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生酮饮食的临床应用与研究进展 被引量:13
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作者 刘诗贺 南伟伟 +2 位作者 李晓莲 邾门亮 康继宏 《生理科学进展》 2021年第6期445-450,共6页
生酮饮食(ketogenic diet,KD)是一种低碳水化合物、高脂肪饮食。与传统饮食不同,生酮饮食将脂肪作为机体的主要能量来源。生酮饮食最早用于治疗难治性癫痫,后来在其他疾病,如中枢神经系统疾病、肿瘤和代谢性疾病中得到广泛应用。本文概... 生酮饮食(ketogenic diet,KD)是一种低碳水化合物、高脂肪饮食。与传统饮食不同,生酮饮食将脂肪作为机体的主要能量来源。生酮饮食最早用于治疗难治性癫痫,后来在其他疾病,如中枢神经系统疾病、肿瘤和代谢性疾病中得到广泛应用。本文概述了生酮饮食的起源与发展、分类、临床应用及其作用机制。 展开更多
关键词 生酮饮食 脂肪 酮体 癫痫
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维生素D缺乏对多囊卵巢综合征患者代谢影响的研究进展 被引量:6
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作者 张瑞钰 刘诗贺 +1 位作者 邾门亮 康继宏 《生理科学进展》 2022年第3期213-218,共6页
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄女性最常见的内分泌疾病之一,主要表现为生殖和代谢异常。PCOS患者普遍存在维生素D(vitamin D,VD)缺乏现象。临床研究发现,25-羟基维生素D(25-hydroxyvitamin D,25(OH)D)的水平与P... 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄女性最常见的内分泌疾病之一,主要表现为生殖和代谢异常。PCOS患者普遍存在维生素D(vitamin D,VD)缺乏现象。临床研究发现,25-羟基维生素D(25-hydroxyvitamin D,25(OH)D)的水平与PCOS患者的并发症密切相关,对糖代谢,特别是胰岛素抵抗方面的影响尤为显著。本文概述了维生素D缺乏对PCOS患者代谢影响的可能机制,并简要论述了维生素D补充治疗对患者症状的缓解作用。 展开更多
关键词 维生素D 多囊卵巢综合征 代谢
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甘肃省少数民族地区医学生环境与健康素养现状 被引量:6
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作者 唐莉莉 朱婷 +3 位作者 牛静萍 姜田园 刘氏河 阮烨 《中华疾病控制杂志》 CAS CSCD 北大核心 2020年第4期424-428,472,共6页
目的了解甘肃省少数民族地区医学生环境与健康素养具备情况,为有针对性地开展环境与健康教育,提高该人群的环境与健康素养水平提供科学依据。方法以环境保护部发布的《公民环境与健康素养测评技术指南(试行)》为基础设计问卷。采用分层... 目的了解甘肃省少数民族地区医学生环境与健康素养具备情况,为有针对性地开展环境与健康教育,提高该人群的环境与健康素养水平提供科学依据。方法以环境保护部发布的《公民环境与健康素养测评技术指南(试行)》为基础设计问卷。采用分层整群随机抽样方法,抽取甘肃省少数民族地区1620名在校医学生进行问卷调查。结果甘肃省少数民族地区医学生具备环境与健康素养的比例仅为3.9%。一级分类素养中基本技能素养水平最高(39.0%),基本知识素养水平最低(1.3%);二级分类素养中认知技能素养水平最高(83.9%),科学知识素养水平最低(1.3%)。单因素分析结果显示,不同年级和民族医学生环境与健康素养具备率差异具有统计学意义(均有P<0.05)。多因素分析结果显示,民族、年级、年龄是环境与健康素养水平的影响因素。结论甘肃省少数民族地区医学生的环境与健康素养水平很低,尤其是对环境与健康基本知识方面的了解。学校应有针对性地开展环境与健康教育,提高学生环境健康素养水平。 展开更多
关键词 少数民族 医学生 环境与健康素养 现状分析
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甘肃省合作市乙型肝炎母婴阻断效果分析 被引量:3
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作者 程新香 朱婷 +1 位作者 刘氏河 阮烨 《疾病预防控制通报》 2020年第2期51-53,共3页
目的分析阻断乙型肝炎母婴垂直传播的影响因素,评估乙型肝炎母婴阻断效果。方法选择产检中患有乙型肝炎的孕妇为研究对象,对其新生儿在12 h内接种乙肝疫苗和乙肝免疫球蛋白联合免疫,并完成婴儿期全程乙肝疫苗接种,当婴儿8月龄时开展乙... 目的分析阻断乙型肝炎母婴垂直传播的影响因素,评估乙型肝炎母婴阻断效果。方法选择产检中患有乙型肝炎的孕妇为研究对象,对其新生儿在12 h内接种乙肝疫苗和乙肝免疫球蛋白联合免疫,并完成婴儿期全程乙肝疫苗接种,当婴儿8月龄时开展乙型肝炎血清学检测。结果联合免疫对乙型肝炎母婴传播的总体阻断成功率为78.8%,"大三阳"、"小三阳"、HBsAg(+)+HBeAg(-)和HBsAg(+)+HBeAg(+)的孕妇母婴阻断成功率分别为61.5%,100.0%,84.2%和57.1%,不同感染状况的孕妇母婴阻断成功率差异有统计学意义(χ^2=25.078,P<0.05),乙型肝炎e抗原阳性的母亲阻断成功率低仅60.0%左右;自然分娩阻断成功率为83.3%,剖宫产6人均成功阻断;母乳和人工喂养的婴幼儿阻断成功率分别为80.0%和84.6%,混合喂养3人均成功阻断,不同分娩方式(χ^2=1.171)和喂养方式(χ^2=2.776)的阻断成功率差异无统计学意义(P>0.05)。结论采取科学规范的联合免疫可有效阻断乙型肝炎母婴传播;e抗原阳性的母亲是影响阻断效果的因素,分娩方式和喂养方式对阻断和免疫效果无明显影响。 展开更多
关键词 乙型肝炎 母婴传播 阻断效果
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TURBULENT FLOWS AROUND SAND DUNES IN ALLUVIAL RIVERS 被引量:8
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作者 liu shi-he YIN Shu-ran GUO Wei 《Journal of Hydrodynamics》 SCIE EI CSCD 2010年第1期103-109,共7页
The sand dunes are typical bed forms of natural alluvial rivers. In this article, a vertical 2-D Reynolds stress model is established for the simulation of turbulent flows around sand dunes, and water-sand boundary co... The sand dunes are typical bed forms of natural alluvial rivers. In this article, a vertical 2-D Reynolds stress model is established for the simulation of turbulent flows around sand dunes, and water-sand boundary conditions are set with particular attention. By numerical simulations, the following conclusions can be drawn. (1) The flow resistance in rivers with sand dunes could be divided into the sand-grain resistance and the sand dune resistance, and the sand-grain resistance coefficient mainly depends on Reynolds number, relative sand grain roughness and sand dune steepness. This coefficient in rivers with sand dunes