Myocytes power the movement of all organs in the body.Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases.Apigenin,a kind of flavone,is being used to treat many disorders....Myocytes power the movement of all organs in the body.Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases.Apigenin,a kind of flavone,is being used to treat many disorders.It exerts a host of different pharmacological activities,such as anti-inflammatory,anti-mutagenic,cardioprotective,and antioxidant effects.Accordingly,apigenin is considered a promising candidate for myocyte protection.In this review,we introduced the characteristics of apigenin.The means of apigenin protection of myocytes as well as the mechanism were summarized and discussed.The protective effects can be classified into proliferation-promoting,anti-inflammatory,atrophy-preventing,metabolism-increasing,and antioxidative effects.Additionally,we provided some outlook on the valuable applications of apigenin in sports medicine,which eagerly require further fundamental research.展开更多
基金supported by the China Postdoctoral Science Foundation(Grant No.2019M653494)Special Field Projects of Guizhou Education Committee(Grant No.KY2019072)High-level Innovative Talents in Guizhou Province(Grant No.2018-2016-023).
文摘Myocytes power the movement of all organs in the body.Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases.Apigenin,a kind of flavone,is being used to treat many disorders.It exerts a host of different pharmacological activities,such as anti-inflammatory,anti-mutagenic,cardioprotective,and antioxidant effects.Accordingly,apigenin is considered a promising candidate for myocyte protection.In this review,we introduced the characteristics of apigenin.The means of apigenin protection of myocytes as well as the mechanism were summarized and discussed.The protective effects can be classified into proliferation-promoting,anti-inflammatory,atrophy-preventing,metabolism-increasing,and antioxidative effects.Additionally,we provided some outlook on the valuable applications of apigenin in sports medicine,which eagerly require further fundamental research.
