组治疗前,LVEF高于本组治疗前,观察组治疗后LVEDD、LVESD低于对照组,LVEF高于对照组,差异均有统计学意义(P<0.05)。两组患者治疗后心率变异性水平均高于本组治疗前,且观察组治疗后心率变异性水平高于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后6分钟步行试验距离高于本组治疗前,MLHFFQ评分低于本组治疗前,观察组治疗后6分钟步行试验距离高于对照组,MLHFFQ评分低于对照组,差异具有统计学意义(P<0.05)。结论:桂姜枳实汤加味联合西药治疗冠心病合并慢性心力衰竭,可改善患者的临床症状、心功能及心率变异性水平。展开更多
基金funded by the Project of Fiber Crops Industrial System Construction in China (CARS-19-E06)the Project for Constructing Observations Station of Scientific Experiment of Jute and Kenaf in the South East of China, Ministry of Agriculture of China (2011.9)the Construction of Germplasm Resources Plat form for BastFiber Crops in Fujian, China (2010N2002)
文摘The effects of cadmium stress on the growth, antioxidative enzymes and lipid peroxidation in two kenaf plants, Fuhong 991 and ZM412, were analysed under control （0.5-strength Hoagland＇s nutrient solution） or five levels of cadmium stress （0.5- strength Hoagland＇s nutrient solution containing different concentrations of Cd2＋）. The leaves and roots of control and cadmium-stressed plants were harvested after 3 wk. At the same Cd concentration, the Cd tolerance index of Fuhong 991 was higher than that of ZM412, indicating that Fuhong 991 may be more tolerant to Cd than ZM412. The superoxide dismutase （SOD）, catalase activity （CAT） and peroxidase （POD） activities fluctuated in the leaves of the Cd-stressed plants compared to the control, whereas the glutathione reductase activity （GR） was much larger than the control for Fuhong 991, ensuring that sufficient quantities of GSH were available to respond to the cadmium stress. In comparison to the control, the dynamic tendency of the SOD, CAT and POD activities in roots of the Cd-stressed plants all increased and then declined, but the POD activity of Fuhong 991 remained nearly unchanged at all of the stress levels. The increase in the enzyme activities demonstrated that Fuhong 991 was more tolerant to cadmium than ZM 412. The lipid peroxidation was enhanced only in the leaves of Cd-stressed ZM 412. These findings indicated that antioxidative activities may play important roles in Cd-stressed Fuhong 991 and ZM 412 and that the leaf and root cell membranes of Fuhong 991 have a greater stability than those of ZM 412. For pollution monitoring purposes, the GR activity in the roots and leaves may serve as a biomarker of Cd for Fuhong 991, whereas lipid peroxidation may serve as biomarker for ZM 412.
文摘目的:观察枳实薤白桂枝汤治疗稳定性冠状动脉粥样硬化性心脏病(简称冠心病)痰阻心脉证的临床疗效。方法:将68例稳定性冠心病患者按照随机数字表法分为对照组和观察组,每组各34例。对照组给予常规西药治疗,观察组在对照组的基础上加用枳实薤白桂枝汤治疗。比较两组患者的临床疗效及治疗前后中医证候评分、西雅图心绞痛量表(seattle anginaquestionnaire,SAQ)评分、简明健康状况调查表(the mos item short from health survey,SF-36)评分、超敏C反应蛋白(hs-C reactive protein,hs-CRP)、超氧化物歧化酶(superoxide dismutase,SOD)、同型半胱氨酸(homocysteine,Hcy)、血浆致动脉硬化指数(plasma atherogenic index,AIP)变化情况。结果:观察组有效率为94.12%,对照组有效率为76.47%,两组有效率比较,差异具有统计学意义(P<0.05)。两组治疗后中医证候评分低于本组治疗前,且观察组治疗后低于对照组治疗后,差异具有统计学意义(P<0.05)。两组治疗后SAQ评分、SF-36评分均高于本组治疗前,且观察组治疗后高于对照组治疗后,差异具有统计学意义(P<0.05)。两组治疗后hs-CRP、Hcy、AIP低于本组治疗前,SOD高于本组治疗前;观察组治疗后hs-CRP、Hcy、AIP均低于对照组,SOD高于对照组,差异具有统计学意义(P<0.05)。结论:枳实薤白桂枝汤治疗稳定性冠心病痰阻心脉证,可有效缓解患者慢性炎症反应,抑制动脉粥样硬化进程,增强机体对氧化物的清除能力,提高患者生活质量。
文摘目的:观察桂姜枳实汤加味联合常规西药治疗冠状动脉粥样硬化性心脏病(简称冠心病)合并慢性心力衰竭的临床疗效。方法:将62例冠心病合并慢性心力衰竭患者按照随机数字表法分为对照组和观察组,每组各31例。对照组给予常规西药治疗,观察组在对照组治疗的基础上联合桂姜枳实汤加味治疗。比较两组患者的临床疗效及治疗前后中医证候评分、超声心动图指标[左室舒张末期内径(left ventricular end diastolic diameter,LVEDD)、左室收缩末期内径(Left ventricular end systolic diameter,LVESD)、左心室射血分数(left ventricular ejection fraction,LVEF)]、心率变异性指标、6分钟步行试验距离、明尼苏达心力衰竭生活质量问卷(minnesota living with heart failure questionnaire,MLHFQ)评分的变化情况。结果:观察组有效率为90.32%,对照组有效率为70.97%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后中医证候评分均低于本组治疗前,且观察组治疗后中医证候评分均低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后LVEDD、LVESD低于本组治疗前,LVEF高于本组治疗前,观察组治疗后LVEDD、LVESD低于对照组,LVEF高于对照组,差异均有统计学意义(P<0.05)。两组患者治疗后心率变异性水平均高于本组治疗前,且观察组治疗后心率变异性水平高于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后6分钟步行试验距离高于本组治疗前,MLHFFQ评分低于本组治疗前,观察组治疗后6分钟步行试验距离高于对照组,MLHFFQ评分低于对照组,差异具有统计学意义(P<0.05)。结论:桂姜枳实汤加味联合西药治疗冠心病合并慢性心力衰竭,可改善患者的临床症状、心功能及心率变异性水平。
