The development of multimodal molecular imaging contrast agents based on versatile nanomaterials has recently attracted much attention in disease diagnosis and therapeutic delivery.Contrast agents made from nanopartic...The development of multimodal molecular imaging contrast agents based on versatile nanomaterials has recently attracted much attention in disease diagnosis and therapeutic delivery.Contrast agents made from nanoparticles and used for multimodal imaging in vivo provide a multidimensional pathophysiological overview of diseases.This review summarizes recently developed advanced nanomaterials for multimodal molecular imaging.We comprehensively discuss these nanoparticle contrast agents in terms of their targeting modalities,limitations in clinical translation and future directions.展开更多
基金This work was supported by the National Key Research and Development Program of China(No.2020YFA0909000)the National Natural Science Foundation of China(No.91959102)+1 种基金the Shanghai Rising-Star Program,China(No.19QA1405400)the Postdoctoral Science Foundation of Zhejiang Province,China(No.ZJ2020131).
文摘The development of multimodal molecular imaging contrast agents based on versatile nanomaterials has recently attracted much attention in disease diagnosis and therapeutic delivery.Contrast agents made from nanoparticles and used for multimodal imaging in vivo provide a multidimensional pathophysiological overview of diseases.This review summarizes recently developed advanced nanomaterials for multimodal molecular imaging.We comprehensively discuss these nanoparticle contrast agents in terms of their targeting modalities,limitations in clinical translation and future directions.