In the study, an improved approach was proposed to identify the contribution shares of three group factors that are climate, technology and input, social economic factors by which the grain production is shaped. In or...In the study, an improved approach was proposed to identify the contribution shares of three group factors that are climate, technology and input, social economic factors by which the grain production is shaped. In order to calibrate the method, Jiangxi Province, one of the main paddy rice producers in China was taken as an example. Based on 50 years （1961-2010） meteorological and statistic data, using GIS and statistical analysis tools, the three group factors that in certain extent impact China＇s paddy rice production have been analyzed quantitatively. The individual and interactive contribution shares of each factor group have been identiifed via eta square （η2）. In the paper, two group ordinary leasr square （OLS） models, paddy models and climate models, have been constructed for further analysis. Each model group consists of seven models, one full model and six partial models. The results of paddy models show that climate factors individually and interactively contribute 11.42-15.25%explanatory power to the variation of paddy rice production in the studied province. Technology and input factors contribute 16.17%individually and another 8.46%interactively together with climate factors, totally contributing about 25%. Social economic factors contribute about 7%of which 4.65%is individual contribution and 2.49%is interactive contribution together with climate factors. The three factor groups individually contribute about 23%and interactively contribute additional 41%to paddy rice production. In addition every two of the three factor groups also function interactively and contribute about 22%. Among the three factor groups, technology and input are the most important factors to paddy rice production. The results of climate models support the results of paddy models, and display that solar radiation （indicated by sunshine hour variable） is the dominate climate factor for paddy rice production.展开更多
探究不同施磷量对胡麻籽粒蛋白质和金属元素含量的影响,为构建磷肥高效管理提供依据。通过2018和2019年连续2年大田试验,设置5个施磷水平(0、40、80、120、160 kg P_(2)O_(5)·hm^(-2)),3个品种(陇亚杂1号、陇亚14号和张亚2号)两因...探究不同施磷量对胡麻籽粒蛋白质和金属元素含量的影响,为构建磷肥高效管理提供依据。通过2018和2019年连续2年大田试验,设置5个施磷水平(0、40、80、120、160 kg P_(2)O_(5)·hm^(-2)),3个品种(陇亚杂1号、陇亚14号和张亚2号)两因素随机区组试验,研究不同磷水平对胡麻籽粒产量,籽粒蛋白质、钾、钙、钠、镁含量的作用效果。结果表明,随施磷量增加,胡麻籽粒产量、籽粒钾、钙、镁含量不同程度增加;相比不施磷,施磷处理籽粒产量、籽粒钾、钙、镁含量,分别平均提高17.6%、11.6%、17.6%和12.5%;籽粒蛋白质和钠含量不受磷影响。综合考虑胡麻籽粒产量、籽粒钾、钙、镁含量和生态环境,该区域施磷80 kg P_(2)O_(5)·hm^(-2)较佳,可协同增加胡麻籽粒产量及籽粒钙、镁含量;降低环境风险,减少碳排放。展开更多
目的通过蛋白组学技术探讨宫颈癌癌组织中的差异表达蛋白。方法纳入于新乡市中心医院就诊的12例宫颈癌患者和12例宫颈活检结果正常者作为研究对象。将24例研究对象分为实验组和验证组,其中10例宫颈癌患者和10例宫颈活检正常者构成实验组...目的通过蛋白组学技术探讨宫颈癌癌组织中的差异表达蛋白。方法纳入于新乡市中心医院就诊的12例宫颈癌患者和12例宫颈活检结果正常者作为研究对象。将24例研究对象分为实验组和验证组,其中10例宫颈癌患者和10例宫颈活检正常者构成实验组,其余2例宫颈癌患者和2例宫颈活检正常者构成验证组。通过蛋白组学技术探讨宫颈癌患者(n=10例)癌组织与正常宫颈组织(n=10例)中的差异表达蛋白,并将差异表达蛋白进行GO富集和KEGG富集分析,通过蛋白互作(protein protein interaction,PPI)分析筛选出与宫颈癌发病机制相关的关键蛋白,选取5种相关度最为显著的蛋白在验证组中进行Western blot验证。结果共有4718个蛋白被定量分析,相对于正常宫颈组织,宫颈癌癌组织中显著上调的蛋白有190个,显著下调的蛋白有163个。对发生显著改变的353个蛋白进行GO富集分析和KEGG富集分析,结果显示,差异蛋白涉及的生物学过程主要为中性粒细胞活化、氧化应激、免疫应答及急性相反应等,差异蛋白主要涉及IL-17信号通路、人乳头瘤病毒感染相关通路、PI3K-AKT信号通路、氧化磷酸化、MAPK信号通路等。PPI分析筛选出109个差异蛋白,主要涉及到免疫炎症、氧化应激、IL-17信号通路等。IKKβ、CDK2、COX4、AKT和Ras蛋白是PPI结果中相关度最为显著的前5种蛋白,Western blot结果显示,宫颈癌癌组织中IKKβ、CDK2、COX4、p-AKT和Ras蛋白表达水平显著升高,差异均具有统计学意义(P<0.05)。结论蛋白组学技术筛选出可能参与宫颈癌发生发展的相关蛋白及免疫学信号通路,为宫颈癌的发病机制和治疗靶点进一步提供了方向。展开更多
