Background: Our aim was to assess the safety and efficacy of primary and secon dary implantation of a black diaphragm aniridia intraocular lens (IOL) in patien ts that lacked a complete iris diaphragm. Methods: This w...Background: Our aim was to assess the safety and efficacy of primary and secon dary implantation of a black diaphragm aniridia intraocular lens (IOL) in patien ts that lacked a complete iris diaphragm. Methods: This was a retrospective non -comparative study of six eyes in five patients with iris defects. The causes o f such defects included congenital aniridia, traumatic aniridia, and oculocutane ous albinism. Three eyes underwent primary implantations of a black diaphragm IO L, and three eyes were given secondary implantations. The visual acuity, subject ive severity of glare, postoperative anatomical outcome and any intraoperative o r postoperative complications were reviewed. Results: The mean follow-up period was 20.6 months (range 3-29 months. All patients showed stable or improvement in best-corrected visual acuity postoperatively. Glare and photophobia had impr oved subjectively in all patients after implantation of the black diaphragm IOL. Intraoperative complication included one case of hyphaema and iris damage durin g insertion of the IOL. Postoperative complications included intraocular inflamm ation with choroidal detachment, secondary glaucoma, and persistent epithelial d efect after surgery. None of the patients developed decentration of IOL after su rgery. Conclusion: The black diaphragm aniridia IOL is useful in the management of the condition in patients with iris deficiency including oculocutaneous albin ism. Intraoperative and postoperative complications are not uncommon, and patients should be monitored carefully in the perioperative period.展开更多
Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.De...Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.Design Interventional con secutive case series.Methods Patients scheduled for ERM s urgery were re-cruited prospectively.Pars plana v itrectomy,removal of ERM,and ILM peeling with indocyanin e green(ICG)staining were performed in all patie nts.Epiretinal mem-brane and ILM specimens were sent for histologic exam-ination.The amount of ERM present in ILM specimens and the amount of ILM present in ERM sp ecimens were quantified by manual counting.Outc ome measures in-clude change in best corrected visual acuity(BCVA),proportion of cases with 2or more lin es of visual im-provement,anatomic outcome,proportions of microscopic ERM within ILM,and microscopic ILM w ithin ERM.Results Eighteen eyes in 18patients were operated with a mean follow-up of 19.3months.There were 13primary ERMs and five secondary ERMs.The mea n logMAR BC-VA improved from 0.83preoperatively to 0.49postop-eratively(P<0.001).The mean lines of improvement in BCVA was 3.3lines with 14patients(77.8%)who had 2or more lines of BCVA improvemen t.Histologic e-valuation of the specimens showed no significant correla-tion with the final BCVA of 20/50or better.Eleven(61.1%)of the ILM specimens showed various a mount of microscopic ERM and 16(88.9%)of the ERM speci-mens showed various amount of ILM fra gments.The mean proportion of ERM within ILM specime ns was 4.69%and that of ILM within ERM specimens was 51.5%.No sig-nificant recurrence of ERM was found.Conclusion Re-currence of ERM may be minimized by re moving residual microscopic ERM present on the ILM.I ndocyaninegreen-assisted ILM peeling in ERM su rgery appears to have favorable visual and anatomic o utcomes.展开更多
文摘Background: Our aim was to assess the safety and efficacy of primary and secon dary implantation of a black diaphragm aniridia intraocular lens (IOL) in patien ts that lacked a complete iris diaphragm. Methods: This was a retrospective non -comparative study of six eyes in five patients with iris defects. The causes o f such defects included congenital aniridia, traumatic aniridia, and oculocutane ous albinism. Three eyes underwent primary implantations of a black diaphragm IO L, and three eyes were given secondary implantations. The visual acuity, subject ive severity of glare, postoperative anatomical outcome and any intraoperative o r postoperative complications were reviewed. Results: The mean follow-up period was 20.6 months (range 3-29 months. All patients showed stable or improvement in best-corrected visual acuity postoperatively. Glare and photophobia had impr oved subjectively in all patients after implantation of the black diaphragm IOL. Intraoperative complication included one case of hyphaema and iris damage durin g insertion of the IOL. Postoperative complications included intraocular inflamm ation with choroidal detachment, secondary glaucoma, and persistent epithelial d efect after surgery. None of the patients developed decentration of IOL after su rgery. Conclusion: The black diaphragm aniridia IOL is useful in the management of the condition in patients with iris deficiency including oculocutaneous albin ism. Intraoperative and postoperative complications are not uncommon, and patients should be monitored carefully in the perioperative period.
文摘Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.Design Interventional con secutive case series.Methods Patients scheduled for ERM s urgery were re-cruited prospectively.Pars plana v itrectomy,removal of ERM,and ILM peeling with indocyanin e green(ICG)staining were performed in all patie nts.Epiretinal mem-brane and ILM specimens were sent for histologic exam-ination.The amount of ERM present in ILM specimens and the amount of ILM present in ERM sp ecimens were quantified by manual counting.Outc ome measures in-clude change in best corrected visual acuity(BCVA),proportion of cases with 2or more lin es of visual im-provement,anatomic outcome,proportions of microscopic ERM within ILM,and microscopic ILM w ithin ERM.Results Eighteen eyes in 18patients were operated with a mean follow-up of 19.3months.There were 13primary ERMs and five secondary ERMs.The mea n logMAR BC-VA improved from 0.83preoperatively to 0.49postop-eratively(P<0.001).The mean lines of improvement in BCVA was 3.3lines with 14patients(77.8%)who had 2or more lines of BCVA improvemen t.Histologic e-valuation of the specimens showed no significant correla-tion with the final BCVA of 20/50or better.Eleven(61.1%)of the ILM specimens showed various a mount of microscopic ERM and 16(88.9%)of the ERM speci-mens showed various amount of ILM fra gments.The mean proportion of ERM within ILM specime ns was 4.69%and that of ILM within ERM specimens was 51.5%.No sig-nificant recurrence of ERM was found.Conclusion Re-currence of ERM may be minimized by re moving residual microscopic ERM present on the ILM.I ndocyaninegreen-assisted ILM peeling in ERM su rgery appears to have favorable visual and anatomic o utcomes.
