The Nianzi granite unit,which includes the Nianzi,Xiaolianghou and Xiawopu granitic intrusions,is a significant component of the northern part of the North China Craton(NCC)and is situated in the Yanshan fold and thru...The Nianzi granite unit,which includes the Nianzi,Xiaolianghou and Xiawopu granitic intrusions,is a significant component of the northern part of the North China Craton(NCC)and is situated in the Yanshan fold and thrust belt(YFTB).However,there is still debate regarding the tectonic evolutionary history of the YFTB during the late Permian to Triassic period,specifically regarding the timing of subduction and collision between the NCC and the Paleo-Asian Ocean.The Nianzi granite unit exhibits unique petrological,geochronological and geochemical signatures that shed light on the tectonic evolutionary history of the YFTB.This study presents detailed petrology,whole-rock geochemistry,together with Sr-Nd isotopic,zircon U-Pb dating and Lu-Hf isotopic data of the granites within the Nianzi granite unit.Our findings demonstrate that the granites primarily consist of subhedral K-feldspar,plagioclase,quartz,minor biotite and hornblende,with accessory titanite,apatite,magnetite and zircon.Zircon U-Pb dating indicates that the Xiaolianghou granite was emplaced at 247.5±0.62 Ma.Additionally,the adakitic characteristics of the Nianzi,Xiawopu and Xiaolianghou granitic intrusions,such as high Sr and Ba contents and high ratios of Sr/Y and(La/Yb)N,combined with negative Sr-Nd and Lu-Hf isotopes(87Sr/86Sr)i=0.705681–0.7057433,εNd(t)=−21.98 to−20.97,zirconεHf(t)=−20.26 to−9.92,as well as the I-type granite features of high SiO_(2),Na_(2)O and K_(2)O/Na_(2)O ratios,enriched Rb,K,Sr and Ba,along with depleted Th,U,Nb,Ta,P and Ti,suggest that the Nianzi granitic unit was mainly derived from the partial melting of a thickened lower crust containing hydrous,calc-alkaline to high-K calc-alkaline,mafic to intermediate metamorphic rocks.In light of these parameters,we further integrate our data with previous studies and conclude that the Nianzi granitic unit was generated in a post-collisional extensional environment during the Early Triassic.展开更多
目的研究女性骨密度峰值阶段腰椎骨密度与体脂分布的相关性,探讨青年女性瘦身与老年骨质疏松症发生的关系。方法纳入一组25~35岁的女性志愿者,采集每位志愿者的一般信息(身高、体重、腰围、臀围),计算体质量指数(body mass index,BMI)...目的研究女性骨密度峰值阶段腰椎骨密度与体脂分布的相关性,探讨青年女性瘦身与老年骨质疏松症发生的关系。方法纳入一组25~35岁的女性志愿者,采集每位志愿者的一般信息(身高、体重、腰围、臀围),计算体质量指数(body mass index,BMI)和腰臀比(waist-hip ratio,WHR)。依据BMI将其分为两组,瘦型(BMI<21.4)和胖型(BMI≥21.4)。利用Midways pro定量CT(QCT)分析系统,测量脐水平腹内脂肪面积(visceral fat area,VFA)、腹壁脂肪面积(subcutaneous fat area,SFA)、腰椎2~4的骨密度(bone mineral density,BMD),计算腹脂比(VF/SF)及腰椎平均BMD(vBMD)。两组间体脂参数、vBMD的差异比较采用独立样本 t 检验,vBMD与体脂参数的相关性采用 Pearson 相关性检验。结果纳入共计95名志愿者,其中瘦型43名,胖型52名。两组间VFA、SFA比较差异具有统计学意义, P 值分别为0.01、0.003;两组间腰臀比、VF/SF、vBMD比较差异没有统计学意义;青年女性腰椎vBMD与VF/SF呈显著性相关( r =0.381, P =0.034)。结论女性腰椎峰值骨密度与BMI、腰围、臀围、VFA、SFA不具有相关性,与腹脂比(VF/SF)显著相关。青年女性科学瘦身不会降低机体骨密度储备。展开更多
传统惯导/卫导组合导航在多元复杂环境下易受干扰,从而导致观测量异常影响导航性能。以无人驾驶车辆为研究对象,展开提升组合导航系统导航精度的研究。采用深度高斯过程(deep Gaussian process,DGP)辅助估计位置的方法减小组合导航误差...传统惯导/卫导组合导航在多元复杂环境下易受干扰,从而导致观测量异常影响导航性能。以无人驾驶车辆为研究对象,展开提升组合导航系统导航精度的研究。采用深度高斯过程(deep Gaussian process,DGP)辅助估计位置的方法减小组合导航误差,提高定位性能。基于DGP的辅助导航方法不仅可以预测无人驾驶车辆的标称轨迹,同时可以预测各时刻位置可信区间的概率分布,为基于深度学习模型的数据融合预测方法提供了严格的理论解释性。真实历史数据下的多重对比实验表明,该算法较传统深度神经网络算法具有更高的精度和可靠性。基于DGP的辅助导航方式能有效提高全球卫星定位系统信号失锁时的导航模型性能,实验表明相对于纯惯性导航系统(integral navigation system,INS)解算和长短期记忆(long and short term memory,LSTM)进行导航信号补偿定位精度分别提高了97.32%和52.13%。展开更多
