目的:探讨尿常规与尿微量白蛋白检测在糖尿病早期肾损伤中的诊断价值。方法:收治糖尿病患者86例为观察组,另选取同期健康体检者80例为对照组。两组分别行尿常规、尿微量白蛋白(mALB)检测;再根据尿常规中尿蛋白定性结果进行分组,对比mAL...目的:探讨尿常规与尿微量白蛋白检测在糖尿病早期肾损伤中的诊断价值。方法:收治糖尿病患者86例为观察组,另选取同期健康体检者80例为对照组。两组分别行尿常规、尿微量白蛋白(mALB)检测;再根据尿常规中尿蛋白定性结果进行分组,对比mALB水平。结果:观察组尿常规检测显示阳性34例,阴性52例,阳性率39.53%;mALB检测显示阳性62例,阴性24例,阳性率72.09%。两组对比,差异有统计学意义(P<0.05);观察组24 h mALB水平高于对照组(P<0.05)。结论:尿常规检测难以发现糖尿病患者的早期肾损伤,而尿微量白蛋白是糖尿病早期肾损伤的重要标志。临床中应联合尿常规检测及mALB检测,从而有效诊断糖尿病病情及肾损伤。展开更多
Aself-accelerating three-component reaction was developed using the secondary amines,CS_(2),and sym-dibenzo-1,5-cyclooctadiene-3,7-diyne(DIBOD)as reactants.In this three-component reaction,the secondary amine reacts w...Aself-accelerating three-component reaction was developed using the secondary amines,CS_(2),and sym-dibenzo-1,5-cyclooctadiene-3,7-diyne(DIBOD)as reactants.In this three-component reaction,the secondary amine reacts with CS_(2) to form dithiocarbamate anion,which subsequently in-situ reacts with DIBOD behaving a self-accelerating reaction property.Specifically,the reaction of dithiocarbamate anion with the first alkyne of DIBOD activates the unreacted alkyne,which reacts with dithiocarbamate anion much faster than the original alkyne of DIBOD.Using the self-accelerating three-component reaction as polymerization reaction,a stoichiometric imbalance-promoted step-growth polymerization method was developed using the difunctional secondary amines,CS_(2),and DIBOD as monomer groups.This novel three-component polymerization can quickly produce high molecular weight dithiocarbamate-containing polymers under mild conditions using a slight molar excess of DIBOD to difunctional secondary amine monomer.Containing sulfur elements in the backbones,the resultant polymers hold high refractivity and may find potential applications in optical and optoelectronic fields.展开更多
文摘目的:探讨尿常规与尿微量白蛋白检测在糖尿病早期肾损伤中的诊断价值。方法:收治糖尿病患者86例为观察组,另选取同期健康体检者80例为对照组。两组分别行尿常规、尿微量白蛋白(mALB)检测;再根据尿常规中尿蛋白定性结果进行分组,对比mALB水平。结果:观察组尿常规检测显示阳性34例,阴性52例,阳性率39.53%;mALB检测显示阳性62例,阴性24例,阳性率72.09%。两组对比,差异有统计学意义(P<0.05);观察组24 h mALB水平高于对照组(P<0.05)。结论:尿常规检测难以发现糖尿病患者的早期肾损伤,而尿微量白蛋白是糖尿病早期肾损伤的重要标志。临床中应联合尿常规检测及mALB检测,从而有效诊断糖尿病病情及肾损伤。
基金This work was supported by the National Key Research and Development Program of China(No.2019YFA0210400)the National Natural Science Foundation of China(No.22071255).
文摘Aself-accelerating three-component reaction was developed using the secondary amines,CS_(2),and sym-dibenzo-1,5-cyclooctadiene-3,7-diyne(DIBOD)as reactants.In this three-component reaction,the secondary amine reacts with CS_(2) to form dithiocarbamate anion,which subsequently in-situ reacts with DIBOD behaving a self-accelerating reaction property.Specifically,the reaction of dithiocarbamate anion with the first alkyne of DIBOD activates the unreacted alkyne,which reacts with dithiocarbamate anion much faster than the original alkyne of DIBOD.Using the self-accelerating three-component reaction as polymerization reaction,a stoichiometric imbalance-promoted step-growth polymerization method was developed using the difunctional secondary amines,CS_(2),and DIBOD as monomer groups.This novel three-component polymerization can quickly produce high molecular weight dithiocarbamate-containing polymers under mild conditions using a slight molar excess of DIBOD to difunctional secondary amine monomer.Containing sulfur elements in the backbones,the resultant polymers hold high refractivity and may find potential applications in optical and optoelectronic fields.
