Background There is little information on the factors that have influenced the long-term success rate of radiofrequency ablation of ventricular arrhythmias(VAs)at different targets.The objective of this study was to i...Background There is little information on the factors that have influenced the long-term success rate of radiofrequency ablation of ventricular arrhythmias(VAs)at different targets.The objective of this study was to investigate the characteristics of the ablation of VAs and the factors influencing the long-term success rate in our center.Methods Totally,2751 consecutive patients(mean ages 44±15 years,male/female 58.6%/41.4%)with VAs underwent radiofrequency ablation in Guangdong Provincial People’s Hospital from 2013 to 2018 were analyzed.Baseline data were retrieved from the medical record system.Long-term follow-up data were obtained by telephone interview.We mainly recorded the patient’s last post-ablation holter,and the symptoms after ablation.Multivariable regressions were applied to assess the relationship between the long-term success rate and the influence factors.Results Through the baseline data of 2751 patients,we found that the acute success rate of ablation was 95.1%.The average follow-up time was 16±5 months(ranging from 1 to 80).In all,304 patients(11%)lost follow-up,while 2447 patients(89%)were successfully followed.The long-term success rate of ablation was 82.56%.By means of multivariable regression analyses,it was discovered that cardiovascular diseases,such as coronary heart disease(OR:0.568,95%CI:0.327-0.987),hypertension(OR:1.554,95%CI:1.100-2.198),were independently associated with the long-term success rate,as well as ablation approaches(OR:0.212,95%CI:0.082-0.550).Lower ablation success rates of the patients whose VAs were originated from some uncommon region,like left ventricular papillary muscle,Summit,etc.were observed.Conclusions Ablation approaches,concomitant cardiovascular diseases,and ablation targets were related to the long-term clinical outcome of VAs ablation.展开更多
Background Hospital-acquired pneumonia （HAP） is the most common and most serious nosocomial infection for cardiac surgery patients, with high incidence and fatality ratel. It is important for cardiac surgeons to cor...Background Hospital-acquired pneumonia （HAP） is the most common and most serious nosocomial infection for cardiac surgery patients, with high incidence and fatality ratel. It is important for cardiac surgeons to correctly identify HAP, assess the severity, and then adjust anti-infection method, which can reduce the mortality rate, shorten hospitalization time, and reduce the waste of medical resources. The purpose of this research is to evaluate the application value of lung CT in diagnosis and treatment of HAP after cardiac surgery. Methods A retrospective analysis was conducted for clinical data about 76 cardiac surgery patients who were diagnosed with HAP during January to December 2013. The clinical data mainly included symptoms, physical signs, laboratory examinations （such as routine blood tests and serum procalcitonin）, and lung CT and X-ray data. Our focus is on the comparison between lung CT and X-ray data. Results The positive diagnostic rate, false negative rate, and false positive rate of lung CT were 71/76 （93.4%）, 5/76 （6.6%）, and 1/76 （1.3%） respectively. The coincidence rate of X-ray and CT was 45/76 （59.2%）, and the false negative rate of X-ray was 23/76 （30.3%）. Conclusion Lung CT is better than X-ray in diagnosis of HAP after cardiac surgery and assessment of severity, and has greater significance for guiding the rational useof antibiotics. Therefore, lung CT is worthy of application and popularization.展开更多
文摘Background There is little information on the factors that have influenced the long-term success rate of radiofrequency ablation of ventricular arrhythmias(VAs)at different targets.The objective of this study was to investigate the characteristics of the ablation of VAs and the factors influencing the long-term success rate in our center.Methods Totally,2751 consecutive patients(mean ages 44±15 years,male/female 58.6%/41.4%)with VAs underwent radiofrequency ablation in Guangdong Provincial People’s Hospital from 2013 to 2018 were analyzed.Baseline data were retrieved from the medical record system.Long-term follow-up data were obtained by telephone interview.We mainly recorded the patient’s last post-ablation holter,and the symptoms after ablation.Multivariable regressions were applied to assess the relationship between the long-term success rate and the influence factors.Results Through the baseline data of 2751 patients,we found that the acute success rate of ablation was 95.1%.The average follow-up time was 16±5 months(ranging from 1 to 80).In all,304 patients(11%)lost follow-up,while 2447 patients(89%)were successfully followed.The long-term success rate of ablation was 82.56%.By means of multivariable regression analyses,it was discovered that cardiovascular diseases,such as coronary heart disease(OR:0.568,95%CI:0.327-0.987),hypertension(OR:1.554,95%CI:1.100-2.198),were independently associated with the long-term success rate,as well as ablation approaches(OR:0.212,95%CI:0.082-0.550).Lower ablation success rates of the patients whose VAs were originated from some uncommon region,like left ventricular papillary muscle,Summit,etc.were observed.Conclusions Ablation approaches,concomitant cardiovascular diseases,and ablation targets were related to the long-term clinical outcome of VAs ablation.
基金supported by the National Natural Science Fund(No.81300034)
文摘Background Hospital-acquired pneumonia （HAP） is the most common and most serious nosocomial infection for cardiac surgery patients, with high incidence and fatality ratel. It is important for cardiac surgeons to correctly identify HAP, assess the severity, and then adjust anti-infection method, which can reduce the mortality rate, shorten hospitalization time, and reduce the waste of medical resources. The purpose of this research is to evaluate the application value of lung CT in diagnosis and treatment of HAP after cardiac surgery. Methods A retrospective analysis was conducted for clinical data about 76 cardiac surgery patients who were diagnosed with HAP during January to December 2013. The clinical data mainly included symptoms, physical signs, laboratory examinations （such as routine blood tests and serum procalcitonin）, and lung CT and X-ray data. Our focus is on the comparison between lung CT and X-ray data. Results The positive diagnostic rate, false negative rate, and false positive rate of lung CT were 71/76 （93.4%）, 5/76 （6.6%）, and 1/76 （1.3%） respectively. The coincidence rate of X-ray and CT was 45/76 （59.2%）, and the false negative rate of X-ray was 23/76 （30.3%）. Conclusion Lung CT is better than X-ray in diagnosis of HAP after cardiac surgery and assessment of severity, and has greater significance for guiding the rational useof antibiotics. Therefore, lung CT is worthy of application and popularization.
