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乳腺癌生存结果性别差异与肿瘤亚型的关系 被引量:3
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作者 张莉 廖梦迪 +1 位作者 邹尔夏 李晶 《临床外科杂志》 2022年第12期1159-1166,共8页
目的通过对男性乳腺癌和女性乳腺癌病人进行基于人群的最大规模的比较研究,探讨乳腺癌生存结果性别差异与肿瘤亚型的关系。方法利用2010~2012年美国疾病监测、流行病学和最终结果(SEER)项目获得的数据,进行一项基于人群的回顾性队列研究... 目的通过对男性乳腺癌和女性乳腺癌病人进行基于人群的最大规模的比较研究,探讨乳腺癌生存结果性别差异与肿瘤亚型的关系。方法利用2010~2012年美国疾病监测、流行病学和最终结果(SEER)项目获得的数据,进行一项基于人群的回顾性队列研究,调查男性和女性在肿瘤亚型、总体生存率(OS)和乳腺癌特异性死亡率(BCSM)的差异。结果181814例乳腺癌病人(男性1516例,女性180298例)符合本研究。男性病人多为黑人,年龄大,组织学分级较低、分期较晚,肿瘤直径较大,淋巴结和远处转移较多,人表皮生长因子受体2(HER2)阴性(P<0.05)。配对分析显示,男性和女性病人的2年OS分别为91.2%和93.7%,BCSM分别为2.2%和2.5%。单因素分析显示,男性三阴性(TN)、激素受体(HoR)阳性/HER2阳性和HoR阳性/HER2阴性病人的OS较差(P<0.01)。同时,HoR阳性/HER2阳性和TN亚型与男性病人的BCSM显著相关(P<0.01)。多因素分析显示,男性TNBC病人的OS和BCSM较差(P<0.05)。同时,结果显示,在调整其他因素后,HoR阳性/HER2阴性亚组中的男性病人死于BC的可能性较小(P<0.05)。结论乳腺癌亚型的2年OS和BCSM分析显示,TN亚型的男性乳腺癌和女性乳腺癌病人有明显的差异。 展开更多
关键词 乳腺癌 生存结果 性别差异 肿瘤亚型
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“海上丝绸之路”沿线重要港口区位优势度评估 被引量:22
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作者 牟乃夏 廖梦迪 +2 位作者 张恒才 彭澎 刘希亮 《地球信息科学学报》 CSCD 北大核心 2018年第5期613-622,共10页
评估"海上丝绸之路"沿线港口的区位优势度,对于港口及其腹地基础设施合理规划、港口未来投资预判以及推进"一带一路"倡议有重要意义。本文从海陆联运的视角出发,综合考虑港口腹地的路网密度、交通干线影响度、城市... 评估"海上丝绸之路"沿线港口的区位优势度,对于港口及其腹地基础设施合理规划、港口未来投资预判以及推进"一带一路"倡议有重要意义。本文从海陆联运的视角出发,综合考虑港口腹地的路网密度、交通干线影响度、城市影响度、航运战略枢纽影响度和航运战略通道影响度等五个因素,构建港口区位优势度评价模型来对"海上丝绸之路"沿线重要港口进行区位优势度分析。研究发现:(1)"海上丝绸之路"沿线港口的区位优势度区域化差异显著,从东向西总体呈"高-低-高"的空间分布格局;(2)从世界分区的视角看,东南亚区域港口区位优势最高,其次为南欧至西欧、南亚、北非、西亚等地区,东非至南非区域港口区位优势度最低;(3)港口各区位影响因素的评价结果空间分布特征差异显著,其中港口区位优势度分布特征与交通干线影响度、城市影响度的相关性较大。研究结果可为海外港口基础设施的投资建设过程提供科学支撑。 展开更多
关键词 海上丝绸之路 海洋运输 重要港口 区位优势 海陆联运 空间格局
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Spatial pattern of location advantages of ports along the Maritime Silk Road 被引量:2
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作者 MOU Naixia WANG Chunying +3 位作者 CHEN Jinhai YANG Tengfei ZHANG Lingxian liao mengdi 《Journal of Geographical Sciences》 SCIE CSCD 2021年第1期149-176,共28页
Location advantages of ports refer to the current developments of ports based on their conditions, such as geographic location, traffic accessibility and hinterland economy, etc., and the spatial pattern of ports’ lo... Location advantages of ports refer to the current developments of ports based on their conditions, such as geographic location, traffic accessibility and hinterland economy, etc., and the spatial pattern of ports’ location advantages reflects the spatial distributions, the regularities and the correlations among their conditions for development. A good understanding of the spatial patterns of ports’ location advantages can help to better identify the relative advantages of ports, position ports’ functions and make strategic plans for development. This paper selected 1259 ports from 63 countries along the Maritime Silk Road as research objects and builds an accessing model to analyze their location advantages on the bases of six factors: the influence of strategic shipping pivot, the competitiveness of port location potential, port network status, the influence of city, the influence of traffic trunk, and road network density in hinterland. The study has the following three findings. Firstly, the location advantages of ports show a 'high-low-high' distribution pattern from the west to the east, displaying an obvious 'core-periphery' regionalized distribution. Secondly, most ports have high location advantages, mainly located in Strait of Malacca, the United Arab Emirates, northern Mediterranean coastal region and China-Japan region, the top 10 ports are mainly located in Singapore, China, Malaysia and Japan, indicating that the shipping industry in Asia-Pacific region has stepped to the far front of the global competition;slow economic growths, wars, far away from the Belt and Road countries or bad climate have low location advantages, mainly located in African coastal areas, Oceania, Northeast Europe and Russia. Thirdly, compared with the landward location advantages, the seaward location advantages have a higher influence, and different indicators of location advantages have different influences on the evaluation results, the competitiveness of port location potential being the core indicator. 展开更多
关键词 Maritime Silk Road location advantages ports shipping network spatial patterns
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