In order to select highly productive and enriched areas of high rank coalbed methane reservoirs,based on hydrologic geology as one of the main factors controlling coalbed methane(CBM) reservoir formations,the effect o...In order to select highly productive and enriched areas of high rank coalbed methane reservoirs,based on hydrologic geology as one of the main factors controlling coalbed methane(CBM) reservoir formations,the effect of hydrodynamic forces controlling CBM reservoir formations was studied by a physical simulation experiment in which we used CBM reservoir simulation facilities.The hydrodynamic conditions of high coal rank reservoirs in the Qinshui basin were analyzed.Our experiment shows the following results:under strong hydrodynamic alternating action,δC1 of coalbed methane reservoir changed from the start at -2.95%～-3.66%,and the lightening process occurred in phases;the CH4 volume reduced from 96.35% to 12.42%;the CO2 volume decreased from 0.75% in sample 1 to 0.68% in sample 2,then rose to 1.13% in sample 3;the N2 volume changed from 2.9% in sample 1 to 86.45% in sample 3.On one hand,these changes show the complexity of CBM reservoir formation;on the other hand,they indicate that strong hydrodynamic actions have an unfavorable impact on CBM reservoir formation.It was found that the gas volume and hydrodynamic intensity were negatively correlated and low hydrodynamic flow conditions might result in highly productive and enriched areas of high rank CBM.展开更多
Background Despite 100 years of research, the continued absence of well-established risk factors impedes the diagnosis and treatment of interstitial cystitis/painful bladder syndrome （IC/PBS）. We aimed to identify r...Background Despite 100 years of research, the continued absence of well-established risk factors impedes the diagnosis and treatment of interstitial cystitis/painful bladder syndrome （IC/PBS）. We aimed to identify risk factors in patients with lower urinary tract symptoms （LUTS） without urinary tract infection or benign prostate hyperplasia in China.Methods A total of 397 outpatients with LUTS presenting for care to urology clinics in several hospitals throughout China were surveyed using a standardized questionnaire and validated outcome measures. The definitions for painful bladder syndrome based on the O‘Leary-Sant interstitial cystitis symptom and problem indices were used. The prevalence of possible risk factors was analyzed using the Fisher＇s exact test and Pearson chi-square test, and multivariate predictive models were developed using binary Logistic regression methods.Results Of those multi-centre patients surveyed, including 174 women and 223 men, 41% （162/397） met criteria for painful bladder syndrome. There was a significant difference between women and men （55% （95/174） vs. 30% （67/223）,P 〈0.001）. Women with IC/PBS were more likely than those without IC/PBS to report a history of gynecological infections （odds ratio （OR）： 2.85; 95% confidence interval （CI）： 1.32-6.16, P=0.007）, intake of stimulatory foods （OR： 3.52; 95% CI：1.50-8.30; P=0.004）, irritable bowel （OR： 3.46; 95% CI： 1.22-9.80; P=0.014） and/or anorectal disease （OR： 2.68; 95% CI：1.12-6.40, P=0.023）. After adjusting for confounding factors, bladder pain was significantly associated with stimulatory foods （OR： 3.85; 95% CI： 1.58-9.36, P=0.003） and anorectal disease （OR： 2.76; 95% CI： 1.09-7.04, P=0.03） in women.Caffeine beverage intake （OR： 3.54; 95% CI： 1.54-8.12, P=0.003） was identified the only modifiable association noted in multivariate analysis of men.Conclusions We found that stimutatory foods, anorectal disease and caffeine beverages are potential risk factors for IC/PBS. Further studies are necessary to determine their role in the pathogenesis of this disorder.展开更多