In order to evaluate the imaging quality of CCD cameras fully and rapidly,the minimum resolvable contrast (MRC) is presented in this paper and the system of measuring MRC is constructed as well,in which two integratin...In order to evaluate the imaging quality of CCD cameras fully and rapidly,the minimum resolvable contrast (MRC) is presented in this paper and the system of measuring MRC is constructed as well,in which two integrating spheres are proposed to illuminate two sides of the target respectively.The variable contrast can be obtained by regulating the luminance of integrating spheres. Experimental results indicate that the error of measuring luminance is within ±0.3 cd/m-2,MRC rises with the increase of the spatial frequency.The experimental results show that the method proposed is an effective approach to evaluate the imaging quality of CCD cameras.展开更多
目的:观察加味清脑方治疗气滞血瘀型卒中后抑郁的临床疗效。方法:将76例气滞血瘀型卒中后抑郁患者按照随机数字表法分为对照组和治疗组,每组各38例。两组均给予原发病治疗,对照组给予氟哌噻吨美利曲辛片治疗,治疗组在对照组治疗的基础...目的:观察加味清脑方治疗气滞血瘀型卒中后抑郁的临床疗效。方法:将76例气滞血瘀型卒中后抑郁患者按照随机数字表法分为对照组和治疗组,每组各38例。两组均给予原发病治疗,对照组给予氟哌噻吨美利曲辛片治疗,治疗组在对照组治疗的基础上口服加味清脑方。比较两组患者的临床疗效及治疗前后汉密尔顿焦虑量表(hamilton depression scale,HAMD)评分、美国国立卫生院神经功能缺损评分(national institutes of health neurological deficit score,NIHSS)、Barthel指数量表(barthel index,BI)评分变化情况。结果:两组患者治疗后HAMD评分低于本组治疗前,且治疗后治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后NIHSS评分低于本组治疗前,且治疗后治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后BI评分高于本组治疗前,且治疗后治疗组高于对照组,差异具有统计学意义(P<0.05)。对照组有效率为26.31%,治疗组有效率为68.42%,两组患者有效率比较,差异具有统计学意义(P<0.05)。结论:加味清脑方治疗气滞血瘀型卒中后抑郁,可改善患者抑郁状态及神经功能缺损情况,提高患者的日常生活能力。展开更多
基金financed by the National Basic Research Program of China(2010CB951502)
文摘In the study, an improved approach was proposed to identify the contribution shares of three group factors that are climate, technology and input, social economic factors by which the grain production is shaped. In order to calibrate the method, Jiangxi Province, one of the main paddy rice producers in China was taken as an example. Based on 50 years （1961-2010） meteorological and statistic data, using GIS and statistical analysis tools, the three group factors that in certain extent impact China＇s paddy rice production have been analyzed quantitatively. The individual and interactive contribution shares of each factor group have been identiifed via eta square （η2）. In the paper, two group ordinary leasr square （OLS） models, paddy models and climate models, have been constructed for further analysis. Each model group consists of seven models, one full model and six partial models. The results of paddy models show that climate factors individually and interactively contribute 11.42-15.25%explanatory power to the variation of paddy rice production in the studied province. Technology and input factors contribute 16.17%individually and another 8.46%interactively together with climate factors, totally contributing about 25%. Social economic factors contribute about 7%of which 4.65%is individual contribution and 2.49%is interactive contribution together with climate factors. The three factor groups individually contribute about 23%and interactively contribute additional 41%to paddy rice production. In addition every two of the three factor groups also function interactively and contribute about 22%. Among the three factor groups, technology and input are the most important factors to paddy rice production. The results of climate models support the results of paddy models, and display that solar radiation （indicated by sunshine hour variable） is the dominate climate factor for paddy rice production.
