140例后节疾病序贯病例经结膜25G玻切手术预后

Purpose: To evaluate the safety and efficacy of 25-gauge instrumentation for a variety of vitreoretinal conditions on previously nonvitrectomized eyes. Design: Single-center, retrospective, interventional case series. Participants: One-hundred forty eyes of 140 patients were evaluated at the Doheny Retina Institute from July 2002 to July 2003. Intervention: All patients underwent surgical procedures using the Millennium 25-gauge Transconjunctival Standard Vitrectomy system. Twenty eyes (14.3%) underwent procedures without vitrectomy. Main Outcome Measures: Postoperative visual acuity (VA), intraocular pressure, surgical time, postoperative inflammation, complications, and number of sutured sites. Results: No intraoperative complications were noted. No cases required conversion to 20-gauge machines. Ten cases (7.1%) involved single-site sclerotomy suture placement due to bleb formation at the conclusion of the procedure, but 5 of these entry sites were enlarged to facilitate larger instrumentation for tissue manipulation. Median VA improved from 20/250 (logarithm of the minimum angle of resolution, 1.08±0.47) preoperatively to 20/60 (0.47±0.30)-(P< 0.0001) at final visit. Mean follow-upwas 33.8±9.7weeks, and all eyes were observed for a minimum of 12 weeks. Mean total surgical time was 17.4±6.9minutes. Intraocular pressures remained stable throughout the postoperative course. Five eyes (3.8%) presented on day 1 with shallow choroidal detachments, but all resolved by day 7, and none required volume infusion during the postoperative period. All but one of these cases was within the first 50 procedures performed. No detectable inflammation was noted in any eyes by 4 weeks postoperatively. No case of retinal detachment or endophthalmitis was recorded. Conclusions: Transconjunctival surgery using 25-gauge instrumentation may hasten postoperative recovery by decreasing overall surgical time and postoperative inflammation. Procedures requiring minimal intraocular manipulation did not require sutures and, thus, may be better suited for this surgical modality.

4期早产儿视网膜病变3通道保留晶状体式玻璃体切割术治疗后的视力预后

Objective:To assess the visual acuity of eyes successfully treated with 3-port lens-sparing vitrectomy for stage 4 retinopathy of prematurity.Methods:Of 102 consecutive eyes achieving at least posterior pole reattachment,30 eyes of 26 patients were tested by Teller or Allen acuity measurements and were subsequently converted to logarithm of the minimum angle of resolution(logMAR).Visual outcomes were also examined as either favorable or unfavorable(Snellen equivalent >20/200).Results:Seventy-two eyes were not tested because of either inability to performtesting(age or neurologic sequelae related to prematurity)or loss of follow-up.Of those tested,mean± SD logMAR visual acuity for the stage 4A and stage 4B groups was 0.51± 0.09(Snellen approximate 20/62)and 1.03± 0.19(Snellen approximate 20/200),respectively(odds ratio,0.39;95% confidence interval,0.24-0.64;P=.001).Of those eyes assessed by Teller measurements,10 of 10 stage 4A eyes and 3(37.5%)of 8 stage 4B eyes had favorable outcomes;among eyes assessed with Allen measurements,4 of 4 stage 4A eyes and 0 of 8 stage 4B eyes had favorable outcomes.Conclusions:The majority of eyes were not tested.Among eyes tested after successful 3-port lens-sparing vitrectomy,some eyes treated prior to macular detachment may be associated with a more favorable outcome and improved maintenance of functional visual acuity.