Experimental investigations were conducted on the adsorption characteristics of 2,6-dichlorophenol by two hypercrosslinked resins ZH-01 and XAD-4. The static adsorption was studied. Within temperature range of 288K-31...Experimental investigations were conducted on the adsorption characteristics of 2,6-dichlorophenol by two hypercrosslinked resins ZH-01 and XAD-4. The static adsorption was studied. Within temperature range of 288K-313K, the equilibrium adsorption date was fitted to freundlich adsorption isotherm models to evaluate the model parameters. The enthalpies, free energy, entropy were indicative of an exothermic, a spontaneous and disorder decreasing process. The magnitudes for 2,6-dichlorophenol on ZH-01 showed a chemisorption＇s transitions while on XAD-4 shows a physical adsorption process. The results showed that the ZH-01 adsorbents were better than the Amberlite XAD-4 for removing the 2,6-dichlorophenol in aqueous solutions.展开更多
目的搭建器官移植受者全生命周期数字化健康管理系统(the system for the whole life-cycle management of organ transplant recipient,SWOR),总结试用SWOR经验。方法利用智能手机应用程序(application,APP)和微信小程序,搭建包括诊疗...目的搭建器官移植受者全生命周期数字化健康管理系统(the system for the whole life-cycle management of organ transplant recipient,SWOR),总结试用SWOR经验。方法利用智能手机应用程序(application,APP)和微信小程序,搭建包括诊疗过程、日常指标、检查结果、影像报告、用药方案和医患沟通等模块在内的SWOR,器官移植受者通过受者端在上述模块录入相关内容,随访团队通过医生端随机选取器官移植受者查看上述模块录入的内容和有关数据时间曲线。结果自2019年3月至2024年5月,参与试用的器官移植受者共1730例,其中男性1235例,女性477例。成年受者1648例,未成年受者82例。参与试用的器官移植受者含括了所有器官移植类型,其中肝移植、肾移植、肺脏移植、心脏移植、胰腺移植、小肠移植和联合器官移植分别占比57.5%、28.2%、6.13%、2.83%、0.17%、0.06%和5.14%。自医生端随机抽取系统内器官移植受者进行查看,上述模块内容和随访指标均能很好的呈现,有关数据可呈现时间曲线。结论该研究初步证明了SWOR可以为器官移植受者提供较为实用的数字化健康管理。展开更多
目的:探讨circRNA_0016418及circRNA_0017247异常表达对恶性黑色素瘤诊断及其预测淋巴结转移的价值。方法:选取2018年01月至2021年10月我院收治的68例恶性黑色素瘤患者,将其分为淋巴结转移组26例和无淋巴结转移组42例。采用实时荧光定量...目的:探讨circRNA_0016418及circRNA_0017247异常表达对恶性黑色素瘤诊断及其预测淋巴结转移的价值。方法:选取2018年01月至2021年10月我院收治的68例恶性黑色素瘤患者,将其分为淋巴结转移组26例和无淋巴结转移组42例。采用实时荧光定量PCR法检测恶性黑色素瘤组织及正常组织中circRNA_0016418及circRNA_0017247的水平。应用受试者工作特征(receiver operating characteristic, ROC)曲线分析circRNA_0016418及circRNA_0017247异常表达对恶性黑色素瘤诊断及其预测淋巴结转移的价值。Pearson相关分析检测恶性黑色素瘤患者中circRNA_0016418水平与circRNA_0017247水平的相关性。结果:恶性黑色素瘤组织中circRNA_0016418水平(2.64±1.17 vs 0.95±0.36)及circRNA_0017247水平(5.18±2.50 vs 1.52±0.63)均明显高于正常组织(P<0.001)。淋巴结转移组circRNA_0016418水平(3.85±1.72 vs 1.66±0.74)及circRNA_0017247水平(7.16±3.82 vs 3.38±1.54)均明显高于无淋巴结转移组(P<0.001)。ROC曲线显示,circRNA_0016418及circRNA_0017247二者联合诊断恶性黑色素瘤的曲线下面积为0.905(95%CI:0.847~0.964),其灵敏度为92.8%,特异度为83.5%;二者联合预测淋巴结转移的曲线下面积为0.957(95%CI:0.895~0.993),其灵敏度为98.0%,特异度为84.6%。相关分析显示,恶性黑色素瘤患者circRNA_0016418水平与circRNA_0017247水平呈正相关(r=0.802,P<0.001)。结论:恶性黑色素瘤组织中circRNA_0016418及circRNA_0017247水平明显升高,与淋巴结转移有关,二者联合检测对恶性黑色素瘤诊断及其预测淋巴结转移有很好的价值。展开更多
文摘Experimental investigations were conducted on the adsorption characteristics of 2,6-dichlorophenol by two hypercrosslinked resins ZH-01 and XAD-4. The static adsorption was studied. Within temperature range of 288K-313K, the equilibrium adsorption date was fitted to freundlich adsorption isotherm models to evaluate the model parameters. The enthalpies, free energy, entropy were indicative of an exothermic, a spontaneous and disorder decreasing process. The magnitudes for 2,6-dichlorophenol on ZH-01 showed a chemisorption＇s transitions while on XAD-4 shows a physical adsorption process. The results showed that the ZH-01 adsorbents were better than the Amberlite XAD-4 for removing the 2,6-dichlorophenol in aqueous solutions.
