Atmospheric particulate matter(PM)2.5 is a major carcinogen and is associated with an increased risk of developing various cancers and pulmonary fibrous diseases[1-2].Non-small cell lung cancer(NSCLC)is the major type...Atmospheric particulate matter(PM)2.5 is a major carcinogen and is associated with an increased risk of developing various cancers and pulmonary fibrous diseases[1-2].Non-small cell lung cancer(NSCLC)is the major type of lung cancer with high morbidity and mortality rates.Epidemiological studies report that the incidence of NSCLC,particularly adenocarcinoma,significantly differs with the gender[3].Female patients with NSCLC have unique epidemiologic characteristics,imaging profiles,clinical manifestations,and pathological characteristics[4].展开更多
Organophosphorus pesticides(OPs)are extensively used for their high efficiency,broad spectrum,and low residue.However,the health hazards caused by long-term,low-dose exposure to OPs are easily ignored.Omethoate is a l...Organophosphorus pesticides(OPs)are extensively used for their high efficiency,broad spectrum,and low residue.However,the health hazards caused by long-term,low-dose exposure to OPs are easily ignored.Omethoate is a large class of OPs that is widely used in China.The inhibition of the cholinesterase(ChE)activity is the main toxicity mechanism of OPs,and such an activity is used as a biomarker of exposure to OPs.展开更多
基金supported by the National Key Research and Development Program of China[2017YFC0702700]。
文摘Atmospheric particulate matter(PM)2.5 is a major carcinogen and is associated with an increased risk of developing various cancers and pulmonary fibrous diseases[1-2].Non-small cell lung cancer(NSCLC)is the major type of lung cancer with high morbidity and mortality rates.Epidemiological studies report that the incidence of NSCLC,particularly adenocarcinoma,significantly differs with the gender[3].Female patients with NSCLC have unique epidemiologic characteristics,imaging profiles,clinical manifestations,and pathological characteristics[4].
基金supported by Programs for Science and Technology Development of Zhengzhou[131PPTGG376]the Outstanding Youth Grant of Zhengzhou University[1521329035]
文摘Organophosphorus pesticides(OPs)are extensively used for their high efficiency,broad spectrum,and low residue.However,the health hazards caused by long-term,low-dose exposure to OPs are easily ignored.Omethoate is a large class of OPs that is widely used in China.The inhibition of the cholinesterase(ChE)activity is the main toxicity mechanism of OPs,and such an activity is used as a biomarker of exposure to OPs.
