目的探讨纤维支气管镜检查(fiberoptic bronchoscopy,BFS)行支气管肺泡灌洗术(bronchoalveolar lavage,BAL)在儿童慢性肺炎诊断及治疗中的应用价值。方法选取慢性肺炎患儿136例,其中采用常规治疗的68例患儿设为对照组,在常规治疗基础上...目的探讨纤维支气管镜检查(fiberoptic bronchoscopy,BFS)行支气管肺泡灌洗术(bronchoalveolar lavage,BAL)在儿童慢性肺炎诊断及治疗中的应用价值。方法选取慢性肺炎患儿136例,其中采用常规治疗的68例患儿设为对照组,在常规治疗基础上运用BFS行BAL治疗的68例患儿设为观察组。记录观察组患儿BFS结果与肺泡灌洗液病原检测结果。比较2组临床疗效、症状体征消失时间、动脉血气指标及血清炎症因子水平。监测BFS行BAL可能引起的并发症发生情况。结果观察组68例行BFS的患儿镜下均有不同程度的支气管内膜炎症,其中气道发育异常11例。观察组肺泡灌洗液细菌培养阳性率明显高于痰培养阳性率(P<0.05)。观察组总有效率高于对照组(P<0.05)。观察组发热、咳嗽、肺部湿啰音、哮鸣音消失时间均显著短于对照组(P<0.05)。治疗后,观察组动脉血氧分压(arterial partial pressure of oxygen,PaO2)、酸碱度(power of hydrogen,pH)值明显高于治疗前和对照组,动脉血二氧化碳分压(partial pressure of carbon dioxide in artery,PaCO2)值明显低于治疗前和对照组(P<0.05);对照组治疗前后PaO2、PaCO2、pH值差异无统计学意义(P>0.05)。治疗后,2组血清白细胞介素6(interleukin-6,IL-6)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)浓度明显低于治疗前,且观察组IL-6、TNF-α水平低于对照组(P<0.05)。观察组患儿BFS行BAL治疗过程中出现经皮血氧饱和度降低4例,支气管黏膜出血6例,但均较轻微,经对症处理后缓解。结论应用BFS行BAL治疗对儿童慢性肺炎的病因诊断、病原体检测及治疗均具有较高的临床应用价值,患儿耐受性较好。展开更多
目的探讨静脉窦支架置入术对合并静脉窦狭窄的特发性颅内高压(idiopathic intracranial hypertension,IIH)的治疗作用。方法回顾性分析2009年7月-2019年1月在解放军总医院第一医学中心确诊并行静脉窦狭窄支架置入术的IIH患者的临床资料...目的探讨静脉窦支架置入术对合并静脉窦狭窄的特发性颅内高压(idiopathic intracranial hypertension,IIH)的治疗作用。方法回顾性分析2009年7月-2019年1月在解放军总医院第一医学中心确诊并行静脉窦狭窄支架置入术的IIH患者的临床资料。术前清醒状态和术后即刻测静脉窦狭窄远近端压力差。术后1周复查腰椎穿刺测颅内压,随访术后1年临床症状改善情况。术后6~12个月行DSA检查,评估静脉窦支架置入术对合并静脉窦狭窄的IIH的治疗作用。结果共纳入97例患者,其中75例(77.3%)女性,22例(22.7%)男性,中位年龄35(15~57)岁。术前存在视力障碍74例(76.2%),头痛54例(55.7%)。97例患者行静脉窦狭窄支架置入治疗,其中93例行单侧静脉窦狭窄支架治疗,4例行双侧静脉窦狭窄支架治疗。支架置入术中未发生并发症。支架置入术后静脉窦狭窄远近端压力差减小(18.1±7.1 vs 1.1±1.0 mm Hg,P<0.001),腰穿检查脑脊液压力显著下降(297.0±44.8 vs 215.0±41.2 mm H2O,P=0.004)。76例患者完成了1年临床随访,其中64例视力障碍患者中56例(87.5%)明显好转,43例头痛患者中40例(93.0%)头痛减轻或消失。DSA检查随访62例,3例(4.8%)出现支架内再狭窄,2例(3.2%)出现硬脑膜动静脉瘘。结论静脉窦支架置入术是治疗合并静脉窦狭窄的IIH的一种安全、有效的治疗方式。展开更多
We conduct a comprehensive analysis of the current situation of security system for implementation of China's land consolidation planning. The prominent problems in the process of implementing safeguard measures f...We conduct a comprehensive analysis of the current situation of security system for implementation of China's land consolidation planning. The prominent problems in the process of implementing safeguard measures for planning are summarized as follows: the guiding ideology for planning formulation is imperfect; the legal basis is weak, and administrative means are not sound; the economic security mechanism is not brought into full play, and the social security measures still need to be further deepened; the technical safeguard measures are short. From laws and regulations, administrative management, economic security, social supervision, technology management and other aspects, we establish the scientific security system for implementation of land consolidation planning; put forth the recommendations for guaranteeing the implementation of planning in China.展开更多