文摘目的搭建器官移植受者全生命周期数字化健康管理系统(the system for the whole life-cycle management of organ transplant recipient,SWOR),总结试用SWOR经验。方法利用智能手机应用程序(application,APP)和微信小程序,搭建包括诊疗过程、日常指标、检查结果、影像报告、用药方案和医患沟通等模块在内的SWOR,器官移植受者通过受者端在上述模块录入相关内容,随访团队通过医生端随机选取器官移植受者查看上述模块录入的内容和有关数据时间曲线。结果自2019年3月至2024年5月,参与试用的器官移植受者共1730例,其中男性1235例,女性477例。成年受者1648例,未成年受者82例。参与试用的器官移植受者含括了所有器官移植类型,其中肝移植、肾移植、肺脏移植、心脏移植、胰腺移植、小肠移植和联合器官移植分别占比57.5%、28.2%、6.13%、2.83%、0.17%、0.06%和5.14%。自医生端随机抽取系统内器官移植受者进行查看,上述模块内容和随访指标均能很好的呈现,有关数据可呈现时间曲线。结论该研究初步证明了SWOR可以为器官移植受者提供较为实用的数字化健康管理。
文摘目的:探讨circRNA_0016418及circRNA_0017247异常表达对恶性黑色素瘤诊断及其预测淋巴结转移的价值。方法:选取2018年01月至2021年10月我院收治的68例恶性黑色素瘤患者,将其分为淋巴结转移组26例和无淋巴结转移组42例。采用实时荧光定量PCR法检测恶性黑色素瘤组织及正常组织中circRNA_0016418及circRNA_0017247的水平。应用受试者工作特征(receiver operating characteristic, ROC)曲线分析circRNA_0016418及circRNA_0017247异常表达对恶性黑色素瘤诊断及其预测淋巴结转移的价值。Pearson相关分析检测恶性黑色素瘤患者中circRNA_0016418水平与circRNA_0017247水平的相关性。结果:恶性黑色素瘤组织中circRNA_0016418水平(2.64±1.17 vs 0.95±0.36)及circRNA_0017247水平(5.18±2.50 vs 1.52±0.63)均明显高于正常组织(P<0.001)。淋巴结转移组circRNA_0016418水平(3.85±1.72 vs 1.66±0.74)及circRNA_0017247水平(7.16±3.82 vs 3.38±1.54)均明显高于无淋巴结转移组(P<0.001)。ROC曲线显示,circRNA_0016418及circRNA_0017247二者联合诊断恶性黑色素瘤的曲线下面积为0.905(95%CI:0.847~0.964),其灵敏度为92.8%,特异度为83.5%;二者联合预测淋巴结转移的曲线下面积为0.957(95%CI:0.895~0.993),其灵敏度为98.0%,特异度为84.6%。相关分析显示,恶性黑色素瘤患者circRNA_0016418水平与circRNA_0017247水平呈正相关(r=0.802,P<0.001)。结论:恶性黑色素瘤组织中circRNA_0016418及circRNA_0017247水平明显升高,与淋巴结转移有关,二者联合检测对恶性黑色素瘤诊断及其预测淋巴结转移有很好的价值。
