生态修复是提升生态环境质量,实现自然资源的可持续使用,解决环境污染、恢复自然生态平衡的过程,从提出“生态修复”这个概念至今,国内外学者及科研机构已有大量工作和研究成果。本研究基于Web of Science核心数据库和CNKI核心数据库,筛...生态修复是提升生态环境质量,实现自然资源的可持续使用,解决环境污染、恢复自然生态平衡的过程,从提出“生态修复”这个概念至今,国内外学者及科研机构已有大量工作和研究成果。本研究基于Web of Science核心数据库和CNKI核心数据库,筛选SCI论文216篇和中文核心231篇,使用CiteSpace软件进行分析,系统梳理生态修复的研究思路与方法、应用案例、存在问题及未来研究重点。主要结论如下:1)生态修复研究主题从最开始的单一生态系统逐渐转向多维度耦合,研究方法也从人工干预修复向近自然修复手段发展;2)针对不同生态系统类型均有各自的生态修复方法,缺点是修复方式单一、缺乏对整体生态系统效应的研究;3)生态修复主要存在缺乏对生态系统整体性的恢复措施,缺乏多维度、多类型、多方式组合的综合治理与修复方案、理论研究未与实践相结合等问题。未来研究重点应从整体性角度推进生态修复研究,开展多要素协同生态修复实践工程,发展更多区域与国家之间的合作,加强多对象、多尺度的生态修复。展开更多
The photocatalytic degradation of dye Rhodamine B （RhB） in the presence of TiO2 nanostdpe or P25 under visible light irradiation was investigated. The degradation intermediates were identified using Infrared spectra...The photocatalytic degradation of dye Rhodamine B （RhB） in the presence of TiO2 nanostdpe or P25 under visible light irradiation was investigated. The degradation intermediates were identified using Infrared spectra （IR spectra）, ^1H nuclear magnetic resonance （^1HNMR） spectra, and gas chromatography-mass spectroscopy （GC-MS）. The IR and the ^1HNMR results showed that the large conjugated chromophore structure of RhB was efficiently destroyed under visible light irradiation in both the photocatalytic systems （TiO2 nanostfipe or P25 and Rhodamine B systems）. GC-MS results showed that the main identified intermediates were ethanediotic acid, 1,2-benzenedicarboxylic acid, 4-hydroxy benzoic acid and benzoic acid, which were almost the same in the TiO2 nanostdpes and P25 systems. This work provides a good insight into the reaction pathway（s） for the TiO2-assisted photocatalytic degradation of dye pollutants under visible light irradiation.展开更多
OBJECTIVE The aim of the study was to characterize the pharmacokinetics(PK) and pharmacodynamics(PD) profile of cisatracurium in 0-2 years and 2-5 years old children patients with cheilopalatognathus,to find if there ...OBJECTIVE The aim of the study was to characterize the pharmacokinetics(PK) and pharmacodynamics(PD) profile of cisatracurium in 0-2 years and 2-5 years old children patients with cheilopalatognathus,to find if there are some connections between the different muscle relaxation action and different PK procedure.METHODS 14 children patients were divided into two groups,≤2 years and 2-5 years group,venous samples were taken before injection of a 0.15 mg·kg-1 dose of cisatracurium and then at 2,5,10,30,60,90,and 120 min.Cisatracurium plasma concentrations were determined by ultra-performance liquid chromatography/electrospray ionization/triple quadrupole tandem mass spectrometer system(UPLC/MS/MS).The degree of neuromuscular block was measured by train of four(TOF) testing.An indirect PK-PD link model with a sigmoid E max model was established using Win Nonlin software.The model were applied to PK and PD data analysis,respectively.RESULTS The TOF monitor parameters showed that cisatracurium works very quickly,the onset time were(2.64±0.93) min and(2.59 ± 0.90) min for ≤2 years and 2-5 years group respectively.Young children ≤2 years have longer muscle blocking duration time(62.5 ± 6.01 min vs 53.86 ± 12.18 min) and slower recovery index(32.14±7.10 min and 27.43±10.63 min) than those children in group of 2-5 years.More children ≤2 years have postoperative complication than that in 2-5 children.PK parameters showed that there were no statistical differences in blood concentration and pharmacokinetic parameters.While the concentration of cisatracurium in muscle site calculated by using PK/PD model were higher and longer for ≤2 year children than that of 2-5 year children.This means that cisatracurium could stay at high concentration for a longer time in younger children' muscle tissue.CONCLUSION As a result young children tend to have postoperative complications related to slower muscle recovery action and increased concentration in skeletal muscle.So more careful observation and monitor are needed for younger children,our study could be of use in clinical practice for the administration of cisatracurium to children patients.展开更多