[ Objective] To investigate the optimal culture system for in vitro fertilization （IVF） of oocyte in bovine. [ Method] The IVF of mature bovine oocytes was conducted and the fertilized eggs were cultured in vitro wi...[ Objective] To investigate the optimal culture system for in vitro fertilization （IVF） of oocyte in bovine. [ Method] The IVF of mature bovine oocytes was conducted and the fertilized eggs were cultured in vitro with different culture systems. In the traditional culture system, the TALP medium and BO medium were used as fertilization medium, respectively; and M-199 medium supplemented with 5% FCS was used as fertilized egg culture medium. In the transitional culture system, the TALP medium and BO medium were used as fertilization medium; 60% TALP and 40% M-199 supplemented with 5% FCS and 60% BO and 40% M-199 supplemented with 5% FCS were used as fertilized egg culture medium, respectively. The effects of different culture systems on fertilization rate and cleavage rate were observed. E Result] In the transitional culture system （with TALP medium as fertilization medium and with 60% TALP and 40% M-199 supplemented with 5% FCS as fertilized egg culture medium）, the fertilization rate and cleavage rate were increased to 77.8% and 55.6%, respectively. [ Conclusion] The transitional culture system （with TALP medium as fertilization medium and with 60% TALP and 40% M-199 supplemented with 5% FCS as fertilized egg culture medium） is the optimal culture system for IVF of bovine oocyte.展开更多
文摘目的探讨纤维支气管镜检查(fiberoptic bronchoscopy,BFS)行支气管肺泡灌洗术(bronchoalveolar lavage,BAL)在儿童慢性肺炎诊断及治疗中的应用价值。方法选取慢性肺炎患儿136例,其中采用常规治疗的68例患儿设为对照组,在常规治疗基础上运用BFS行BAL治疗的68例患儿设为观察组。记录观察组患儿BFS结果与肺泡灌洗液病原检测结果。比较2组临床疗效、症状体征消失时间、动脉血气指标及血清炎症因子水平。监测BFS行BAL可能引起的并发症发生情况。结果观察组68例行BFS的患儿镜下均有不同程度的支气管内膜炎症,其中气道发育异常11例。观察组肺泡灌洗液细菌培养阳性率明显高于痰培养阳性率(P<0.05)。观察组总有效率高于对照组(P<0.05)。观察组发热、咳嗽、肺部湿啰音、哮鸣音消失时间均显著短于对照组(P<0.05)。治疗后,观察组动脉血氧分压(arterial partial pressure of oxygen,PaO2)、酸碱度(power of hydrogen,pH)值明显高于治疗前和对照组,动脉血二氧化碳分压(partial pressure of carbon dioxide in artery,PaCO2)值明显低于治疗前和对照组(P<0.05);对照组治疗前后PaO2、PaCO2、pH值差异无统计学意义(P>0.05)。治疗后,2组血清白细胞介素6(interleukin-6,IL-6)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)浓度明显低于治疗前,且观察组IL-6、TNF-α水平低于对照组(P<0.05)。观察组患儿BFS行BAL治疗过程中出现经皮血氧饱和度降低4例,支气管黏膜出血6例,但均较轻微,经对症处理后缓解。结论应用BFS行BAL治疗对儿童慢性肺炎的病因诊断、病原体检测及治疗均具有较高的临床应用价值,患儿耐受性较好。
