原发性脾淋巴瘤(primary splenic lymphoma,PSL)是一种极为罕见的疾病,在所有非霍奇金淋巴瘤(non-Hodgkin’s lymphoma,NHL)中占比<1%[1]。弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma,DLBCL)是PSL和NHL最常见的组织学亚型,其...原发性脾淋巴瘤(primary splenic lymphoma,PSL)是一种极为罕见的疾病,在所有非霍奇金淋巴瘤(non-Hodgkin’s lymphoma,NHL)中占比<1%[1]。弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma,DLBCL)是PSL和NHL最常见的组织学亚型,其他亚型包括脾绒毛性淋巴瘤、脾边缘区淋巴瘤和滤泡性淋巴瘤[2]。PSL的临床症状无特异性,极易造成误诊。现将曲靖市第一人民医院肝胆胰外科收治的一例PSL误诊为脾脓肿病例诊治经过报道如下,以期提高对PSL的临床认识。展开更多
Saline lakes represent a particularly interesting aquatic environment for harboring high microbial diversity.However,the microbial diversity in different states and locations of saline lake is often overlooked.We stud...Saline lakes represent a particularly interesting aquatic environment for harboring high microbial diversity.However,the microbial diversity in different states and locations of saline lake is often overlooked.We studied for the first time the diversity and relative composition of the microbial communities in the Chagan Lake,NE China,and investigated the dif ferences in microbial species and physical and chemical factors in different geographical localities of the lake.After extracting the total DNA of the sample,we tested the library with the established library,sequenced the qualified library with Illumina HiSeq 2500,and studied the bacterial diversity by 16 S rRNA targeted metagenomics analysis.Results reveal that the highest microbial abundance in Chagan Lake at genus level was Proteobacterium followed by Actinomycetes and Bacteroides.In addition,we compared the microbial composition within the lake using alpha-and beta-diversity indices,showing that both diversity and evenness were the highest in the middle of the lake and lowest in the west of lake areas,and in the upper,middle,and lower depth of water columns,the low water column had the highest species number in the whole water environment,but the dif ference was not significant.We believe that physicochemical factors contribute to the formation of microbial community composition and diversity.In aquaculture industry,it is impossible apply horticulture for making full use of the spatial dif ferences in the microbial composition of the water.Therefore,combining cultured aquatic animal with the most suitable microbial species is a good way to boost the breeding ef fect for greater economic value.展开更多
目的系统评价抗阻运动对冠心病患者心脏康复的干预效果。方法采用计算机检索引擎检索Pubmed、Cochrane、Web of science、Ovid、万方、知网、中国生物医学数据库,关于抗阻运动对冠心病患者心脏康复的相关研究,检索时间自建库至2018年9...目的系统评价抗阻运动对冠心病患者心脏康复的干预效果。方法采用计算机检索引擎检索Pubmed、Cochrane、Web of science、Ovid、万方、知网、中国生物医学数据库,关于抗阻运动对冠心病患者心脏康复的相关研究,检索时间自建库至2018年9月。由2位研究者独立按照纳入与排除标准筛选文献,提取资料和评价纳入研究的方法学质量,采用Rev Man 5.3软件进行Meta分析。结果最终纳入7篇随机对照研究,2篇类实验研究,共693例患者,Meta分析结果显示:抗阻运动可以更明显提高峰值摄氧量(VO2Peak),6 min步行试验距离(SMWT),改善患者的心肺功能和活动能力。抗阻运动适用于稳定型冠心病患者或冠心病术后的患者,建议在具有资质的专业人员的指导下进行训练。结论抗阻运动或抗阻运动联合有氧运动较其他运动方式在冠心病患者的康复治疗上具有更好的效果。展开更多
文摘原发性脾淋巴瘤(primary splenic lymphoma,PSL)是一种极为罕见的疾病,在所有非霍奇金淋巴瘤(non-Hodgkin’s lymphoma,NHL)中占比<1%[1]。弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma,DLBCL)是PSL和NHL最常见的组织学亚型,其他亚型包括脾绒毛性淋巴瘤、脾边缘区淋巴瘤和滤泡性淋巴瘤[2]。PSL的临床症状无特异性,极易造成误诊。现将曲靖市第一人民医院肝胆胰外科收治的一例PSL误诊为脾脓肿病例诊治经过报道如下,以期提高对PSL的临床认识。
基金Supported by the National Natural Sciences Foundational of China(No.30972191)the 948 Program from the Ministry of Agriculture of China(No.2014Z34)
文摘Saline lakes represent a particularly interesting aquatic environment for harboring high microbial diversity.However,the microbial diversity in different states and locations of saline lake is often overlooked.We studied for the first time the diversity and relative composition of the microbial communities in the Chagan Lake,NE China,and investigated the dif ferences in microbial species and physical and chemical factors in different geographical localities of the lake.After extracting the total DNA of the sample,we tested the library with the established library,sequenced the qualified library with Illumina HiSeq 2500,and studied the bacterial diversity by 16 S rRNA targeted metagenomics analysis.Results reveal that the highest microbial abundance in Chagan Lake at genus level was Proteobacterium followed by Actinomycetes and Bacteroides.In addition,we compared the microbial composition within the lake using alpha-and beta-diversity indices,showing that both diversity and evenness were the highest in the middle of the lake and lowest in the west of lake areas,and in the upper,middle,and lower depth of water columns,the low water column had the highest species number in the whole water environment,but the dif ference was not significant.We believe that physicochemical factors contribute to the formation of microbial community composition and diversity.In aquaculture industry,it is impossible apply horticulture for making full use of the spatial dif ferences in the microbial composition of the water.Therefore,combining cultured aquatic animal with the most suitable microbial species is a good way to boost the breeding ef fect for greater economic value.
文摘目的系统评价抗阻运动对冠心病患者心脏康复的干预效果。方法采用计算机检索引擎检索Pubmed、Cochrane、Web of science、Ovid、万方、知网、中国生物医学数据库,关于抗阻运动对冠心病患者心脏康复的相关研究,检索时间自建库至2018年9月。由2位研究者独立按照纳入与排除标准筛选文献,提取资料和评价纳入研究的方法学质量,采用Rev Man 5.3软件进行Meta分析。结果最终纳入7篇随机对照研究,2篇类实验研究,共693例患者,Meta分析结果显示:抗阻运动可以更明显提高峰值摄氧量(VO2Peak),6 min步行试验距离(SMWT),改善患者的心肺功能和活动能力。抗阻运动适用于稳定型冠心病患者或冠心病术后的患者,建议在具有资质的专业人员的指导下进行训练。结论抗阻运动或抗阻运动联合有氧运动较其他运动方式在冠心病患者的康复治疗上具有更好的效果。