文摘探究不同施磷量对胡麻籽粒蛋白质和金属元素含量的影响,为构建磷肥高效管理提供依据。通过2018和2019年连续2年大田试验,设置5个施磷水平(0、40、80、120、160 kg P_(2)O_(5)·hm^(-2)),3个品种(陇亚杂1号、陇亚14号和张亚2号)两因素随机区组试验,研究不同磷水平对胡麻籽粒产量,籽粒蛋白质、钾、钙、钠、镁含量的作用效果。结果表明,随施磷量增加,胡麻籽粒产量、籽粒钾、钙、镁含量不同程度增加;相比不施磷,施磷处理籽粒产量、籽粒钾、钙、镁含量,分别平均提高17.6%、11.6%、17.6%和12.5%;籽粒蛋白质和钠含量不受磷影响。综合考虑胡麻籽粒产量、籽粒钾、钙、镁含量和生态环境,该区域施磷80 kg P_(2)O_(5)·hm^(-2)较佳,可协同增加胡麻籽粒产量及籽粒钙、镁含量;降低环境风险,减少碳排放。
文摘目的通过蛋白组学技术探讨宫颈癌癌组织中的差异表达蛋白。方法纳入于新乡市中心医院就诊的12例宫颈癌患者和12例宫颈活检结果正常者作为研究对象。将24例研究对象分为实验组和验证组,其中10例宫颈癌患者和10例宫颈活检正常者构成实验组,其余2例宫颈癌患者和2例宫颈活检正常者构成验证组。通过蛋白组学技术探讨宫颈癌患者(n=10例)癌组织与正常宫颈组织(n=10例)中的差异表达蛋白,并将差异表达蛋白进行GO富集和KEGG富集分析,通过蛋白互作(protein protein interaction,PPI)分析筛选出与宫颈癌发病机制相关的关键蛋白,选取5种相关度最为显著的蛋白在验证组中进行Western blot验证。结果共有4718个蛋白被定量分析,相对于正常宫颈组织,宫颈癌癌组织中显著上调的蛋白有190个,显著下调的蛋白有163个。对发生显著改变的353个蛋白进行GO富集分析和KEGG富集分析,结果显示,差异蛋白涉及的生物学过程主要为中性粒细胞活化、氧化应激、免疫应答及急性相反应等,差异蛋白主要涉及IL-17信号通路、人乳头瘤病毒感染相关通路、PI3K-AKT信号通路、氧化磷酸化、MAPK信号通路等。PPI分析筛选出109个差异蛋白,主要涉及到免疫炎症、氧化应激、IL-17信号通路等。IKKβ、CDK2、COX4、AKT和Ras蛋白是PPI结果中相关度最为显著的前5种蛋白,Western blot结果显示,宫颈癌癌组织中IKKβ、CDK2、COX4、p-AKT和Ras蛋白表达水平显著升高,差异均具有统计学意义(P<0.05)。结论蛋白组学技术筛选出可能参与宫颈癌发生发展的相关蛋白及免疫学信号通路,为宫颈癌的发病机制和治疗靶点进一步提供了方向。
基金Supported by Science and Technology Research Project of Educa-tion Department of Heilongjiang Province(10051065)
文摘In order to evaluate the imaging quality of CCD cameras fully and rapidly,the minimum resolvable contrast (MRC) is presented in this paper and the system of measuring MRC is constructed as well,in which two integrating spheres are proposed to illuminate two sides of the target respectively.The variable contrast can be obtained by regulating the luminance of integrating spheres. Experimental results indicate that the error of measuring luminance is within ±0.3 cd/m-2,MRC rises with the increase of the spatial frequency.The experimental results show that the method proposed is an effective approach to evaluate the imaging quality of CCD cameras.
文摘目的:观察加味清脑方治疗气滞血瘀型卒中后抑郁的临床疗效。方法:将76例气滞血瘀型卒中后抑郁患者按照随机数字表法分为对照组和治疗组,每组各38例。两组均给予原发病治疗,对照组给予氟哌噻吨美利曲辛片治疗,治疗组在对照组治疗的基础上口服加味清脑方。比较两组患者的临床疗效及治疗前后汉密尔顿焦虑量表(hamilton depression scale,HAMD)评分、美国国立卫生院神经功能缺损评分(national institutes of health neurological deficit score,NIHSS)、Barthel指数量表(barthel index,BI)评分变化情况。结果:两组患者治疗后HAMD评分低于本组治疗前,且治疗后治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后NIHSS评分低于本组治疗前,且治疗后治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后BI评分高于本组治疗前,且治疗后治疗组高于对照组,差异具有统计学意义(P<0.05)。对照组有效率为26.31%,治疗组有效率为68.42%,两组患者有效率比较,差异具有统计学意义(P<0.05)。结论:加味清脑方治疗气滞血瘀型卒中后抑郁,可改善患者抑郁状态及神经功能缺损情况,提高患者的日常生活能力。
