Acute pain is a warning protective sensation for any impending harm.However,chronic pain syndromes are often resistant diseases that may consume large amount of health care costs.It has been suggested by recent studie...Acute pain is a warning protective sensation for any impending harm.However,chronic pain syndromes are often resistant diseases that may consume large amount of health care costs.It has been suggested by recent studies that pain perception may be formed in central neural networks via large-scale coding processes,which involves sensory,affective,and cognitive dimensions.Many central areas are involved in these processes,including structures from the spinal cord,the brain stem,the limbic system,to the cortices.Thus,chronic painful diseases may be the result of some abnormal coding within this network.A thorough investigation of coding mechanism of pain within the central neuromatrix will bring us great insight into the mechanisms responsible for the development of chronic pain,hence leading to novel therapeutic interventions for pain management.展开更多
基金the National Natural Science Foundation of China(No.30570577,30770688,30700223)the 100 Talents Programme of Chinese Academy of Sciences,the National Hi-Tech Development Program of China(No.2006AA02Z431)+1 种基金a grant from Beijing Natural Science Foundation(No.5082008)to FLa Young Scientist grant(No.07CX051005)from ChineseAcademy of Science to JYW
文摘Acute pain is a warning protective sensation for any impending harm.However,chronic pain syndromes are often resistant diseases that may consume large amount of health care costs.It has been suggested by recent studies that pain perception may be formed in central neural networks via large-scale coding processes,which involves sensory,affective,and cognitive dimensions.Many central areas are involved in these processes,including structures from the spinal cord,the brain stem,the limbic system,to the cortices.Thus,chronic painful diseases may be the result of some abnormal coding within this network.A thorough investigation of coding mechanism of pain within the central neuromatrix will bring us great insight into the mechanisms responsible for the development of chronic pain,hence leading to novel therapeutic interventions for pain management.