would be larger than that calculated in a flat riverbed, and the steeper the sand dunes, the larger the sand-grain resistance coefficient. (2) The sand dune resistance coefficient mainly depends on the relative sand dune height and sand dune steepness, the steeper the sand dunes, the larger the sand dune resistance coefficient. (3) For the flat riverbed, the turbulent eddy viscosity coefficient and the sediment diffusion coefficient are approximately identical, but for the sand dune riverbed, in the vertical position, where the sediment diffusion coefficient reaches its maximum, it would be higher than the turbulent eddy viscosity coefficient. 展开更多
关键词 sand dune flow resistance sediment diffusion coefficient eddy viscosity
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THEORETICAL ANALYSIS AND NUMERICAL SIMULATION OF TURBULENT FLOW AROUND SAND WAVES AND SAND BARS 被引量:5
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作者 liu shi-he XIONG Xiao-yuan LUO Qiu-shi 《Journal of Hydrodynamics》 SCIE EI CSCD 2009年第2期292-298,共7页
Natural rivers usually possess sand waves and sand bars. In this article, the rapid distortion theory was used to study the turbulent flow over sand waves. The results show that the pre-existing sheafing motion and up... Natural rivers usually possess sand waves and sand bars. In this article, the rapid distortion theory was used to study the turbulent flow over sand waves. The results show that the pre-existing sheafing motion and upstream anisotropy of the turbulence flow would have significant effect on the turbulent structures, and hence the memory effect should be taken into consideration. Furthermore, the 2-D mathematical model was employed to simulate the unsteady flow around the Taiping Sand Bar in the lower reach of the Yangtze River and the time step effect on the unsteady flow simulation with the implicit scheme was discussed at the same time. The results show that the implicit scheme keeps effective until the time step reaches a certain number, and the calculated water levels and velocities are in agreement with the observed data. 展开更多
关键词 sand wave sand-bar rapid distortion theory numerical simulation
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RAIN INTENSITY DISTRIBUTION IN THE SPLASH REGION OF ATOMIZED FLOW 被引量:6
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作者 DUAN Hong-dong liu shi-he +1 位作者 LUO Qiu-shi HUANG Wei 《Journal of Hydrodynamics》 SCIE EI CSCD 2006年第3期362-366,共5页
Atomized flow is an unnatural two-phase flow produced while water discharges in water release structures. This flow might threaten the normal operation of hydraulic and hydroelectric installations owing to the unnatur... Atomized flow is an unnatural two-phase flow produced while water discharges in water release structures. This flow might threaten the normal operation of hydraulic and hydroelectric installations owing to the unnatural and high-density rain as well as the unnatural and dirty mist. The splash region, the region with the highest rain intensity, hence should receive much attention during the design and operation of the hydraulic and hydroelectric installations. In this paper rain intensity distribution in the splash region of the atomized flow is investigated experimentally, and the method of random simulation is used to predict the rain intensity distribution in the splash region. 展开更多
关键词 atomized flow SPLASH rain intensity
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STABILITY AND MIXING CHARACTER FOR BUOYANT JETS IN QUIESCENT SHALLOW WATER 被引量:2
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作者 Ph.D. Candidate: ZENG Yu-hong Huai Wen-xin +6 位作者 Li Wan-ping Tan Guang-ming Li Da-mei liu shi-he Cao Zhi-xian Jin Feng Long Xin-ping 《Journal of Hydrodynamics》 SCIE EI CSCD 2005年第6期776-776,共1页