文摘生态修复是提升生态环境质量,实现自然资源的可持续使用,解决环境污染、恢复自然生态平衡的过程,从提出“生态修复”这个概念至今,国内外学者及科研机构已有大量工作和研究成果。本研究基于Web of Science核心数据库和CNKI核心数据库,筛选SCI论文216篇和中文核心231篇,使用CiteSpace软件进行分析,系统梳理生态修复的研究思路与方法、应用案例、存在问题及未来研究重点。主要结论如下:1)生态修复研究主题从最开始的单一生态系统逐渐转向多维度耦合,研究方法也从人工干预修复向近自然修复手段发展;2)针对不同生态系统类型均有各自的生态修复方法,缺点是修复方式单一、缺乏对整体生态系统效应的研究;3)生态修复主要存在缺乏对生态系统整体性的恢复措施,缺乏多维度、多类型、多方式组合的综合治理与修复方案、理论研究未与实践相结合等问题。未来研究重点应从整体性角度推进生态修复研究,开展多要素协同生态修复实践工程,发展更多区域与国家之间的合作,加强多对象、多尺度的生态修复。
基金Project supported by the National Natural Science Foundation of China(No. 20567002)the Scientific Research Startup Foundation of InnerMongolia University (No. 203044)+2 种基金the Education Department of InnerMongolia Autonomous Region (No. NJ04093, NJ03121)the ChunhuiPlan of the Education Ministry (No. Z2004-2-15030)the "513 TalentsPlan" of Inner Mongolia University.
文摘The photocatalytic degradation of dye Rhodamine B （RhB） in the presence of TiO2 nanostdpe or P25 under visible light irradiation was investigated. The degradation intermediates were identified using Infrared spectra （IR spectra）, ^1H nuclear magnetic resonance （^1HNMR） spectra, and gas chromatography-mass spectroscopy （GC-MS）. The IR and the ^1HNMR results showed that the large conjugated chromophore structure of RhB was efficiently destroyed under visible light irradiation in both the photocatalytic systems （TiO2 nanostfipe or P25 and Rhodamine B systems）. GC-MS results showed that the main identified intermediates were ethanediotic acid, 1,2-benzenedicarboxylic acid, 4-hydroxy benzoic acid and benzoic acid, which were almost the same in the TiO2 nanostdpes and P25 systems. This work provides a good insight into the reaction pathway（s） for the TiO2-assisted photocatalytic degradation of dye pollutants under visible light irradiation.
基金supported by Top Young Innovative Talents of Beijing(CIT&TCD201404174)Basic Clinical Cooperation Project of Capital Medical University(14JL79)
文摘OBJECTIVE The aim of the study was to characterize the pharmacokinetics(PK) and pharmacodynamics(PD) profile of cisatracurium in 0-2 years and 2-5 years old children patients with cheilopalatognathus,to find if there are some connections between the different muscle relaxation action and different PK procedure.METHODS 14 children patients were divided into two groups,≤2 years and 2-5 years group,venous samples were taken before injection of a 0.15 mg·kg-1 dose of cisatracurium and then at 2,5,10,30,60,90,and 120 min.Cisatracurium plasma concentrations were determined by ultra-performance liquid chromatography/electrospray ionization/triple quadrupole tandem mass spectrometer system(UPLC/MS/MS).The degree of neuromuscular block was measured by train of four(TOF) testing.An indirect PK-PD link model with a sigmoid E max model was established using Win Nonlin software.The model were applied to PK and PD data analysis,respectively.RESULTS The TOF monitor parameters showed that cisatracurium works very quickly,the onset time were(2.64±0.93) min and(2.59 ± 0.90) min for ≤2 years and 2-5 years group respectively.Young children ≤2 years have longer muscle blocking duration time(62.5 ± 6.01 min vs 53.86 ± 12.18 min) and slower recovery index(32.14±7.10 min and 27.43±10.63 min) than those children in group of 2-5 years.More children ≤2 years have postoperative complication than that in 2-5 children.PK parameters showed that there were no statistical differences in blood concentration and pharmacokinetic parameters.While the concentration of cisatracurium in muscle site calculated by using PK/PD model were higher and longer for ≤2 year children than that of 2-5 year children.This means that cisatracurium could stay at high concentration for a longer time in younger children' muscle tissue.CONCLUSION As a result young children tend to have postoperative complications related to slower muscle recovery action and increased concentration in skeletal muscle.So more careful observation and monitor are needed for younger children,our study could be of use in clinical practice for the administration of cisatracurium to children patients.
