目的测定梅州地区2型糖尿病(T2DM)患者血清超氧化物歧化酶(SOD)水平,并分析其影响因素。方法方便选取2019年3—12月期间T2DM患者(T2DM组)212例和健康体检者(对照组)210名,测定血清SOD、糖化血红蛋白(HbA1c)、葡萄糖(Glu)、胰岛素C肽(C-P...目的测定梅州地区2型糖尿病(T2DM)患者血清超氧化物歧化酶(SOD)水平,并分析其影响因素。方法方便选取2019年3—12月期间T2DM患者(T2DM组)212例和健康体检者(对照组)210名,测定血清SOD、糖化血红蛋白(HbA1c)、葡萄糖(Glu)、胰岛素C肽(C-P)及胰岛素(Ins)水平,并进行统计学分析。结果T2DM组血清SOD水平显著低于对照组[208(186~234)U/mL vs 213(180~252)U/mL,差异有统计学意义(U=44.624,P<0.010);在T2DM组中,男性与女性的血清SOD水平[209(184~229)U/mL vs 206(186~252)U/mL],差异无统计学意义(t=1.529,P>0.05);T2DM组中,各年龄段血清SOD水平有显著性差异,且血清SOD水平与年龄呈负相关(r=-0.267,P<0.010);回归分析显示,血清SOD水平降低与HbA1c水平相关。结论T2DM患者的血清SOD水平较正常人低,且主要与年龄与HbA1c水平相关。展开更多
Previous research reveals that the genome structures of rhizobial type strains and reference strains can reflect their phylogenetic relationships. In order to further explore the potential application of genome struct...Previous research reveals that the genome structures of rhizobial type strains and reference strains can reflect their phylogenetic relationships. In order to further explore the potential application of genome structure as a phylogenetic marker in rhizobial natural taxonomy, this study analyzed the genome structures of 29 unclassified nodule bacteria isolated from the root nodules of leguminous trees, Robinia sp., Dalbergia spp., and A lbizia spp. and 7 rhizobial reference strains by I-CeuI cleavage, then clustered these bacteria phylogenetically based on their genome structures and compared these clusters with those based on numerical taxonomy and 16S rDNA PCR-RFLP. Eleven phylogenetic clusters were obtained, The clusters were in large part consistent with those based on numerical taxonomy and 16S rDNA PCR-RFLP. Also there are inconsistent clusters based on the above three methods. But results are completely consistent with 16S rRNA clusters. This suggested that the genome structure clustering method can be used to lastly identify root nodule isolates and detect their phylogenetic relationships. The credibility and repeatability of the results, together with the simplicity and possibility to analyze a large number of strains in a short time of the method, indicates the broad potential application of genome structure as phylogenetic marker to categorize rhizobial isolates and should in the future facilitate biodiversity studies.展开更多
Superconducting quantum interference devices(SQUlDs)using YBa2Cu3O7step-edge grain boundary junctions on LaAlO3 substrates were fabricated.The Ⅰ-Ⅴ and V-Ф characteristics of these step-junction dc-SQUIDS were studi...Superconducting quantum interference devices(SQUlDs)using YBa2Cu3O7step-edge grain boundary junctions on LaAlO3 substrates were fabricated.The Ⅰ-Ⅴ and V-Ф characteristics of these step-junction dc-SQUIDS were studied.A-modulation voltage exceeding 16μV was attained with Ls=60pH at 77K.At 77K,a square washer configuration with inductance L_(s)=150pH yields flux noise of about 5.08×10^(-5)Ф_(0)/√Hz at frequencies above 100Hz,increasing to 1.1×10^(-4)Ф0/√Hz below 1 Hz.The corresponding magnetic field and energy resolution were 270 fT/√Hz and 3.68×10^(-29)J/Hz respectively,above 100 Hz,and increasing to 710 fT/√Hz and 1.8×10^(-28) J/Hz over a signal frequency range to below 1 Hz.展开更多
Cubic （Zn,Li）TiO3 powders were synthesized through a modified sol-gel route including the Pechini process via a three-step heat treatment.The as-synthesized （Zn,Li）TiO3 could be stable up to 1000 °C.The diele...Cubic （Zn,Li）TiO3 powders were synthesized through a modified sol-gel route including the Pechini process via a three-step heat treatment.The as-synthesized （Zn,Li）TiO3 could be stable up to 1000 °C.The dielectric constant and dielectric loss tangent of all the synthesized （Zn,Li）TiO3 samples at different measurement frequencies showed the similar tendency.At the same frequency,the dielectric constant and the dielectric loss tangent of （Zn,Li）TiO3 samples decreased and increased,respectively,with the lithium doping content increase.The as-prepared （Zn,Li）TiO3 showed improved microwave dielectric properties,and its maximum value of quality factor could reach 34000 GHz.展开更多