The near field stahility and mixing characteristics of buoyant jets produced by thermal diffuse in quiescent shallow water are inw.stigated numerically to predict under what combinations of discharge and ambient chara... The near field stahility and mixing characteristics of buoyant jets produced by thermal diffuse in quiescent shallow water are inw.stigated numerically to predict under what combinations of discharge and ambient characteristics the near field will be stable or unstable, Analyses for different discharging types show that the discharge stability is purely dependent on the near-field hehavior of the jets, or the dynam ic interaction of the buoyant jet region, the surface impinge ment region and the internal hydraulic jump region, and is independent of the far-field geometry of the receiving water. The stability criterion is a function of the relative submerged depth, and source densimetrie Froude number. 展开更多
关键词 buoyant jets experimental analysis numcrical analysis STABILITY mixing character
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NUMERICAL SIMULATION OF ATOMIZATION RAINFALL AND THE GENERATED FLOW ON A SLOPE 被引量:2
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作者 liu shi-he TAI Wei +1 位作者 FAN Min LUO Qiu-shi 《Journal of Hydrodynamics》 SCIE EI CSCD 2012年第2期273-279,共7页
This article studies the atomization rainfall and the generated flow on a slope by numerical simulations.The atomization rainfall is simulated by a unified model for splash droplets and a suspended mist,and the distri... This article studies the atomization rainfall and the generated flow on a slope by numerical simulations.The atomization rainfall is simulated by a unified model for splash droplets and a suspended mist,and the distribution of the diameter of splash rain drops is analyzed.The slope runoff generated by the atomization rainfall is simulated by a depth-averaged 2-D model,and the localization of the rainfall intensity in space is specially considered.The simulation results show that:(1) the median rain size of the atomization rainfall increases in the longitudinal direction at first,then monotonously decreases,and the maximum value is taken at the longitudinal position not in consistent with the position where the maximum rain intensity is taken.In the lateral direction the median rain size monotonously decreases,(2) since the atomization rainfall is distributed in a strongly localized area,it takes a longer time for its runoff yield to reach a steady state than that in the natural rainfall,the variation ranges of the water depth and the velocity in the longitudinal and lateral directions are larger than those in the natural rainfall. 展开更多
关键词 atomized flow unified model slope runoff numerical simulation
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SIMULATION OF THE ATOMIZED FLOW BY SLIT TYPE BUCKET ENERGY DISSIPATOR 被引量:2
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作者 liu shi-he DUAN Hong-dong 《Journal of Hydrodynamics》 SCIE EI CSCD 2005年第6期758-763,共6页
Slit type bucket is one kind of flip bucket for energy dissipation generally used in the hydraulic project. In this paper the atomized flow produced behind this energy dis sipator is analyzed, a numerical model for th... Slit type bucket is one kind of flip bucket for energy dissipation generally used in the hydraulic project. In this paper the atomized flow produced behind this energy dis sipator is analyzed, a numerical model for the aerated jet con sidering air entrainment and air resistance force is suggested, and simulation of the rain resulted by the atomized flow is also discussed. Furthermore, the prototype observation data for the atomized flow of Dongjiang Hydropower Station is used to verify the model suggested. 展开更多
关键词 two phase flow atomized flow slit type energy dissipator
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