Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic ...Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic nucleus(STN),globus pallidus(GPi),meso-ventral thalamic nucleus(VIM),pontine peduncle nucleus(PPN),posterior subthalamic region(PSA)and zonation of undetermined zone(ZI).This paper summarizes the efficacy of each target in the treatment of PD with DBS,not only makes a systematic analysis and comparison of motor symptoms,but also makes a detailed description of the efficacy of non-motor symptoms,so as to provide a personalized treatment basis for PD patients to select appropriate target targets in DBS.展开更多
Based on the target of energy-saving and emission reduction(ESER)in the national five-year plan in China,an extended directional distance function model(E-DDF)including undesirable input and undesirable output is prop...Based on the target of energy-saving and emission reduction(ESER)in the national five-year plan in China,an extended directional distance function model(E-DDF)including undesirable input and undesirable output is proposed,and energy-saving efficiency,emission reduction efficiency,ESER efficiency are defined.Then the weighted directional distance function model is constructed for the total factors efficiency index model of ESER to reflect its dynamic change.The results show that the ESER efficiency continues to rise during the three five-year plan periods(2006-2017),and the efficiency score of the east area are higher than those of central and west area.The disparity and change of energy-saving efficiency among difference regions are not obvious,but the disparity and change of emission reduction efficiency are the main reasons for the improvement and change of ESER efficiency index.In the long run,the ESER efficiency is in a dynamic upward trend,and the effect of technological progress is more obvious compared with technical efficient index.展开更多
基金Natural Science Foundation of Hainan Province (No.821RC682)。
文摘Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic nucleus(STN),globus pallidus(GPi),meso-ventral thalamic nucleus(VIM),pontine peduncle nucleus(PPN),posterior subthalamic region(PSA)and zonation of undetermined zone(ZI).This paper summarizes the efficacy of each target in the treatment of PD with DBS,not only makes a systematic analysis and comparison of motor symptoms,but also makes a detailed description of the efficacy of non-motor symptoms,so as to provide a personalized treatment basis for PD patients to select appropriate target targets in DBS.
基金supported by the National Social Science Fund of China(Grant No.18BTJ003).
文摘Based on the target of energy-saving and emission reduction(ESER)in the national five-year plan in China,an extended directional distance function model(E-DDF)including undesirable input and undesirable output is proposed,and energy-saving efficiency,emission reduction efficiency,ESER efficiency are defined.Then the weighted directional distance function model is constructed for the total factors efficiency index model of ESER to reflect its dynamic change.The results show that the ESER efficiency continues to rise during the three five-year plan periods(2006-2017),and the efficiency score of the east area are higher than those of central and west area.The disparity and change of energy-saving efficiency among difference regions are not obvious,but the disparity and change of emission reduction efficiency are the main reasons for the improvement and change of ESER efficiency index.In the long run,the ESER efficiency is in a dynamic upward trend,and the effect of technological progress is more obvious compared with technical efficient index.