OBJECTIVE:To investigate the effectiveness and safety of Jiawei Xiaoyao pill(加味逍遥丸,JXP)in the treatment of symptoms associated with premenstrual syndrome(PMS).METHODS:A total of 144 regularly menstruating women w...OBJECTIVE:To investigate the effectiveness and safety of Jiawei Xiaoyao pill(加味逍遥丸,JXP)in the treatment of symptoms associated with premenstrual syndrome(PMS).METHODS:A total of 144 regularly menstruating women with PMS were recruited at 8 sites in China from August 2017 to December 2018,and randomized to receive either a JXP or a matching placebo(12 g/d,6 g twice a day)for 3 menstrual cycles.The primary indicator was the reduced Daily Record of Severity of Problems(DRSP)scores in the luteal phase after 3 months of treatment.The safety outcomes included clinical adverse events(AEs),adverse reactions(ARs),changes in vital signs,and laboratory tests.RESULTS:JXP surpassed the placebo in reducing DRSP scores(psychological/somatic dysfunction)in the luteal phase over 3 menstrual cycles of treatment(PFAS=0.002,PPPS=0.001).Additionally,there were no significant differences in the incidence of AEs,severe AEs,withdrawal due to AEs and ARs between the two groups(all P>0.05),and no clinically significant adverse medical events related to the test drug observed.CONCLUSIONS:JXP was superior to the placebo in relieving the symptoms associated with PMS,which signified that JXP may be effective,safe,and welltolerated as an alternative therapy.展开更多
大规模风电场并网对电力系统的安全稳定运行造成了较大影响,改善含风电场电力系统的小干扰稳定性日益重要。针对多机电力系统,提出一种联合双馈风机(doubly-fed induction generator, DFIG)与超导储能(superconducting magnetic energy ...大规模风电场并网对电力系统的安全稳定运行造成了较大影响,改善含风电场电力系统的小干扰稳定性日益重要。针对多机电力系统,提出一种联合双馈风机(doubly-fed induction generator, DFIG)与超导储能(superconducting magnetic energy storage,SMES)协调控制改善电力系统小干扰稳定性的方法。从风电场在电网的实际接入位置出发,通过对含风电场电力系统的节点电压方程进行修正和收缩处理,推导出同步机电磁功率改变量与DFIG接入的关联关系。在此基础上,依据互补群惯量加权平均角度相对值变换法则分析了风电场并网点的功率特性对系统振荡模式的阻尼影响,给出了提高系统小干扰稳定性的DFIG-SMES功率补偿协调控制策略。仿真结果表明,在系统小扰动动态过程中通过对SMES合理调节交换功率,增强了风电场并网点对系统的正阻尼作用,达到了提升系统小干扰稳定性的效果。展开更多
文摘OBJECTIVE:To investigate the effectiveness and safety of Jiawei Xiaoyao pill(加味逍遥丸,JXP)in the treatment of symptoms associated with premenstrual syndrome(PMS).METHODS:A total of 144 regularly menstruating women with PMS were recruited at 8 sites in China from August 2017 to December 2018,and randomized to receive either a JXP or a matching placebo(12 g/d,6 g twice a day)for 3 menstrual cycles.The primary indicator was the reduced Daily Record of Severity of Problems(DRSP)scores in the luteal phase after 3 months of treatment.The safety outcomes included clinical adverse events(AEs),adverse reactions(ARs),changes in vital signs,and laboratory tests.RESULTS:JXP surpassed the placebo in reducing DRSP scores(psychological/somatic dysfunction)in the luteal phase over 3 menstrual cycles of treatment(PFAS=0.002,PPPS=0.001).Additionally,there were no significant differences in the incidence of AEs,severe AEs,withdrawal due to AEs and ARs between the two groups(all P>0.05),and no clinically significant adverse medical events related to the test drug observed.CONCLUSIONS:JXP was superior to the placebo in relieving the symptoms associated with PMS,which signified that JXP may be effective,safe,and welltolerated as an alternative therapy.
文摘大规模风电场并网对电力系统的安全稳定运行造成了较大影响,改善含风电场电力系统的小干扰稳定性日益重要。针对多机电力系统,提出一种联合双馈风机(doubly-fed induction generator, DFIG)与超导储能(superconducting magnetic energy storage,SMES)协调控制改善电力系统小干扰稳定性的方法。从风电场在电网的实际接入位置出发,通过对含风电场电力系统的节点电压方程进行修正和收缩处理,推导出同步机电磁功率改变量与DFIG接入的关联关系。在此基础上,依据互补群惯量加权平均角度相对值变换法则分析了风电场并网点的功率特性对系统振荡模式的阻尼影响,给出了提高系统小干扰稳定性的DFIG-SMES功率补偿协调控制策略。仿真结果表明,在系统小扰动动态过程中通过对SMES合理调节交换功率,增强了风电场并网点对系统的正阻尼作用,达到了提升系统小干扰稳定性的效果。