Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 ye...Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 years from seven provinces in China during September 2014.Anthropometric indices and blood pressure were measured at recruitment,and blood samples were collected for determining fasting plasma glucose and lipid profile.Receiver operating characteristic(ROC)analyses were used to assess the predictive performance of anthropometric indices,including body mass index(BMI)percentile,waist circumference percentile,waist-height ratio,and waist-hip ratio.Results Overall,the four anthropometric indices showed good accuracy for predicting Met S with areas under ROC curves(AUCs)ranging from 0.86 to 0.94;similar AUCs ranging from 0.73 to 0.99 were observed for participants with normal weight.The performance of all four indices was poor in overweight and obese participants,with AUCs ranging from 0.66 to 0.77 and from 0.60 to 0.67,respectively.Waist circumference showed relatively better performance in all the subgroup analyses.Conclusions We suggest using anthropometric indices with the cutoff values presented here for predicting Met S in the overall and normal-weight adolescent population,but not in the overweight and obese adolescent population where more specific screening tests are required.展开更多
基金supported by the Medical Research Council,the Research Special Fund for Public Welfare of Health[Grant No.201202010]Hunan Provincial Natural Science Foundation of China[Grant No.2018JJ2553]。
文摘Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 years from seven provinces in China during September 2014.Anthropometric indices and blood pressure were measured at recruitment,and blood samples were collected for determining fasting plasma glucose and lipid profile.Receiver operating characteristic(ROC)analyses were used to assess the predictive performance of anthropometric indices,including body mass index(BMI)percentile,waist circumference percentile,waist-height ratio,and waist-hip ratio.Results Overall,the four anthropometric indices showed good accuracy for predicting Met S with areas under ROC curves(AUCs)ranging from 0.86 to 0.94;similar AUCs ranging from 0.73 to 0.99 were observed for participants with normal weight.The performance of all four indices was poor in overweight and obese participants,with AUCs ranging from 0.66 to 0.77 and from 0.60 to 0.67,respectively.Waist circumference showed relatively better performance in all the subgroup analyses.Conclusions We suggest using anthropometric indices with the cutoff values presented here for predicting Met S in the overall and normal-weight adolescent population,but not in the overweight and obese adolescent population where more specific screening tests are required.