文摘目的测定梅州地区2型糖尿病(T2DM)患者血清超氧化物歧化酶(SOD)水平,并分析其影响因素。方法方便选取2019年3—12月期间T2DM患者(T2DM组)212例和健康体检者(对照组)210名,测定血清SOD、糖化血红蛋白(HbA1c)、葡萄糖(Glu)、胰岛素C肽(C-P)及胰岛素(Ins)水平,并进行统计学分析。结果T2DM组血清SOD水平显著低于对照组[208(186~234)U/mL vs 213(180~252)U/mL,差异有统计学意义(U=44.624,P<0.010);在T2DM组中,男性与女性的血清SOD水平[209(184~229)U/mL vs 206(186~252)U/mL],差异无统计学意义(t=1.529,P>0.05);T2DM组中,各年龄段血清SOD水平有显著性差异,且血清SOD水平与年龄呈负相关(r=-0.267,P<0.010);回归分析显示,血清SOD水平降低与HbA1c水平相关。结论T2DM患者的血清SOD水平较正常人低,且主要与年龄与HbA1c水平相关。
基金985 Foundation Grant from Peking University Health Science Center
文摘Previous research reveals that the genome structures of rhizobial type strains and reference strains can reflect their phylogenetic relationships. In order to further explore the potential application of genome structure as a phylogenetic marker in rhizobial natural taxonomy, this study analyzed the genome structures of 29 unclassified nodule bacteria isolated from the root nodules of leguminous trees, Robinia sp., Dalbergia spp., and A lbizia spp. and 7 rhizobial reference strains by I-CeuI cleavage, then clustered these bacteria phylogenetically based on their genome structures and compared these clusters with those based on numerical taxonomy and 16S rDNA PCR-RFLP. Eleven phylogenetic clusters were obtained, The clusters were in large part consistent with those based on numerical taxonomy and 16S rDNA PCR-RFLP. Also there are inconsistent clusters based on the above three methods. But results are completely consistent with 16S rRNA clusters. This suggested that the genome structure clustering method can be used to lastly identify root nodule isolates and detect their phylogenetic relationships. The credibility and repeatability of the results, together with the simplicity and possibility to analyze a large number of strains in a short time of the method, indicates the broad potential application of genome structure as phylogenetic marker to categorize rhizobial isolates and should in the future facilitate biodiversity studies.
基金Supported in part by the National Natural Science Foundation of China under Grant No.6937019.
文摘Superconducting quantum interference devices(SQUlDs)using YBa2Cu3O7step-edge grain boundary junctions on LaAlO3 substrates were fabricated.The Ⅰ-Ⅴ and V-Ф characteristics of these step-junction dc-SQUIDS were studied.A-modulation voltage exceeding 16μV was attained with Ls=60pH at 77K.At 77K,a square washer configuration with inductance L_(s)=150pH yields flux noise of about 5.08×10^(-5)Ф_(0)/√Hz at frequencies above 100Hz,increasing to 1.1×10^(-4)Ф0/√Hz below 1 Hz.The corresponding magnetic field and energy resolution were 270 fT/√Hz and 3.68×10^(-29)J/Hz respectively,above 100 Hz,and increasing to 710 fT/√Hz and 1.8×10^(-28) J/Hz over a signal frequency range to below 1 Hz.
基金Supported by the National Natural Science Foundation of China(Nos.20731001,20871015 and 50725415)the Program for New Century Excellent Talents in University,China(NCET)+1 种基金the National Basic Research Program of China(No.2007CB613601)the Program for Changjiang Scholars and Innovative Research Team in University,China(No.IRT0708)
文摘Cubic （Zn,Li）TiO3 powders were synthesized through a modified sol-gel route including the Pechini process via a three-step heat treatment.The as-synthesized （Zn,Li）TiO3 could be stable up to 1000 °C.The dielectric constant and dielectric loss tangent of all the synthesized （Zn,Li）TiO3 samples at different measurement frequencies showed the similar tendency.At the same frequency,the dielectric constant and the dielectric loss tangent of （Zn,Li）TiO3 samples decreased and increased,respectively,with the lithium doping content increase.The as-prepared （Zn,Li）TiO3 showed improved microwave dielectric properties,and its maximum value of quality factor could reach 34000 GHz.