CD68因子是一种在外周血单核细胞和巨噬细胞中高度表达的蛋白质,是单核巨噬细胞主要抗原之一,又称CD68抗原、GP110、巨噬细胞黏蛋白(Macrosialin)、清道夫受体D1(Scavenger Receptor Class D,Member 1,SCARD1)和LAMP4,是血液系统的黏蛋...CD68因子是一种在外周血单核细胞和巨噬细胞中高度表达的蛋白质,是单核巨噬细胞主要抗原之一,又称CD68抗原、GP110、巨噬细胞黏蛋白(Macrosialin)、清道夫受体D1(Scavenger Receptor Class D,Member 1,SCARD1)和LAMP4,是血液系统的黏蛋白(mucin)样分子家族、溶酶体/核内体相关膜糖蛋白LAMP家族和清道夫受体家族的成员之一。肿瘤微环境中的巨噬细胞称为肿瘤相关巨噬细胞(TAMs),参与肿瘤增殖、血管生成、浸润、转移及化疗抵抗。在血液系统恶性疾病中,巨噬细胞广泛浸润到淋巴瘤、骨髓瘤、白血病等恶性细胞累及的组织中,被恶性微环境异常活化,获得了特异的活化表型,并参与疾病进展。在白血病中其名称引申为白血病相关巨噬细胞、急性白血病相关巨噬细胞或者“保姆样细胞”。本文综述了白血病中CD68因子的研究进展。展开更多
Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide h...Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide hazard zonation and risk assessment. The 1992 Anbalagan and Singh method of landslide hazard zonation （LHZ） was modified and used in this area. In this way, an Associative Analysis Method was used in representative areas to get a measure for controlling factors （slope gradient, relative relief, vegetation, geology, discontinuity development, weak layer thickness and ground water）. For the membership degree of factor to slope failure, the middle range of limited values was used to calculate LHZ. Based on an estimation of the potential damage from slope failure, a reasonable risk assessment map was obtained using the relationship of potential damage and probable hazard to aid future planning and prediction and to avert loss of life.展开更多
基金funded by the National Natural Science Foundation of China(41872232)the Beijing Geological Survey Project(PXM 2016-158203-000008,PXM 2018-158203-000014)the Beijing Innovation Studio(Urban Geology,Active Structure,and Monitoring).
文摘The Nianzi granite unit,which includes the Nianzi,Xiaolianghou and Xiawopu granitic intrusions,is a significant component of the northern part of the North China Craton(NCC)and is situated in the Yanshan fold and thrust belt(YFTB).However,there is still debate regarding the tectonic evolutionary history of the YFTB during the late Permian to Triassic period,specifically regarding the timing of subduction and collision between the NCC and the Paleo-Asian Ocean.The Nianzi granite unit exhibits unique petrological,geochronological and geochemical signatures that shed light on the tectonic evolutionary history of the YFTB.This study presents detailed petrology,whole-rock geochemistry,together with Sr-Nd isotopic,zircon U-Pb dating and Lu-Hf isotopic data of the granites within the Nianzi granite unit.Our findings demonstrate that the granites primarily consist of subhedral K-feldspar,plagioclase,quartz,minor biotite and hornblende,with accessory titanite,apatite,magnetite and zircon.Zircon U-Pb dating indicates that the Xiaolianghou granite was emplaced at 247.5±0.62 Ma.Additionally,the adakitic characteristics of the Nianzi,Xiawopu and Xiaolianghou granitic intrusions,such as high Sr and Ba contents and high ratios of Sr/Y and(La/Yb)N,combined with negative Sr-Nd and Lu-Hf isotopes(87Sr/86Sr)i=0.705681–0.7057433,εNd(t)=−21.98 to−20.97,zirconεHf(t)=−20.26 to−9.92,as well as the I-type granite features of high SiO_(2),Na_(2)O and K_(2)O/Na_(2)O ratios,enriched Rb,K,Sr and Ba,along with depleted Th,U,Nb,Ta,P and Ti,suggest that the Nianzi granitic unit was mainly derived from the partial melting of a thickened lower crust containing hydrous,calc-alkaline to high-K calc-alkaline,mafic to intermediate metamorphic rocks.In light of these parameters,we further integrate our data with previous studies and conclude that the Nianzi granitic unit was generated in a post-collisional extensional environment during the Early Triassic.