Multiple endocrine neoplasia-2A （MEN 2A） is an autosomal dominant cancer syndrome characterized by medullary thyroid carcinoma, pheochromocytoma, and parathyroid hyperplasia. We report an unusual case of a patient w...Multiple endocrine neoplasia-2A （MEN 2A） is an autosomal dominant cancer syndrome characterized by medullary thyroid carcinoma, pheochromocytoma, and parathyroid hyperplasia. We report an unusual case of a patient who was associated with renal agenesis. Only two cases （a mother and her son） of one report were lbund in the literature.展开更多
基金Project 2002CB211705 supported by the National Basic Research Program of China
文摘In order to select highly productive and enriched areas of high rank coalbed methane reservoirs,based on hydrologic geology as one of the main factors controlling coalbed methane(CBM) reservoir formations,the effect of hydrodynamic forces controlling CBM reservoir formations was studied by a physical simulation experiment in which we used CBM reservoir simulation facilities.The hydrodynamic conditions of high coal rank reservoirs in the Qinshui basin were analyzed.Our experiment shows the following results:under strong hydrodynamic alternating action,δC1 of coalbed methane reservoir changed from the start at -2.95%～-3.66%,and the lightening process occurred in phases;the CH4 volume reduced from 96.35% to 12.42%;the CO2 volume decreased from 0.75% in sample 1 to 0.68% in sample 2,then rose to 1.13% in sample 3;the N2 volume changed from 2.9% in sample 1 to 86.45% in sample 3.On one hand,these changes show the complexity of CBM reservoir formation;on the other hand,they indicate that strong hydrodynamic actions have an unfavorable impact on CBM reservoir formation.It was found that the gas volume and hydrodynamic intensity were negatively correlated and low hydrodynamic flow conditions might result in highly productive and enriched areas of high rank CBM.
文摘Background Despite 100 years of research, the continued absence of well-established risk factors impedes the diagnosis and treatment of interstitial cystitis/painful bladder syndrome （IC/PBS）. We aimed to identify risk factors in patients with lower urinary tract symptoms （LUTS） without urinary tract infection or benign prostate hyperplasia in China.Methods A total of 397 outpatients with LUTS presenting for care to urology clinics in several hospitals throughout China were surveyed using a standardized questionnaire and validated outcome measures. The definitions for painful bladder syndrome based on the O‘Leary-Sant interstitial cystitis symptom and problem indices were used. The prevalence of possible risk factors was analyzed using the Fisher＇s exact test and Pearson chi-square test, and multivariate predictive models were developed using binary Logistic regression methods.Results Of those multi-centre patients surveyed, including 174 women and 223 men, 41% （162/397） met criteria for painful bladder syndrome. There was a significant difference between women and men （55% （95/174） vs. 30% （67/223）,P 〈0.001）. Women with IC/PBS were more likely than those without IC/PBS to report a history of gynecological infections （odds ratio （OR）： 2.85; 95% confidence interval （CI）： 1.32-6.16, P=0.007）, intake of stimulatory foods （OR： 3.52; 95% CI：1.50-8.30; P=0.004）, irritable bowel （OR： 3.46; 95% CI： 1.22-9.80; P=0.014） and/or anorectal disease （OR： 2.68; 95% CI：1.12-6.40, P=0.023）. After adjusting for confounding factors, bladder pain was significantly associated with stimulatory foods （OR： 3.85; 95% CI： 1.58-9.36, P=0.003） and anorectal disease （OR： 2.76; 95% CI： 1.09-7.04, P=0.03） in women.Caffeine beverage intake （OR： 3.54; 95% CI： 1.54-8.12, P=0.003） was identified the only modifiable association noted in multivariate analysis of men.Conclusions We found that stimutatory foods, anorectal disease and caffeine beverages are potential risk factors for IC/PBS. Further studies are necessary to determine their role in the pathogenesis of this disorder.
文摘Multiple endocrine neoplasia-2A （MEN 2A） is an autosomal dominant cancer syndrome characterized by medullary thyroid carcinoma, pheochromocytoma, and parathyroid hyperplasia. We report an unusual case of a patient who was associated with renal agenesis. Only two cases （a mother and her son） of one report were lbund in the literature.
