In June 2003 and 2006 concentrations of nutrient were determined in the Changjiang Estuary. The data indicated that phosphate and nitrate did not behave conservatively in the estuary, but silicate behaved conservative...In June 2003 and 2006 concentrations of nutrient were determined in the Changjiang Estuary. The data indicated that phosphate and nitrate did not behave conservatively in the estuary, but silicate behaved conservatively. An important mobilization of phosphate and nitrate was observed from the river up to halfway in the estuary. Both input flux (from river to estuary) and output flux (from estuary to coastal zone) of phosphate, silicate and nitrate were calculated from statistical interpretations of the salinity profiles. There was a large discrepancy between input and output fluxes of phosphate and nitrate. The river fluxes of silicate, phosphate and nitrate (fr) are augmented 5.3%, 28.9% and 36.6% in June 2003 and 1.0%, 62.5%, 31.7% in June 2006 by internal inputs (fi).The phosphate and nitrate fluxes are enhanced through the estuarine process, while silicate flux is unaltered. The authors present some long-term data for nutrient concentrations and the ratios of silicon to nitrogen to phosphorus in the Changjiang Estuary. Silicate level falled in the last two decades, while concentration of nitrate increased. Phosphate concentration had no significant change.展开更多
目的:用Meta分析的方法评价IL-17基因rs763780位点的多态性与胃癌易感性的相关性。方法:计算机检索PubMed、EMBASE、The Cochrane Library、Web of science、万方数据库、中国生物医学文献数据库、中文科技期刊数据库、中国期刊全文数据...目的:用Meta分析的方法评价IL-17基因rs763780位点的多态性与胃癌易感性的相关性。方法:计算机检索PubMed、EMBASE、The Cochrane Library、Web of science、万方数据库、中国生物医学文献数据库、中文科技期刊数据库、中国期刊全文数据库,检索日期自各数据库开始建库至2017年12月,全面检索IL-17基因rs763780位点的多态性与胃癌易感性的病例对照研究文献,采用STATA 12.0统计软件进行Meta分析。结果:最终纳入10篇病例对照研究文献,共计3 892例胃癌患者和4627例健康对照。Meta分析结果显示,IL-17基因rs763780位点多态性在等位基因模型(C vs T:OR=1.90, 95%CI=1.73~2.08)、相加模型(CC vs TT:OR=1.76, 95%CI=1.45~2.14)、共显性模型(CC vs CT:OR=1.26, 95%CI=1.13~1.42)、显性模型(CC vs CT+TT:OR=1.93, 95%CI=1.65~2.26)及与隐性模型(TT vs CT+CC:OR=1.67, 95%CI=1.38~2.03)下均与胃癌的易感性相关。结论:IL-17基因rs763780位点多态性增加了胃癌的发病风险。展开更多
Water quality is critical to ensure that marine resources and the environment are utilized in a sustainable manner. The objective of this study is therefore to investigate the optimum placement of marine environmental...Water quality is critical to ensure that marine resources and the environment are utilized in a sustainable manner. The objective of this study is therefore to investigate the optimum placement of marine environmental monitoring sites to monitor water quality in Shanghai, China. To improve the mapping or estimation accuracy of the areas with different water quality grades, the monitoring sites were fixed in transition bands between areas of different grades rather than in other positions. Following bidirectional optimization method, first, 18 candidate sites were selected by filtering out specific site categories. Second, three of these were, in turn, eliminated because of the rule defined by the changes in the areas of water quality grades and by the standard deviation of the interpolation errors of dissolved inorganic nitrogen(DIN) and phosphate(PO_4-P). Furthermore, indicator kriging was employed to depict the transition bands between different water quality grades whenever new sampling sites were added. The four optimization projects of the newly added sites reveal that, all optimized sites were distributed in the transition bands of different water grades, and at the same time in the areas where the historical sites were sparsely distributed. New sites were also found in the overlap region of different transition bands. Additional sites were especially required in these regions to discriminate the boundaries of different water quality grades. Using the bidirectional optimization method of the monitoring sites, the boundaries of different water quality grades could be determined with a higher precision. As a result, the interpolation errors of DIN and PO_4-P could theoretically decrease.展开更多