文摘目的研究女性骨密度峰值阶段腰椎骨密度与体脂分布的相关性,探讨青年女性瘦身与老年骨质疏松症发生的关系。方法纳入一组25~35岁的女性志愿者,采集每位志愿者的一般信息(身高、体重、腰围、臀围),计算体质量指数(body mass index,BMI)和腰臀比(waist-hip ratio,WHR)。依据BMI将其分为两组,瘦型(BMI<21.4)和胖型(BMI≥21.4)。利用Midways pro定量CT(QCT)分析系统,测量脐水平腹内脂肪面积(visceral fat area,VFA)、腹壁脂肪面积(subcutaneous fat area,SFA)、腰椎2~4的骨密度(bone mineral density,BMD),计算腹脂比(VF/SF)及腰椎平均BMD(vBMD)。两组间体脂参数、vBMD的差异比较采用独立样本 t 检验,vBMD与体脂参数的相关性采用 Pearson 相关性检验。结果纳入共计95名志愿者,其中瘦型43名,胖型52名。两组间VFA、SFA比较差异具有统计学意义, P 值分别为0.01、0.003;两组间腰臀比、VF/SF、vBMD比较差异没有统计学意义;青年女性腰椎vBMD与VF/SF呈显著性相关( r =0.381, P =0.034)。结论女性腰椎峰值骨密度与BMI、腰围、臀围、VFA、SFA不具有相关性,与腹脂比(VF/SF)显著相关。青年女性科学瘦身不会降低机体骨密度储备。
文摘传统惯导/卫导组合导航在多元复杂环境下易受干扰,从而导致观测量异常影响导航性能。以无人驾驶车辆为研究对象,展开提升组合导航系统导航精度的研究。采用深度高斯过程(deep Gaussian process,DGP)辅助估计位置的方法减小组合导航误差,提高定位性能。基于DGP的辅助导航方法不仅可以预测无人驾驶车辆的标称轨迹,同时可以预测各时刻位置可信区间的概率分布,为基于深度学习模型的数据融合预测方法提供了严格的理论解释性。真实历史数据下的多重对比实验表明,该算法较传统深度神经网络算法具有更高的精度和可靠性。基于DGP的辅助导航方式能有效提高全球卫星定位系统信号失锁时的导航模型性能,实验表明相对于纯惯性导航系统(integral navigation system,INS)解算和长短期记忆(long and short term memory,LSTM)进行导航信号补偿定位精度分别提高了97.32%和52.13%。
文摘CD68因子是一种在外周血单核细胞和巨噬细胞中高度表达的蛋白质,是单核巨噬细胞主要抗原之一,又称CD68抗原、GP110、巨噬细胞黏蛋白(Macrosialin)、清道夫受体D1(Scavenger Receptor Class D,Member 1,SCARD1)和LAMP4,是血液系统的黏蛋白(mucin)样分子家族、溶酶体/核内体相关膜糖蛋白LAMP家族和清道夫受体家族的成员之一。肿瘤微环境中的巨噬细胞称为肿瘤相关巨噬细胞(TAMs),参与肿瘤增殖、血管生成、浸润、转移及化疗抵抗。在血液系统恶性疾病中,巨噬细胞广泛浸润到淋巴瘤、骨髓瘤、白血病等恶性细胞累及的组织中,被恶性微环境异常活化,获得了特异的活化表型,并参与疾病进展。在白血病中其名称引申为白血病相关巨噬细胞、急性白血病相关巨噬细胞或者“保姆样细胞”。本文综述了白血病中CD68因子的研究进展。
文摘Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide hazard zonation and risk assessment. The 1992 Anbalagan and Singh method of landslide hazard zonation （LHZ） was modified and used in this area. In this way, an Associative Analysis Method was used in representative areas to get a measure for controlling factors （slope gradient, relative relief, vegetation, geology, discontinuity development, weak layer thickness and ground water）. For the membership degree of factor to slope failure, the middle range of limited values was used to calculate LHZ. Based on an estimation of the potential damage from slope failure, a reasonable risk assessment map was obtained using the relationship of potential damage and probable hazard to aid future planning and prediction and to avert loss of life.
