The effects of exogenous NO on Eimeria tenella oocysts were studied. The E. tenella oocysts freshly isolated from feces of experimental chickens infected with E. tenella and sporulated E. tenella oocysts were treated ...The effects of exogenous NO on Eimeria tenella oocysts were studied. The E. tenella oocysts freshly isolated from feces of experimental chickens infected with E. tenella and sporulated E. tenella oocysts were treated in vitro by the well-known NO-donors, SNP, SPER/NO and GSNO. The results showed that among the 3 NO donors, only GSNO had significant effects on the percentage of sporulated oocysts, the inhibiting rate of purified oocysts was from 93 to 97%, and reached 100% on the oocysts in the feces of chickens with E. tenella infection. GSNO also significantly decreased the virulence of E. tenella oocysts, and the oocysts treated by 2 - 8 mmol L-1 GSNO almost lost their pathogenicity to chickens.展开更多
基金The study was supported by National Natural Science Foundation of China(39970564).
文摘The effects of exogenous NO on Eimeria tenella oocysts were studied. The E. tenella oocysts freshly isolated from feces of experimental chickens infected with E. tenella and sporulated E. tenella oocysts were treated in vitro by the well-known NO-donors, SNP, SPER/NO and GSNO. The results showed that among the 3 NO donors, only GSNO had significant effects on the percentage of sporulated oocysts, the inhibiting rate of purified oocysts was from 93 to 97%, and reached 100% on the oocysts in the feces of chickens with E. tenella infection. GSNO also significantly decreased the virulence of E. tenella oocysts, and the oocysts treated by 2 - 8 mmol L-1 GSNO almost lost their pathogenicity to chickens.
