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p53-ZDHHC1-IFITM3棕榈酰化修饰通路抑制日本脑炎病毒复制的作用研究 被引量:3
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作者 WANG XIN WU ZHUAN-CHANG liyu-ming 《中国预防兽医学报》 CAS CSCD 北大核心 2020年第12期1309-1309,共1页
日本脑炎病毒(Japanese encephalitis virus,JEV)属于黄病毒科黄病毒属,能够引起人的中枢神经系统损伤和猪的繁殖障碍等疾病。p53是最著名的肿瘤抑制因子之一,近年研究发现p53还可参与固有免疫与病毒复制调控,本研究室前期研究发现p53... 日本脑炎病毒(Japanese encephalitis virus,JEV)属于黄病毒科黄病毒属,能够引起人的中枢神经系统损伤和猪的繁殖障碍等疾病。p53是最著名的肿瘤抑制因子之一,近年研究发现p53还可参与固有免疫与病毒复制调控,本研究室前期研究发现p53能抑制JEV的复制,但具体机制尚不清楚。 展开更多
关键词 日本脑炎病毒 黄病毒科 繁殖障碍 JEV 中枢神经系统损伤 黄病毒属 棕榈酰化修饰 固有免疫
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某综合医院SARS暴发与控制 被引量:1
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作者 WANGShi-xin liyu-ming +8 位作者 CHANGAi-hua GAOXiu-xia WEIMao-ti YANGZhen ZHANGJian-peng ZHANGZhi-lun SHENPeng TIANWen-feng JIAGang 《武警医学院学报》 CAS 2003年第6期409-417,F002,共10页
Objective:To investigate the SARS epidemic and the control effectiveness in a general hospital. Methods:Clinical and suspected cases of SARS were queried in the hospital, the emerging of the disease was described and ... Objective:To investigate the SARS epidemic and the control effectiveness in a general hospital. Methods:Clinical and suspected cases of SARS were queried in the hospital, the emerging of the disease was described and the effectiveness of control measures were analyzed according to the rules and protective materials used during the epidemic. Results:The outbreak started with a patient from Beijing on 15 April. The disease spread quickly among the healthcare workers and the cohabit patients in the hospital which the first cases were admitted. By 17 May, 112 probable (clinical cases) and suspected cases had been reported with 14 deaths. 89 cases in the hospital were surely sourced from the index SARS patient whose admission for the sake of coronary heart disease caused the SARS outbreak. With the stringent control measures and the endeavors of the hospital staff, the epidemic was controlled successfully in a short period. From May 17 to now, no new cases occurred. Conclusion:Though with high infectivity, SARS can also be controlled with proper strategy and methods. 展开更多
关键词 流行病学 SARS 非典型肺炎 医院感染
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