基金The National Natural Science Foundation of China (NSFC) under contract No. 30490232Chinese "973" Projectunder contract Nos 2002CB412405 and 2005CB422305
文摘In June 2003 and 2006 concentrations of nutrient were determined in the Changjiang Estuary. The data indicated that phosphate and nitrate did not behave conservatively in the estuary, but silicate behaved conservatively. An important mobilization of phosphate and nitrate was observed from the river up to halfway in the estuary. Both input flux (from river to estuary) and output flux (from estuary to coastal zone) of phosphate, silicate and nitrate were calculated from statistical interpretations of the salinity profiles. There was a large discrepancy between input and output fluxes of phosphate and nitrate. The river fluxes of silicate, phosphate and nitrate (fr) are augmented 5.3%, 28.9% and 36.6% in June 2003 and 1.0%, 62.5%, 31.7% in June 2006 by internal inputs (fi).The phosphate and nitrate fluxes are enhanced through the estuarine process, while silicate flux is unaltered. The authors present some long-term data for nutrient concentrations and the ratios of silicon to nitrogen to phosphorus in the Changjiang Estuary. Silicate level falled in the last two decades, while concentration of nitrate increased. Phosphate concentration had no significant change.
文摘目的:用Meta分析的方法评价IL-17基因rs763780位点的多态性与胃癌易感性的相关性。方法:计算机检索PubMed、EMBASE、The Cochrane Library、Web of science、万方数据库、中国生物医学文献数据库、中文科技期刊数据库、中国期刊全文数据库,检索日期自各数据库开始建库至2017年12月,全面检索IL-17基因rs763780位点的多态性与胃癌易感性的病例对照研究文献,采用STATA 12.0统计软件进行Meta分析。结果:最终纳入10篇病例对照研究文献,共计3 892例胃癌患者和4627例健康对照。Meta分析结果显示,IL-17基因rs763780位点多态性在等位基因模型(C vs T:OR=1.90, 95%CI=1.73~2.08)、相加模型(CC vs TT:OR=1.76, 95%CI=1.45~2.14)、共显性模型(CC vs CT:OR=1.26, 95%CI=1.13~1.42)、显性模型(CC vs CT+TT:OR=1.93, 95%CI=1.65~2.26)及与隐性模型(TT vs CT+CC:OR=1.67, 95%CI=1.38~2.03)下均与胃癌的易感性相关。结论:IL-17基因rs763780位点多态性增加了胃癌的发病风险。
基金supported by the National Natural Science Foundation of China(Nos.41376190,41531179,41421001 and 41601425)the Scientific Research Project of Shanghai Marine Bureau(No.Hu Hai Ke2016-05)the Ocean Public Welfare Scientific Research Project,State Oceanic Administration of the People’s Republic of China(Nos.201505008 and 201305027)
文摘Water quality is critical to ensure that marine resources and the environment are utilized in a sustainable manner. The objective of this study is therefore to investigate the optimum placement of marine environmental monitoring sites to monitor water quality in Shanghai, China. To improve the mapping or estimation accuracy of the areas with different water quality grades, the monitoring sites were fixed in transition bands between areas of different grades rather than in other positions. Following bidirectional optimization method, first, 18 candidate sites were selected by filtering out specific site categories. Second, three of these were, in turn, eliminated because of the rule defined by the changes in the areas of water quality grades and by the standard deviation of the interpolation errors of dissolved inorganic nitrogen(DIN) and phosphate(PO_4-P). Furthermore, indicator kriging was employed to depict the transition bands between different water quality grades whenever new sampling sites were added. The four optimization projects of the newly added sites reveal that, all optimized sites were distributed in the transition bands of different water grades, and at the same time in the areas where the historical sites were sparsely distributed. New sites were also found in the overlap region of different transition bands. Additional sites were especially required in these regions to discriminate the boundaries of different water quality grades. Using the bidirectional optimization method of the monitoring sites, the boundaries of different water quality grades could be determined with a higher precision. As a result, the interpolation errors of DIN and PO_4-P could theoretically decrease.