人群在城市内部空间中的流动是社会活力和资源分配的直接体现,是城市交通规划管理的重要依据。融合手机信令大数据和POI(point of interests)数据,对福州市主城区内的交通小区进行功能分区并构建了交通小区之间的空间交互网络,采用复杂...人群在城市内部空间中的流动是社会活力和资源分配的直接体现,是城市交通规划管理的重要依据。融合手机信令大数据和POI(point of interests)数据,对福州市主城区内的交通小区进行功能分区并构建了交通小区之间的空间交互网络,采用复杂网络方法对各类型功能区的中心性地位及出行距离衰减效应进行了分析。结果表明:福州市主城区功能区以居住及公共服务相关功能区为主。鼓楼区和台江区的人流量最为活跃,仓山区及晋安区的内部空间交互格局存在显著的不平衡现象。各功能区的中心性地位存在明显的空间和周期差异,科教文化及商服类型功能区的中心性普遍较高。居住用地与其他功能区之间的距离衰减效应受到时段的影响较大。基于以上结果可对城市公共交通优化提供一定支持。展开更多
Opisina arenosella has been an outbreak pest of coconut trees in southern China since 2013. To develop efficient control methods for this invasive pest, adequate rearing protocols are desirable. In this study, an orth...Opisina arenosella has been an outbreak pest of coconut trees in southern China since 2013. To develop efficient control methods for this invasive pest, adequate rearing protocols are desirable. In this study, an orthogonal array of artificial diets with 11 factors at 3 levels was deployed for both 2 nd–4 th and 5 th–6 th instar larvae of O. arenosella. Biological parameters including survival time of larvae, development time from larva to pupa, pupation rate, emergence rate, and pupal weight were monitored to reveal the most important components in the diet formulas. Biological parameters in O. arenosella were most affected by brewer’s yeast, sucrose, ascorbic acid, and wheat germ. Statistical analysis indicated that different diet combinations supported optimum performance of biological parameters for 2 nd–4 th and 5 th–6 th instar larvae. The validity of the optimization predicted by the orthogonal array analysis was confirmed in a follow-up bioassay with similar optimized diets for both 2 nd–4 th and 5 th–6 th instar larvae. The optimal artificial diet has great potential for the mass rearing technique, and can provide valuable results for using parasitoids in biological control of O. arenosella.展开更多
Background The mutation of the tyrosinase （TYR） gene results in oculocutaneous albinism type 1 （OCA1）, an autosomal recessive genetic disorder. OCA1 is the most common type of OCA in the Chinese population. Hence,...Background The mutation of the tyrosinase （TYR） gene results in oculocutaneous albinism type 1 （OCA1）, an autosomal recessive genetic disorder. OCA1 is the most common type of OCA in the Chinese population. Hence, the TYR gene was tested in this study. We also delineated the genetic analysis of OCA1 in a Chinese family. Methods Genomic DNA was isolated from the blood leukocytes of a proband and his family. Mutational analysis at the TYR locus by DNA sequencing was used to screen five exons, including the intron/exon junctions. A pedigree chart was drawn and the fundus of the eyes of the proband was also examined. Results A novel missense mutation p.1151S on exon 1, and homozygous TYR mutant alleles were identified in the proband. None of the mutants was identified among the 100 normal control subjects. Genetic analysis of the proband＇s wife showed normal alleles in the TYR gene. Thus, the fetus was predicated a carrier of OCA1 with a normal appearance. Conclusion This study provided new information about a novel mutation, p.1151S, in the TYR gene in a Chinese family with OCAI. Further investigation of the proband would be helpful to determine the effects of this mutation on TYR activity.展开更多
文摘人群在城市内部空间中的流动是社会活力和资源分配的直接体现,是城市交通规划管理的重要依据。融合手机信令大数据和POI(point of interests)数据,对福州市主城区内的交通小区进行功能分区并构建了交通小区之间的空间交互网络,采用复杂网络方法对各类型功能区的中心性地位及出行距离衰减效应进行了分析。结果表明:福州市主城区功能区以居住及公共服务相关功能区为主。鼓楼区和台江区的人流量最为活跃,仓山区及晋安区的内部空间交互格局存在显著的不平衡现象。各功能区的中心性地位存在明显的空间和周期差异,科教文化及商服类型功能区的中心性普遍较高。居住用地与其他功能区之间的距离衰减效应受到时段的影响较大。基于以上结果可对城市公共交通优化提供一定支持。
基金supported by the National Key Research and Development Program of China (2016YFC1201200)the National Key Technologies R&D Program of China during the 12th Five-Year Plan period (2015BAD08B03)the Central Public-interest Scientific Institution Basic ResearchFund for Chinese Academy of Tropical Agricultural Sciences (1630042017013 and 1630042017012)
文摘Opisina arenosella has been an outbreak pest of coconut trees in southern China since 2013. To develop efficient control methods for this invasive pest, adequate rearing protocols are desirable. In this study, an orthogonal array of artificial diets with 11 factors at 3 levels was deployed for both 2 nd–4 th and 5 th–6 th instar larvae of O. arenosella. Biological parameters including survival time of larvae, development time from larva to pupa, pupation rate, emergence rate, and pupal weight were monitored to reveal the most important components in the diet formulas. Biological parameters in O. arenosella were most affected by brewer’s yeast, sucrose, ascorbic acid, and wheat germ. Statistical analysis indicated that different diet combinations supported optimum performance of biological parameters for 2 nd–4 th and 5 th–6 th instar larvae. The validity of the optimization predicted by the orthogonal array analysis was confirmed in a follow-up bioassay with similar optimized diets for both 2 nd–4 th and 5 th–6 th instar larvae. The optimal artificial diet has great potential for the mass rearing technique, and can provide valuable results for using parasitoids in biological control of O. arenosella.
基金This study was supported in part by grants from the Natural Science Foundation of Beijing （No. 7092040）, the Capital Medical Development Foundation （No. 2007-3111）, and the National Natural Science Foundation of China （No. 31071252）.
文摘Background The mutation of the tyrosinase （TYR） gene results in oculocutaneous albinism type 1 （OCA1）, an autosomal recessive genetic disorder. OCA1 is the most common type of OCA in the Chinese population. Hence, the TYR gene was tested in this study. We also delineated the genetic analysis of OCA1 in a Chinese family. Methods Genomic DNA was isolated from the blood leukocytes of a proband and his family. Mutational analysis at the TYR locus by DNA sequencing was used to screen five exons, including the intron/exon junctions. A pedigree chart was drawn and the fundus of the eyes of the proband was also examined. Results A novel missense mutation p.1151S on exon 1, and homozygous TYR mutant alleles were identified in the proband. None of the mutants was identified among the 100 normal control subjects. Genetic analysis of the proband＇s wife showed normal alleles in the TYR gene. Thus, the fetus was predicated a carrier of OCA1 with a normal appearance. Conclusion This study provided new information about a novel mutation, p.1151S, in the TYR gene in a Chinese family with OCAI. Further investigation of the proband would be helpful to determine the effects of this mutation on TYR activity.
