Burden of Outpatient Visits Attributable to Ambient Temperature in Qingdao,China

Climate change has been referred to as one of the greatest threats to human health,with reports citing likely increases in extreme meteorological events.In this study,we estimated the relationships between temperature and outpatients at a major hospital in Qingdao,China,during 2015–2017,and assessed the morbidity burden.The results showed that both low and high temperatures were associated with an increased risk of outpatient visits.

HIV阳性的男男性行为者肛门人乳头瘤病毒感染现状分析

目的了解人免疫缺陷病毒(HIV)阳性的男男性行为者(MSM)肛门人乳头瘤病毒(HPV)感染情况。方法选择门诊患有尖锐湿疣或疑似尖锐湿疣的HIV阳性的MSM病例作为研究对象,共140例。采用基因芯片技术对肛门部位进行HPV检测。结果140例HIV阳性的MSM中,HPV感染率为77.86%(109/140),高危型HPV感染率为57.86%(81/140),低危型HPV感染率为61.43%(86/140)。低危型以HPV6和HPV11型检出率最高。高危型检出率前5位依次为:HPV16、58、51、52、18型。109例HIV阳性MSM感染了HPV的患者中,以多重感染为主,占71.56%(78/109),最多有十重感染。在HIV阳性的MSM中,≤20岁和>50岁年龄组HPV阳性率均为100%,21~30岁年龄组HPV阳性率为76.25%,31~40岁年龄组HPV阳性率为74.36%,41~50岁年龄组HPV阳性率为81.82%。CD4+T<500/μL和CD4+T≥500/μL组在HPV阳性率、低危型HPV感染率、多重基因型感染率差异均无统计学意义(χ2=1.46、3.40、1.53,P均>0.05),而两组在高危型HPV的感染率差异有统计学意义(χ2=4.50,P<0.05)。结论在HIV阳性的MSM中,HPV感染率和高危型HPV感染率均高,以多重感染为主,在各年龄组的阳性率都保持在较高水平,并未随年龄增长而降低,需要高度重视这一高危人群的HPV感染情况,从多方面做好HPV相关性恶性肿瘤的预防。