婴儿猝死综合征(sudden infant death syndrome,SIDS)是婴儿死亡的重要原因。2013年HRS/EHRA/APHRS专家共识将不明原因的婴儿猝死纳入遗传性心律失常范围。约12%的SIDS由长QT综合征导致,与SIDS相关的离子通道病还包括Brugada综合征、儿...婴儿猝死综合征(sudden infant death syndrome,SIDS)是婴儿死亡的重要原因。2013年HRS/EHRA/APHRS专家共识将不明原因的婴儿猝死纳入遗传性心律失常范围。约12%的SIDS由长QT综合征导致,与SIDS相关的离子通道病还包括Brugada综合征、儿茶酚胺敏感性多形性室速、短QT综合征。此外,研究发现早期复极常伴随长QT综合征、Brugada综合征、短QT综合征疾病出现,并且进一步增加心律失常事件的风险。心电图描记术简单、无创、廉价、易行,对遗传性心律失常诱发的SIDS有重要的筛查、预警和诊断意义。展开更多
Background The ankle brachial index （ABI） is a simple, inexpensive, noninvasive tool that correlates well with angiographic disease severity and functional symptoms. The aim of this study was to identify the manifes...Background The ankle brachial index （ABI） is a simple, inexpensive, noninvasive tool that correlates well with angiographic disease severity and functional symptoms. The aim of this study was to identify the manifestation of lower extremity atherosclerotic lesions in patients with high ABI by retrospective clinical study.Methods A cohort of 184 diabetic patients, （63±14） years old, 144 males, who underwent simultaneously ABI testing and low extremity arterial duplex ultrasound within one week, were enrolled randomly into this study. According to the ABI value, they were divided into three groups： the high, normal and low ABI groups. The severity and location of atherosclerotic lesions in the lower extremity were determined based on the results of low extremity artery duplex ultrasound. The chi-square test was used to compare the atherosclerosis severity grade and lesion location across the three groups.Results The prevalence of low extremity artery occlusion was significantly lower in the high ABI group than in the low ABI group （3.3% vs. 63.5%, P〈0.01）, and the main atherosclerotic lesions were diffuse dot-like hyperechogenicity spots or small plaques （86.7%）. In addition, the atherosclerotic lesions were mostly found in the distal segment of the lower extremity in patients with high ABI （46.3%）.Conclusion A high ABI may be an integrative marker for intimal and medial calcification, which has a high positive predictive value for artery calcification.展开更多
文摘婴儿猝死综合征(sudden infant death syndrome,SIDS)是婴儿死亡的重要原因。2013年HRS/EHRA/APHRS专家共识将不明原因的婴儿猝死纳入遗传性心律失常范围。约12%的SIDS由长QT综合征导致,与SIDS相关的离子通道病还包括Brugada综合征、儿茶酚胺敏感性多形性室速、短QT综合征。此外,研究发现早期复极常伴随长QT综合征、Brugada综合征、短QT综合征疾病出现,并且进一步增加心律失常事件的风险。心电图描记术简单、无创、廉价、易行,对遗传性心律失常诱发的SIDS有重要的筛查、预警和诊断意义。
文摘Background The ankle brachial index （ABI） is a simple, inexpensive, noninvasive tool that correlates well with angiographic disease severity and functional symptoms. The aim of this study was to identify the manifestation of lower extremity atherosclerotic lesions in patients with high ABI by retrospective clinical study.Methods A cohort of 184 diabetic patients, （63±14） years old, 144 males, who underwent simultaneously ABI testing and low extremity arterial duplex ultrasound within one week, were enrolled randomly into this study. According to the ABI value, they were divided into three groups： the high, normal and low ABI groups. The severity and location of atherosclerotic lesions in the lower extremity were determined based on the results of low extremity artery duplex ultrasound. The chi-square test was used to compare the atherosclerosis severity grade and lesion location across the three groups.Results The prevalence of low extremity artery occlusion was significantly lower in the high ABI group than in the low ABI group （3.3% vs. 63.5%, P〈0.01）, and the main atherosclerotic lesions were diffuse dot-like hyperechogenicity spots or small plaques （86.7%）. In addition, the atherosclerotic lesions were mostly found in the distal segment of the lower extremity in patients with high ABI （46.3%）.Conclusion A high ABI may be an integrative marker for intimal and medial calcification, which has a high positive predictive value for artery calcification.