文摘目的探讨静脉窦支架置入术对合并静脉窦狭窄的特发性颅内高压(idiopathic intracranial hypertension,IIH)的治疗作用。方法回顾性分析2009年7月-2019年1月在解放军总医院第一医学中心确诊并行静脉窦狭窄支架置入术的IIH患者的临床资料。术前清醒状态和术后即刻测静脉窦狭窄远近端压力差。术后1周复查腰椎穿刺测颅内压,随访术后1年临床症状改善情况。术后6~12个月行DSA检查,评估静脉窦支架置入术对合并静脉窦狭窄的IIH的治疗作用。结果共纳入97例患者,其中75例(77.3%)女性,22例(22.7%)男性,中位年龄35(15~57)岁。术前存在视力障碍74例(76.2%),头痛54例(55.7%)。97例患者行静脉窦狭窄支架置入治疗,其中93例行单侧静脉窦狭窄支架治疗,4例行双侧静脉窦狭窄支架治疗。支架置入术中未发生并发症。支架置入术后静脉窦狭窄远近端压力差减小(18.1±7.1 vs 1.1±1.0 mm Hg,P<0.001),腰穿检查脑脊液压力显著下降(297.0±44.8 vs 215.0±41.2 mm H2O,P=0.004)。76例患者完成了1年临床随访,其中64例视力障碍患者中56例(87.5%)明显好转,43例头痛患者中40例(93.0%)头痛减轻或消失。DSA检查随访62例,3例(4.8%)出现支架内再狭窄,2例(3.2%)出现硬脑膜动静脉瘘。结论静脉窦支架置入术是治疗合并静脉窦狭窄的IIH的一种安全、有效的治疗方式。
文摘We conduct a comprehensive analysis of the current situation of security system for implementation of China's land consolidation planning. The prominent problems in the process of implementing safeguard measures for planning are summarized as follows: the guiding ideology for planning formulation is imperfect; the legal basis is weak, and administrative means are not sound; the economic security mechanism is not brought into full play, and the social security measures still need to be further deepened; the technical safeguard measures are short. From laws and regulations, administrative management, economic security, social supervision, technology management and other aspects, we establish the scientific security system for implementation of land consolidation planning; put forth the recommendations for guaranteeing the implementation of planning in China.
基金supported by the Scientific Research & Development Fund of Tianjin Agricultural University
文摘[ Objective] To investigate the optimal culture system for in vitro fertilization （IVF） of oocyte in bovine. [ Method] The IVF of mature bovine oocytes was conducted and the fertilized eggs were cultured in vitro with different culture systems. In the traditional culture system, the TALP medium and BO medium were used as fertilization medium, respectively; and M-199 medium supplemented with 5% FCS was used as fertilized egg culture medium. In the transitional culture system, the TALP medium and BO medium were used as fertilization medium; 60% TALP and 40% M-199 supplemented with 5% FCS and 60% BO and 40% M-199 supplemented with 5% FCS were used as fertilized egg culture medium, respectively. The effects of different culture systems on fertilization rate and cleavage rate were observed. E Result] In the transitional culture system （with TALP medium as fertilization medium and with 60% TALP and 40% M-199 supplemented with 5% FCS as fertilized egg culture medium）, the fertilization rate and cleavage rate were increased to 77.8% and 55.6%, respectively. [ Conclusion] The transitional culture system （with TALP medium as fertilization medium and with 60% TALP and 40% M-199 supplemented with 5% FCS as fertilized egg culture medium） is the optimal culture system for IVF of bovine oocyte.
